Developmental plasticity allows outside-in immune responses by resident memory T cells R Fonseca, LK Beura, CF Quarnstrom, HE Ghoneim, Y Fan, CC Zebley, ... Nature immunology 21 (4), 412-421, 2020 | 238 | 2020 |
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity B Prinzing, CC Zebley, CT Petersen, Y Fan, AA Anido, Z Yi, P Nguyen, ... Science translational medicine 13 (620), eabh0272, 2021 | 147 | 2021 |
Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis HA Abdelsamed, A Moustaki, Y Fan, P Dogra, HE Ghoneim, CC Zebley, ... Journal of Experimental Medicine 214 (6), 1593-1606, 2017 | 140 | 2017 |
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes HA Abdelsamed, CC Zebley, H Nguyen, RL Rutishauser, Y Fan, ... Nature immunology 21 (5), 578-587, 2020 | 75 | 2020 |
CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia CC Zebley, C Brown, T Mi, Y Fan, S Alli, S Boi, G Galletti, E Lugli, ... Cell reports 37 (9), 2021 | 53 | 2021 |
Rewriting history: epigenetic reprogramming of CD8+ T cell differentiation to enhance immunotherapy CC Zebley, S Gottschalk, B Youngblood Trends in immunology 41 (8), 665-675, 2020 | 47 | 2020 |
Regnase-1 suppresses TCF-1+ precursor exhausted T-cell formation to limit CAR–T-cell responses against ALL W Zheng, J Wei, CC Zebley, LL Jones, Y Dhungana, YD Wang, J Mavuluri, ... Blood, The Journal of the American Society of Hematology 138 (2), 122-135, 2021 | 37 | 2021 |
Epigenetic maintenance of acquired gene expression programs during memory CD8 T cell homeostasis HA Abdelsamed, CC Zebley, B Youngblood Frontiers in immunology 9, 329016, 2018 | 31 | 2018 |
Mechanisms of T cell exhaustion guiding next-generation immunotherapy CC Zebley, B Youngblood Trends in cancer 8 (9), 726-734, 2022 | 25 | 2022 |
Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL AC Talleur, A Qudeimat, JY Métais, D Langfitt, E Mamcarz, JC Crawford, ... Blood Advances 6 (21), 5737-5749, 2022 | 22 | 2022 |
Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation CC Zebley, HA Abdelsamed, HE Ghoneim, S Alli, C Brown, D Haydar, ... Cell reports 37 (2), 2021 | 17 | 2021 |
Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion C Lamarche, K Ward-Hartstonge, T Mi, DTS Lin, Q Huang, A Brown, ... Proceedings of the National Academy of Sciences 120 (14), e2219086120, 2023 | 15 | 2023 |
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci. Transl. Med. 13, eabh0272 B Prinzing, CC Zebley, CT Petersen, Y Fan, AA Anido, Z Yi, P Nguyen, ... | 11 | 2021 |
CAR T cells need a pitstop to win the race CC Zebley, B Youngblood Cancer Cell 39 (6), 756-758, 2021 | 8 | 2021 |
Cellular and molecular waypoints along the path of T cell exhaustion X Lan, CC Zebley, B Youngblood Science immunology 8 (87), eadg3868, 2023 | 6 | 2023 |
De novo DNA methylation programs regulate CAR T-cell exhaustion CC Zebley, CT Petersen, B Prinzing, M Bell, Y Fan, JC Crawford, H Houke, ... The Journal of Immunology 204 (1_Supplement), 246.5-246.5, 2020 | 5 | 2020 |
Human Memory CD8 T Cell Effector Potential Is Epigenetically Preserved During HA Abdelsamed, A Moustaki, Y Fan, P Dogra, HE Ghoneim, CC Zebley Vivo, 0 | 5 | |
Defining the molecular hallmarks of T-cell memory CC Zebley, RS Akondy, BA Youngblood, HT Kissick Cold Spring Harbor Perspectives in Biology 14 (3), a037804, 2022 | 4 | 2022 |
In vitro homeostatic proliferation of human CD8 T cells HA Abdelsamed, CC Zebley, B Youngblood Bio-protocol 7 (22), e2619-e2619, 2017 | 4 | 2017 |
HIV-Specific CD8 T cells from elite controllers have an epigenetic imprint that preserves effector functions AB Frias, RL Rutishauser, AA Sharma, T Mi, H Abdelsamed, C Zebley, ... bioRxiv, 2021.09. 28.459512, 2021 | 2 | 2021 |