Yosuke Demizu
Yosuke Demizu
National Institute of Health Sciences
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Regioselective protection of sugars catalyzed by dimethyltin dichloride.
Y Demizu, Y Kubo, H Miyoshi, T Maki, Y Matsumura, N Moriyama, ...
Organic Letters 10 (21), 5075-5077, 2008
Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells
K Okuhira, Y Demizu, T Hattori, N Ohoka, N Shibata, T Nishimaki‐Mogami, ...
Cancer science 104 (11), 1492-1498, 2013
Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
K Yamano, R Kikuchi, W Kojima, R Hayashida, F Koyano, J Kawawaki, ...
Journal of Cell Biology 219 (9), 2020
Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand
Y Demizu, N Shibata, T Hattori, N Ohoka, H Motoi, T Misawa, T Shoda, ...
Bioorganic & Medicinal Chemistry Letters 26 (20), 4865-4869, 2016
Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy
Y Demizu, K Okuhira, H Motoi, A Ohno, T Shoda, K Fukuhara, H Okuda, ...
Bioorganic & medicinal chemistry letters 22 (4), 1793-1796, 2012
Asymmetric oxidation of 1, 2-diols using N-bromosuccinimide in the presence of chiral copper catalyst
O Onomura, H Arimoto, Y Matsumura, Y Demizu
Tetrahedron Letters 48 (49), 8668-8672, 2007
Efficient oxidation of alcohols electrochemically mediated by azabicyclo-N-oxyls
Y Demizu, H Shiigi, T Oda, Y Matsumura, O Onomura
Tetrahedron Letters 49 (1), 48-52, 2008
Development of small molecule chimeras that recruit AhR E3 ligase to target proteins
N Ohoka, G Tsuji, T Shoda, T Fujisato, M Kurihara, Y Demizu, M Naito
ACS chemical biology 14 (12), 2822-2832, 2019
Development of a cell-penetrating peptide that exhibits responsive changes in its secondary structure in the cellular environment
H Yamashita, T Kato, M Oba, T Misawa, T Hattori, N Ohoka, M Tanaka, ...
Scientific Reports 6 (1), 33003, 2016
Amphipathic short helix-stabilized peptides with cell-membrane penetrating ability
H Yamashita, Y Demizu, T Shoda, Y Sato, M Oba, M Tanaka, M Kurihara
Bioorganic & medicinal chemistry 22 (8), 2403-2408, 2014
Conformational studies on peptides containing α, α-disubstituted α-amino acids: chiral cyclic α, α-disubstituted α-amino acid as an α-helical inducer
Y Demizu, M Doi, M Kurihara, H Okuda, M Nagano, H Suemune, ...
Organic & biomolecular chemistry 9 (9), 3303-3312, 2011
Chiral azabicyclo-N-oxyls mediated enantioselective electrooxidation of sec-alcohols
H Shiigi, H Mori, T Tanaka, Y Demizu, O Onomura
Tetrahedron Letters 49 (36), 5247-5251, 2008
Chiral centers in the side chains of α‐amino acids control the helical screw sense of peptides
M Tanaka, Y Demizu, M Doi, M Kurihara, H Suemune
Angewandte Chemie 116 (40), 5474-5477, 2004
Direct electrochemical α-cyanation of N-protected cyclic amines
SS Libendi, Y Demizu, O Onomura
Organic & Biomolecular Chemistry 7 (2), 351-356, 2009
One‐Handed Helical Screw Direction of Homopeptide Foldamer Exclusively Induced by Cyclic α‐Amino Acid Side‐Chain Chiral Centers
Y Demizu, M Doi, M Kurihara, T Maruyama, H Suemune, M Tanaka
Chemistry–A European Journal 18 (8), 2430-2439, 2012
A synthetic cannabinoid FDU-NNEI, two 2 H-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N–OH-EDMA, and a …
N Uchiyama, Y Shimokawa, R Kikura-Hanajiri, Y Demizu, Y Goda, ...
Forensic toxicology 33, 244-259, 2015
Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids
T Kato, H Yamashita, T Misawa, K Nishida, M Kurihara, M Tanaka, ...
Bioorganic & Medicinal Chemistry 24 (12), 2681-2687, 2016
A helix‐stabilized cell‐penetrating peptide as an intracellular delivery tool
H Yamashita, M Oba, T Misawa, M Tanaka, T Hattori, M Naito, M Kurihara, ...
ChemBioChem 17 (2), 137-140, 2016
Copper complex catalyzed asymmetric monosulfonylation of meso-vic-diols
Y Demizu, K Matsumoto, O Onomura, Y Matsumura
Tetrahedron Letters 48 (43), 7605-7609, 2007
Enantioselective epoxidation of α, β-unsaturated ketones catalyzed by stapled helical L-Leu-based peptides
Y Demizu, N Yamagata, S Nagoya, Y Sato, M Doi, M Tanaka, ...
Tetrahedron 67 (34), 6155-6165, 2011
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