Dynamic modeling of the central carbon metabolism of Escherichia coli C Chassagnole, N Noisommit‐Rizzi, JW Schmid, K Mauch, M Reuss Biotechnology and bioengineering 79 (1), 53-73, 2002 | 714 | 2002 |
Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics D Visser, JW Schmid, K Mauch, M Reuss, JJ Heijnen Metabolic Engineering 6 (4), 378-390, 2004 | 142 | 2004 |
Metabolic flux analysis in Escherichia coli by integrating isotopic dynamic and isotopic stationary 13C labeling data J Schaub, K Mauch, M Reuss Biotechnology and bioengineering 99 (5), 1170-1185, 2008 | 123 | 2008 |
Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models E Gonçalves, J Bucher, A Ryll, J Niklas, K Mauch, S Klamt, M Rocha, ... Molecular BioSystems 9 (7), 1576-1583, 2013 | 111 | 2013 |
Identification of metabolic fluxes in hepatic cells from transient 13C‐labeling experiments: Part I. Experimental observations U Hofmann, K Maier, A Niebel, G Vacun, M Reuss, K Mauch Biotechnology and bioengineering 100 (2), 344-354, 2008 | 109 | 2008 |
Identification of metabolic fluxes in hepatic cells from transient 13C‐labeling experiments: Part II. Flux estimation K Maier, U Hofmann, M Reuss, K Mauch Biotechnology and bioengineering 100 (2), 355-370, 2008 | 105 | 2008 |
BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology AF Villaverde, D Henriques, K Smallbone, S Bongard, J Schmid, ... BMC systems biology 9, 1-15, 2015 | 89 | 2015 |
Metabolic design based on a coupled gene expression—metabolic network model of tryptophan production in Escherichia coli JW Schmid, K Mauch, M Reuss, ED Gilles, A Kremling Metabolic Engineering 6 (4), 364-377, 2004 | 88 | 2004 |
Integration of physiology and fluid dynamics S Schmalzriedt, M Jenne, K Mauch, M Reuss Process integration in biochemical engineering, 19-68, 2003 | 88 | 2003 |
A multi-scale modeling framework for individualized, spatiotemporal prediction of drug effects and toxicological risk JG Diaz Ochoa, J Bucher, ARR Péry, JM Zaldivar Comenges, J Niklas, ... Frontiers in pharmacology 3, 204, 2013 | 70 | 2013 |
Determination of in vivo kinetics of the starvation-induced Hxt5 glucose transporter of Saccharomyces cerevisiae S Buziol, J Becker, A Baumeister, S Jung, K Mauch, M Reuss, E Boles FEMS Yeast Research 2 (3), 283-291, 2002 | 68 | 2002 |
Tendency modeling: a new approach to obtain simplified kinetic models of metabolism applied to Saccharomyces cerevisiae D Visser, R van der Heijden, K Mauch, M Reuss, S Heijnen Metabolic Engineering 2 (3), 252-275, 2000 | 67 | 2000 |
Quantification of statin effects on hepatic cholesterol synthesis by transient 13C-flux analysis K Maier, U Hofmann, A Bauer, A Niebel, G Vacun, M Reuss, K Mauch Metabolic Engineering 11 (4-5), 292-309, 2009 | 65 | 2009 |
Dynamic sensitivity analysis for metabolic systems K Mauch, S Arnold, M Reuss Chemical Engineering Science 52 (15), 2589-2598, 1997 | 56 | 1997 |
Dynamics and control of the central carbon metabolism in hepatoma cells K Maier, U Hofmann, M Reuss, K Mauch BMC systems biology 4, 1-28, 2010 | 48 | 2010 |
A guide to gene regulatory network inference for obtaining predictive solutions: Underlying assumptions and fundamental biological and data constraints S Barbosa, B Niebel, S Wolf, K Mauch, R Takors Biosystems 174, 37-48, 2018 | 37 | 2018 |
Metabolic engineering with multi-objective optimization of kinetic models AF Villaverde, S Bongard, K Mauch, E Balsa-Canto, JR Banga Journal of biotechnology 222, 1-8, 2016 | 37 | 2016 |
Computer-aided design of metabolic networks K Mauch, S Buziol, J Schmid, M Reuss AIChE Symposium Series, 82-91, 2002 | 31 | 2002 |
A consensus approach for estimating the predictive accuracy of dynamic models in biology AF Villaverde, S Bongard, K Mauch, D Müller, E Balsa-Canto, J Schmid, ... Computer methods and programs in biomedicine 119 (1), 17-28, 2015 | 30 | 2015 |
The move toward biopharma 4.0: insilico biotechnology develops “smart” processes that benefit biomanufacturing through digital twins S Nargund, K Guenther, K Mauch Genetic Engineering & Biotechnology News 39 (6), 53-55, 2019 | 28 | 2019 |