Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ... Nature metabolism 2 (11), 1265-1283, 2020 | 253 | 2020 |
Nuclear morphology is a deep learning biomarker of cellular senescence I Heckenbach, GV Mkrtchyan, MB Ezra, D Bakula, JS Madsen, ... Nature Aging 2 (8), 742-755, 2022 | 62 | 2022 |
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health Brown University TDA Wang Siyuan (Steven) 34, ... Nature aging 2 (12), 1090-1100, 2022 | 36 | 2022 |
Spatial mapping of cellular senescence: emerging challenges and opportunities AU Gurkar, AA Gerencser, AL Mora, AC Nelson, AR Zhang, AB Lagnado, ... Nature aging 3 (7), 776-790, 2023 | 22 | 2023 |
A compound duration model for high-frequency asset returns EM Aldrich, I Heckenbach, G Laughlin Journal of Empirical Finance 39, 105-128, 2016 | 15* | 2016 |
Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis AB Herman, C Anerillas, SC Harris, R Munk, JL Martindale, X Yang, ... Nucleic Acids Research 49 (13), 7389-7405, 2021 | 14 | 2021 |
Histone malonylation is regulated by SIRT5 and KAT2A R Zhang, J Bons, G Scheidemantle, X Liu, O Bielska, C Carrico, J Rose, ... Iscience 26 (3), 2023 | 7 | 2023 |
CD38 regulates ovarian function and fecundity via NAD+ metabolism R Perrone, PVA Kumaar, L Haky, C Hahn, R Riley, J Balough, G Zaza, ... Iscience 26 (10), 2023 | 3 | 2023 |
The human pathome shows sex specific aging patterns post-development MB Ezra, JB Garbrecht, N Rasmussen, I Heckenbach, MA Petr, D Bakula, ... bioRxiv, 2023.02. 27.530179, 2023 | 2 | 2023 |
A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function R Boutoual, H Jo, I Heckenbach, R Tiwari, H Kasler, CA Lerner, S Shah, ... Scientific Reports 12 (1), 14804, 2022 | 2 | 2022 |
Tracking the dynamics of cellular senescence I Heckenbach, M Scheibye-Knudsen Aging (Albany NY) 15 (9), 3219, 2023 | 1 | 2023 |
Breast cancer risk based on a deep learning predictor of senescent cells in normal tissue I Heckenbach, M Powell, S Fuller, J Henry, S Rysdyk, J Cui, AA Teklu, ... medRxiv, 2023.05. 22.23290327, 2023 | 1 | 2023 |
Nicotinamide Riboside Alleviates Airway Inflammation in Chronic Obstructive Pulmonary Disease KL Norheim, M Ben Ezra, I Heckenbach, LM Andreasson, MV Damgaard, ... Available at SSRN 4425875, 2023 | 1 | 2023 |
Ketones facilitate transcriptional resolution of secondary DNA structures in premature aging MA Petr, LM Carmona-Marin, T Tulika, S Kristensen, S Reves, D Bakula, ... bioRxiv, 2022.03. 08.483430, 2022 | 1 | 2022 |
Chronically disrupted sleep induces senescence in the visceral adipose tissue of C57BL/6J mice D Timonina, GV Hormazabal, I Heckenbach, E Anderton, L Haky, A Floro, ... bioRxiv, 2023.10. 17.562803, 2023 | | 2023 |
Research briefing I Heckenbach, M Scheibye-Knudsen | | 2022 |
Understanding Stem Cell Pluripotency and Differentiation as a Complex Dynamic System I Heckenbach Niels Bohr Institute, Copenhagen University, 2018 | | 2018 |
Center for Analytical Finance University of California, Santa Cruz EM Aldrich, I Heckenbach, G Laughlin | | 2014 |