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Kazuhiro Iwai
Kazuhiro Iwai
Verified email at mcp.med.kyoto-u.ac.jp - Homepage
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Cited by
Year
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
H Shimura, N Hattori, S Kubo, Y Mizuno, S Asakawa, S Minoshima, ...
Nature genetics 25 (3), 302-305, 2000
25502000
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
G Levkowitz, H Waterman, SA Ettenberg, M Katz, AY Tsygankov, I Alroy, ...
Molecular cell 4 (6), 1029-1040, 1999
12511999
Involvement of linear polyubiquitylation of NEMO in NF-κB activation
F Tokunaga, S Sakata, Y Saeki, Y Satomi, T Kirisako, K Kamei, ...
Nature cell biology 11 (2), 123-132, 2009
11052009
A ubiquitin ligase complex assembles linear polyubiquitin chains
T Kirisako, K Kamei, S Murata, M Kato, H Fukumoto, M Kanie, S Sano, ...
The EMBO journal 25 (20), 4877-4887, 2006
9062006
Activation of HIF1α ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
T Kamura, S Sato, K Iwai, M Czyzyk-Krzeska, RC Conaway, JW Conaway
Proceedings of the National Academy of Sciences 97 (19), 10430-10435, 2000
8462000
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
F Ikeda, YL Deribe, SS Skånland, B Stieglitz, C Grabbe, M Franz-Wachtel, ...
Nature 471 (7340), 637-641, 2011
7842011
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
F Tokunaga, T Nakagawa, M Nakahara, Y Saeki, M Taniguchi, S Sakata, ...
Nature 471 (7340), 633-636, 2011
6552011
Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
K Iwai, K Yamanaka, T Kamura, N Minato, RC Conaway, JW Conaway, ...
Proceedings of the National Academy of Sciences 96 (22), 12436-12441, 1999
6231999
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
T LaVaute, S Smith, S Cooperman, K Iwai, W Land, E Meyron-Holtz, ...
Nature genetics 27 (2), 209-214, 2001
5622001
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
EG Meyron‐Holtz, MC Ghosh, K Iwai, T LaVaute, X Brazzolotto, ...
The EMBO journal 23 (2), 386-395, 2004
4692004
E3 ubiquitin ligase that recognizes sugar chains
Y Yoshida, T Chiba, F Tokunaga, H Kawasaki, K Iwai, T Suzuki, Y Ito, ...
Nature 418 (6896), 438-442, 2002
4302002
NEDD8 recruits E2‐ubiquitin to SCF E3 ligase
T Kawakami, T Chiba, T Suzuki, K Iwai, K Yamanaka, N Minato, H Suzuki, ...
The EMBO journal, 2001
4022001
Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation
K Ishii, T Fumoto, K Iwai, S Takeshita, M Ito, N Shimohata, H Aburatani, ...
Nature medicine 15 (3), 259-266, 2009
3952009
Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins
K Iwai, SK Drake, NB Wehr, AM Weissman, T LaVaute, N Minato, ...
Proceedings of the National Academy of Sciences 95 (9), 4924-4928, 1998
3871998
Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
Y Sato, A Yoshikawa, A Yamagata, H Mimura, M Yamashita, K Ookata, ...
Nature 455 (7211), 358-362, 2008
3852008
4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer
E Nakamura, M Sato, H Yang, F Miyagawa, M Harasaki, K Tomita, ...
Journal of Biological Chemistry 274 (5), 3009-3016, 1999
3661999
Heme induces ubiquitination and degradation of the transcription factor Bach1
Y Zenke-Kawasaki, Y Dohi, Y Katoh, T Ikura, M Ikura, T Asahara, ...
Molecular and cellular biology 27 (19), 6962-6971, 2007
3272007
Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin
N Fujita, E Morita, T Itoh, A Tanaka, M Nakaoka, Y Osada, T Umemoto, ...
Journal of Cell Biology 203 (1), 115-128, 2013
2872013
Linear polyubiquitination: a new regulator of NF‐κB activation
K Iwai, F Tokunaga
EMBO reports 10 (7), 706-713, 2009
2832009
Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation.
F Samaniego, J Chin, K Iwai, TA Rouault, RD Klausner
Journal of Biological Chemistry 269 (49), 30904-30910, 1994
2711994
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