フォロー
Chad A. Dumstorf
Chad A. Dumstorf
Wood Hudson Cancer Research Laboratory
確認したメール アドレス: woodhudson.org
タイトル
引用先
引用先
eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival
JR Graff, BW Konicek, RL Lynch, CA Dumstorf, MS Dowless, AM McNulty, ...
Cancer research 69 (9), 3866-3873, 2009
2532009
Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases
BW Konicek, JR Stephens, AM McNulty, N Robichaud, RB Peery, ...
Cancer research 71 (5), 1849-1857, 2011
2472011
Participation of mouse DNA polymerase ι in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer
CA Dumstorf, AB Clark, Q Lin, GE Kissling, T Yuan, R Kucherlapati, ...
Proceedings of the National Academy of Sciences 103 (48), 18083-18088, 2006
1282006
Participation of mouse DNA polymerase ι in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer
CA Dumstorf, AB Clark, Q Lin, GE Kissling, T Yuan, R Kucherlapati, ...
Proceedings of the National Academy of Sciences 103 (48), 18083-18088, 2006
1282006
Targeting the eIF4F translation initiation complex for cancer therapy
BW Konicek, CA Dumstorf, JR Graff
Cell Cycle 7 (16), 2466-2471, 2008
832008
REV1 is implicated in the development of carcinogen-induced lung cancer
CA Dumstorf, S Mukhopadhyay, E Krishnan, B Haribabu, WG McGregor
Molecular Cancer Research 7 (2), 247-254, 2009
642009
Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis
CA Dumstorf, BW Konicek, AM McNulty, SH Parsons, L Furic, ...
Molecular cancer therapeutics 9 (12), 3158-3163, 2010
472010
Abstract LB-302: eIF4E phosphorylation is Mnk-dependent but does not require assembly of the eIF4F translation initiation complex
C Hall, C Dumstorf, B Konicek, N Robichaud, A McNulty, S Parsons, ...
Cancer Research 74 (19_Supplement), LB-302-LB-302, 2014
32014
Abstract LB-302: eIF4E phosphorylation is Mnk-dependent but does not require assembly of the eIF4F translation initiation complex
C Hall, C Dumstorf, B Konicek, N Robichaud, A McNulty, S Parsons, ...
Cancer Research 74 (19_Supplement), LB-302-LB-302, 2014
32014
Disruption of the eIF4F translation initiation complex as a determinant of diffuse large B-cell lymphoma responsiveness to enzastaurin (LY317615. HCl) and its primary …
JR Graff, AM McNulty, CA Dumstorf, SH Parsons, BW Konicek, CA Hall
Journal of Clinical Oncology 30 (15_suppl), 8082-8082, 2012
12012
Phosphorylation of eIF4E is a critical factor in development and progression of breast cancer in women
CA Dumstorf, LE Douglass, JA Deddens, TG Lewis, K Darpel, C Gausvik, ...
Cancer Research 76 (14_Supplement), 3919-3919, 2016
2016
The Direct Anti-Tumor Activity of Enzastaurin (LY317615. HCl) and Its Primary Metabolite (LY326020. HCl) Is Evident in Preclinical DLBCL Models Regardless of Molecular Subtype
JR Graff, AM McNulty, C Dumstorf, B Konicek, C Hall, S Parsons
Blood 120 (21), 1336, 2012
2012
Sensitivity of diffuse large B cell lymphoma cells to Enzastaurin (LY317615. HCl) and its primary metabolite (LY326020) is critically dependent upon disruption of the eIF4F …
AM McNulty, CA Dumstorf, CA Dumstorf, SH Parsons, BW Konicek, ...
CANCER RESEARCH 72, 2012
2012
Abstract LB-235: Sensitivity of diffuse large B cell lymphoma cells to Enzastaurin (LY317615. HCl) and its primary metabolite (LY326020) is critically dependent upon disruption …
AM McNulty, CA Dumstorf, CA Dumstorf, SH Parsons, BW Konicek, ...
Cancer Research 72 (8_Supplement), LB-235-LB-235, 2012
2012
489 Enzastaurin (LY317615. HCl) and Its Primary Metabolite (LY326020. HCl) Exert Antitumor Effects in Diffuse Large B Cell Lymphoma Through Multiple Mechanisms, Most Notably …
J Graff, AM McNulty, C Dumstorf, S Parsons, BW Konicek, C Hall
European Journal of Cancer, 151-152, 2012
2012
Abstract A237: Elevated Mnk kinase activity is associated with malignant progression and reduced patient survival in human prostate cancer and can be therapeutically inhibited …
B Konicek, C Hall, C Dumstorf, B Colligan, S Dong, S Na, J Deddens, ...
Molecular Cancer Therapeutics 10 (11_Supplement), A237-A237, 2011
2011
Elevated eIF4E phosphorylation is associated with advanced malignancy and decreased patient survival and can be therapeutically inhibited by a novel, orally bio-available Mnk …
JR Graff, B Konicek, C Dumstorf, S Siwko, B Colligan, JA Deddens, ...
CANCER RESEARCH 71, 2011
2011
Abstract LB-384: Elevated eIF4E phosphorylation is associated with advanced malignancy and decreased patient survival and can be therapeutically inhibited by a novel, orally …
JR Graff, B Konicek, C Dumstorf, S Siwko, B Colligan, JA Deddens, ...
Cancer Research 71 (8_Supplement), LB-384-LB-384, 2011
2011
Human prostate cancer progression universally involves elevated eIF4E activation coincident with reduced survival: eIF4E ASO treatment suppresses prostate cancer xenograft …
J Graff, B Konicek, C Dumstorf, R Lynch, S Weir, D Capen, P Schwier, ...
Cancer Research 68 (9_Supplement), LB-118-LB-118, 2008
2008
REV1 inhibition reduces the incidence of carcinogen-induced murine lung tumors.
CD Dumstorf, SM Mukhopadhyay, WZ Zacharias, WM McGregor
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 48 (7), 623-623, 2007
2007
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