Autologous induced stem-cell–derived retinal cells for macular degeneration M Mandai, A Watanabe, Y Kurimoto, Y Hirami, C Morinaga, T Daimon, ... New England Journal of Medicine 376 (11), 1038-1046, 2017 | 884 | 2017 |
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B T Yamauchi, K Hara, S Maeda, K Yasuda, A Takahashi, M Horikoshi, ... Nature genetics 42 (10), 864-868, 2010 | 290 | 2010 |
Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential. TK Ohnuki M, Tanabe K, Sutou K, Teramoto I, Sawamura Y, Narita M, Nakamura M ... Proc Natl Acad Sci U S A. 111 (34), 12426-31, 2014 | 164* | 2014 |
Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity M Nishizawa, K Chonabayashi, M Nomura, A Tanaka, M Nakamura, ... Cell stem cell 19 (3), 341-354, 2016 | 137 | 2016 |
Global mapping of cell type–specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation H Waki, M Nakamura, T Yamauchi, K Wakabayashi, J Yu, ... PLoS Genet 7 (10), e1002311, 2011 | 118 | 2011 |
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations M Imamura, S Maeda, T Yamauchi, K Hara, K Yasuda, T Morizono, ... Human molecular genetics 21 (13), 3042-3049, 2012 | 101 | 2012 |
Targeted conversion of the transthyretin gene in vitro and in vivo M Nakamura, Y Ando, S Nagahara, A Sano, T Ochiya, S Maeda, T Kawaji, ... Gene Therapy 11 (10), 838-846, 2004 | 68 | 2004 |
Valproic acid induces apoptosis dependent of Yca1p at concentrations that mildly affect the proliferation of yeast K Mitsui, D Nakagawa, M Nakamura, T Okamoto, K Tsurugi FEBS letters 579 (3), 723-727, 2005 | 62 | 2005 |
Common origin of the Val30Met mutation responsible for the amyloidogenic transthyretin type of familial amyloidotic polyneuropathy H Ohmori, Y Ando, Y Makita, Y Onouchi, T Nakajima, MJM Saraiva, ... Journal of medical genetics 41 (4), e51-e51, 2004 | 58 | 2004 |
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3 Y Yahara, H Takemori, M Okada, A Kosai, A Yamashita, T Kobayashi, ... Nature communications 7 (1), 1-14, 2016 | 51 | 2016 |
A novel compound heterozygote (FAP ATTR Arg104His/ATTR Val30Met) with high serum transthyretin (TTR) and retinol binding protein (RBP) levels H Terazaki, Y Ando, S Misumi, M Nakamura, E Ando, N Matsunaga, ... Biochemical and biophysical research communications 264 (2), 365-370, 1999 | 51 | 1999 |
Nat1 promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells H Sugiyama, K Takahashi, T Yamamoto, M Iwasaki, M Narita, ... Proceedings of the National Academy of Sciences 114 (2), 340-345, 2017 | 42 | 2017 |
OVOL2 maintains the transcriptional program of human corneal epithelium by suppressing epithelial-to-mesenchymal transition K Kitazawa, T Hikichi, T Nakamura, K Mitsunaga, A Tanaka, M Nakamura, ... Cell reports 15 (6), 1359-1368, 2016 | 40 | 2016 |
Adiponectin, adiponectin receptors, and epigenetic regulation of adipogenesis T Kadowaki, T Yamauchi, H Waki, M Iwabu, M Okada-Iwabu, M Nakamura Cold Spring Harbor symposia on quantitative biology 76, 257-265, 2011 | 35 | 2011 |
NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program Y Hiraike, H Waki, J Yu, M Nakamura, K Miyake, G Nagano, R Nakaki, ... Nature cell biology 19 (9), 1081-1092, 2017 | 33 | 2017 |
Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models T Ameku, D Taura, M Sone, T Numata, M Nakamura, F Shiota, T Toyoda, ... Scientific reports 6 (1), 1-14, 2016 | 23 | 2016 |
Rho-associated kinases and non-muscle myosin IIs inhibit the differentiation of human iPSCs to pancreatic endoderm T Toyoda, A Kimura, H Tanaka, T Ameku, A Mima, Y Hirose, M Nakamura, ... Stem cell reports 9 (2), 419-428, 2017 | 20 | 2017 |
Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells Y Kondo, T Toyoda, R Ito, M Funato, Y Hosokawa, S Matsui, T Sudo, ... Diabetologia 60 (8), 1454-1466, 2017 | 20 | 2017 |
Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability. SH Ueki J, Nakamori M, Nakamura M, Nishikawa M, Yoshida Y, Tanaka A ... Scientific reports 7, 42522, 2017 | 19* | 2017 |
Redefining definitive endoderm subtypes by robust induction of human induced pluripotent stem cells K Matsuno, SI Mae, C Okada, M Nakamura, A Watanabe, T Toyoda, ... Differentiation 92 (5), 281-290, 2016 | 19 | 2016 |