Mutations in EFHC1 cause juvenile myoclonic epilepsy T Suzuki, AV Delgado-Escueta, K Aguan, ME Alonso, J Shi, Y Hara, ... Nature genetics 36 (8), 842-849, 2004 | 422 | 2004 |
Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound S Kiyonaka, K Kato, M Nishida, K Mio, T Numaga, Y Sawaguchi, ... Proceedings of the National Academy of Sciences 106 (13), 5400-5405, 2009 | 409 | 2009 |
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade C Koike, T Obara, Y Uriu, T Numata, R Sanuki, K Miyata, T Koyasu, ... Proceedings of the National Academy of Sciences 107 (1), 332-337, 2010 | 330 | 2010 |
TRPA1 underlies a sensing mechanism for O2 N Takahashi, T Kuwaki, S Kiyonaka, T Numata, D Kozai, Y Mizuno, ... Nature chemical biology 7 (10), 701-711, 2011 | 305 | 2011 |
A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl- channel T Shimizu, T Numata, Y Okada Proceedings of the National Academy of Sciences 101 (17), 6770-6773, 2004 | 280 | 2004 |
TRPM7 is a stretch-and swelling-activated cation channel involved in volume regulation in human epithelial cells T Numata, T Shimizu, Y Okada American Journal of Physiology-Cell Physiology 292 (1), C460-C467, 2007 | 245 | 2007 |
Pathophysiology and puzzles of the volume‐sensitive outwardly rectifying anion channel Y Okada, K Sato, T Numata The Journal of physiology 587 (10), 2141-2149, 2009 | 177 | 2009 |
Direct mechano-stress sensitivity of TRPM7 channel T Numata, T Shimizu, Y Okada Cellular Physiology and Biochemistry 19 (1-4), 1-8, 2007 | 149 | 2007 |
Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface‐Engineered Plasmonic Nanoparticles H Nakatsuji, T Numata, N Morone, S Kaneko, Y Mori, H Imahori, ... Angewandte Chemie International Edition 54 (40), 11725-11729, 2015 | 121 | 2015 |
Rim2α determines docking and priming states in insulin granule exocytosis T Yasuda, T Shibasaki, K Minami, H Takahashi, A Mizoguchi, Y Uriu, ... Cell metabolism 12 (2), 117-129, 2010 | 119 | 2010 |
TRPM1: a vertebrate TRP channel responsible for retinal ON bipolar function C Koike, T Numata, H Ueda, Y Mori, T Furukawa Cell calcium 48 (2-3), 95-101, 2010 | 109 | 2010 |
Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS T Miyake, S Nakamura, M Zhao, K So, K Inoue, T Numata, N Takahashi, ... Nature communications 7 (1), 12840, 2016 | 108 | 2016 |
Impaired activity of volume‐sensitive Cl− channel is involved in cisplatin resistance of cancer cells EL Lee, T Shimizu, T Ise, T Numata, K Kohno, Y Okada Journal of cellular physiology 211 (2), 513-521, 2007 | 97 | 2007 |
Cell volume-activated and volume-correlated anion channels in mammalian cells: their biophysical, molecular, and pharmacological properties Y Okada, T Okada, K Sato-Numata, MR Islam, Y Ando-Akatsuka, ... Pharmacological reviews 71 (1), 49-88, 2019 | 78 | 2019 |
Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner Y Nakamura, X Shi, T Numata, Y Mori, R Inoue, C Lossin, TZ Baram, ... PloS one 8 (12), e80376, 2013 | 70 | 2013 |
Active zone protein Bassoon co-localizes with presynaptic calcium channel, modifies channel function, and recovers from aging related loss by exercise H Nishimune, T Numata, J Chen, Y Aoki, Y Wang, MP Starr, Y Mori, ... PLoS One 7 (6), e38029, 2012 | 61 | 2012 |
The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death M Katano, T Numata, K Aguan, Y Hara, S Kiyonaka, S Yamamoto, T Miki, ... Cell calcium 51 (2), 179-185, 2012 | 57 | 2012 |
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry K Yamaura, S Kiyonaka, T Numata, R Inoue, I Hamachi Nature Chemical Biology 12 (10), 822-830, 2016 | 56 | 2016 |
Role of acid-sensitive outwardly rectifying anion channels in acidosis-induced cell death in human epithelial cells HY Wang, T Shimizu, T Numata, Y Okada Pflügers Archiv-European Journal of Physiology 454, 223-233, 2007 | 55 | 2007 |
Utilization of photoinduced charge-separated state of donor–acceptor-linked molecules for regulation of cell membrane potential and ion transport T Numata, T Murakami, F Kawashima, N Morone, JE Heuser, Y Takano, ... Journal of the American Chemical Society 134 (14), 6092-6095, 2012 | 52 | 2012 |