Regioselective protection of sugars catalyzed by dimethyltin dichloride. Y Demizu, Y Kubo, H Miyoshi, T Maki, Y Matsumura, N Moriyama, ... Organic Letters 10 (21), 5075-5077, 2008 | 156 | 2008 |
Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells K Okuhira, Y Demizu, T Hattori, N Ohoka, N Shibata, T Nishimaki‐Mogami, ... Cancer science 104 (11), 1492-1498, 2013 | 145 | 2013 |
Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy K Yamano, R Kikuchi, W Kojima, R Hayashida, F Koyano, J Kawawaki, ... Journal of Cell Biology 219 (9), 2020 | 142 | 2020 |
Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand Y Demizu, N Shibata, T Hattori, N Ohoka, H Motoi, T Misawa, T Shoda, ... Bioorganic & Medicinal Chemistry Letters 26 (20), 4865-4869, 2016 | 130 | 2016 |
Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy Y Demizu, K Okuhira, H Motoi, A Ohno, T Shoda, K Fukuhara, H Okuda, ... Bioorganic & medicinal chemistry letters 22 (4), 1793-1796, 2012 | 102 | 2012 |
Asymmetric oxidation of 1, 2-diols using N-bromosuccinimide in the presence of chiral copper catalyst O Onomura, H Arimoto, Y Matsumura, Y Demizu Tetrahedron Letters 48 (49), 8668-8672, 2007 | 100 | 2007 |
Efficient oxidation of alcohols electrochemically mediated by azabicyclo-N-oxyls Y Demizu, H Shiigi, T Oda, Y Matsumura, O Onomura Tetrahedron Letters 49 (1), 48-52, 2008 | 88 | 2008 |
Development of small molecule chimeras that recruit AhR E3 ligase to target proteins N Ohoka, G Tsuji, T Shoda, T Fujisato, M Kurihara, Y Demizu, M Naito ACS chemical biology 14 (12), 2822-2832, 2019 | 85 | 2019 |
Development of a cell-penetrating peptide that exhibits responsive changes in its secondary structure in the cellular environment H Yamashita, T Kato, M Oba, T Misawa, T Hattori, N Ohoka, M Tanaka, ... Scientific Reports 6 (1), 33003, 2016 | 80 | 2016 |
Conformational studies on peptides containing α, α-disubstituted α-amino acids: chiral cyclic α, α-disubstituted α-amino acid as an α-helical inducer Y Demizu, M Doi, M Kurihara, H Okuda, M Nagano, H Suemune, ... Organic & biomolecular chemistry 9 (9), 3303-3312, 2011 | 76 | 2011 |
Amphipathic short helix-stabilized peptides with cell-membrane penetrating ability H Yamashita, Y Demizu, T Shoda, Y Sato, M Oba, M Tanaka, M Kurihara Bioorganic & medicinal chemistry 22 (8), 2403-2408, 2014 | 72 | 2014 |
Chiral azabicyclo-N-oxyls mediated enantioselective electrooxidation of sec-alcohols H Shiigi, H Mori, T Tanaka, Y Demizu, O Onomura Tetrahedron Letters 49 (36), 5247-5251, 2008 | 71 | 2008 |
TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains AI Kaiho-Soma, Y Akizuki, K Igarashi, A Endo, T Shoda, Y Kawase, ... Molecular cell 81 (7), 1411-1424. e7, 2021 | 68 | 2021 |
Direct electrochemical α-cyanation of N-protected cyclic amines SS Libendi, Y Demizu, O Onomura Organic & Biomolecular Chemistry 7 (2), 351-356, 2009 | 67 | 2009 |
Chiral centers in the side chains of α‐amino acids control the helical screw sense of peptides M Tanaka, Y Demizu, M Doi, M Kurihara, H Suemune Angewandte Chemie International Edition 43 (40), 5360-5363, 2004 | 64 | 2004 |
A helix‐stabilized cell‐penetrating peptide as an intracellular delivery tool H Yamashita, M Oba, T Misawa, M Tanaka, T Hattori, M Naito, M Kurihara, ... ChemBioChem 17 (2), 137-140, 2016 | 60 | 2016 |
Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator N Akiyama, N Takizawa, M Miyauchi, H Yanai, R Tateishi, M Shinzawa, ... Journal of Experimental Medicine 213 (8), 1441-1458, 2016 | 59 | 2016 |
A synthetic cannabinoid FDU-NNEI, two 2 H-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N–OH-EDMA, and a … N Uchiyama, Y Shimokawa, R Kikura-Hanajiri, Y Demizu, Y Goda, ... Forensic toxicology 33, 244-259, 2015 | 57 | 2015 |
Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids T Kato, H Yamashita, T Misawa, K Nishida, M Kurihara, M Tanaka, ... Bioorganic & Medicinal Chemistry 24 (12), 2681-2687, 2016 | 56 | 2016 |
One‐Handed Helical Screw Direction of Homopeptide Foldamer Exclusively Induced by Cyclic α‐Amino Acid Side‐Chain Chiral Centers Y Demizu, M Doi, M Kurihara, T Maruyama, H Suemune, M Tanaka Chemistry–A European Journal 18 (8), 2430-2439, 2012 | 56 | 2012 |