Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS AC Elden, HJ Kim, MP Hart, AS Chen-Plotkin, BS Johnson, X Fang, ... Nature 466 (7310), 1069-1075, 2010 | 1386 | 2010 |
A yeast functional screen predicts new candidate ALS disease genes J Couthouis, MP Hart, J Shorter, M DeJesus-Hernandez, R Erion, ... Proceedings of the National Academy of Sciences 108 (52), 20881-20890, 2011 | 441 | 2011 |
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models HJ Kim, AR Raphael, ES LaDow, L McGurk, RA Weber, JQ Trojanowski, ... Nature genetics 46 (2), 152-160, 2014 | 404 | 2014 |
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis J Couthouis, MP Hart, R Erion, OD King, Z Diaz, T Nakaya, F Ibrahim, ... Human molecular genetics 21 (13), 2899-2911, 2012 | 298 | 2012 |
The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies M Jo, S Lee, YM Jeon, S Kim, Y Kwon, HJ Kim Experimental & molecular medicine 52 (10), 1652-1662, 2020 | 199 | 2020 |
Prion-like mechanism in amyotrophic lateral sclerosis: are protein aggregates the key? S Lee, HJ Kim Experimental neurobiology 24 (1), 1, 2015 | 137 | 2015 |
DEN1 deneddylates non-cullin proteins in vivo Y Chan, J Yoon, JT Wu, HJ Kim, KT Pan, J Yim, CT Chien Journal of cell science 121 (19), 3218-3223, 2008 | 84 | 2008 |
The F-actin-microtubule crosslinker Shot is a platform for Krasavietz-mediated translational regulation of midline axon repulsion S Lee, M Nahm, M Lee, M Kwon, E Kim, AD Zadeh, H Cao, HJ Kim, ... Oxford University Press for The Company of Biologists Limited 134 (9), 1767-1777, 2007 | 72 | 2007 |
Mitochondrial chaperone HSP‐60 regulates anti‐bacterial immunity via p38 MAP kinase signaling DE Jeong, D Lee, SY Hwang, Y Lee, JE Lee, M Seo, W Hwang, K Seo, ... The EMBO journal 36 (8), 1046-1065, 2017 | 71 | 2017 |
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, ... Journal of Neuroinflammation 17, 1-22, 2020 | 46 | 2020 |
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies S Lee, YM Jeon, SJ Cha, S Kim, Y Kwon, M Jo, YN Jang, S Lee, J Kim, ... Autophagy 16 (8), 1396-1412, 2020 | 43 | 2020 |
Imbalance of mitochondrial dynamics in Drosophila models of amyotrophic lateral sclerosis V Altanbyek, SJ Cha, GU Kang, S Lee, HJ Kim, K Kim Biochemical and biophysical research communications 481 (3-4), 259-264, 2016 | 42 | 2016 |
Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity CY Chung, A Berson, JR Kennerdell, A Sartoris, T Unger, S Porta, HJ Kim, ... Nature communications 9 (1), 4406, 2018 | 41 | 2018 |
Dietary restriction and neuroinflammation: a potential mechanistic link E Bok, M Jo, S Lee, BR Lee, J Kim, HJ Kim International journal of molecular sciences 20 (3), 464, 2019 | 39 | 2019 |
Drosophila Cand1 regulates Cullin3-dependent E3 ligases by affecting the neddylation of Cullin3 and by controlling the stability of Cullin3 and adaptor protein SH Kim, HJ Kim, S Kim, J Yim Developmental biology 346 (2), 247-257, 2010 | 34 | 2010 |
Neuroprotective effects of protein tyrosine phosphatase 1B inhibition against ER stress-induced toxicity YM Jeon, S Lee, S Kim, Y Kwon, K Kim, CG Chung, S Lee, SB Lee, ... Molecules and cells 40 (4), 280-290, 2017 | 33 | 2017 |
Drosophila homolog of APP-BP1 (dAPP-BP1) interacts antagonistically with APPL during Drosophila development HJ Kim, SH Kim, SO Shim, E Park, C Kim, K Kim, MA Tanouye, J Yim Cell Death & Differentiation 14 (1), 103-115, 2007 | 27 | 2007 |
Recent advances on the role of gsk3β in the pathogenesis of amyotrophic lateral sclerosis HJ Choi, SJ Cha, JW Lee, HJ Kim, K Kim Brain Sciences 10 (10), 675, 2020 | 26 | 2020 |
Beneficial effects of silibinin against kainic acid-induced neurotoxicity in the hippocampus in vivo S Kim, UJ Jung, YS Oh, MT Jeon, HJ Kim, WH Shin, J Hong, SR Kim Experimental Neurobiology 26 (5), 266, 2017 | 23 | 2017 |
Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3 JH Park, CG Chung, SS Park, D Lee, KM Kim, Y Jeong, ES Kim, JH Cho, ... Elife 9, e60132, 2020 | 21 | 2020 |