|Activation of STING requires palmitoylation at the Golgi|
K Mukai, H Konno, T Akiba, T Uemura, S Waguri, T Kobayashi, GN Barber, ...
Nature communications 7 (1), 11932, 2016
|Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes|
Y Uchida, J Hasegawa, D Chinnapen, T Inoue, S Okazaki, R Kato, ...
Proceedings of the National Academy of Sciences 108 (38), 15846-15851, 2011
|Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling|
AL Hansen, GJ Buchan, M Rühl, K Mukai, SR Salvatore, E Ogawa, ...
Proceedings of the National Academy of Sciences 115 (33), E7768-E7775, 2018
|Transport through recycling endosomes requires EHD 1 recruitment by a phosphatidylserine translocase|
S Lee, Y Uchida, J Wang, T Matsudaira, T Nakagawa, T Kishimoto, ...
The EMBO journal 34 (5), 669-688, 2015
|A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome|
Z Deng, Z Chong, CS Law, K Mukai, FO Ho, T Martinu, BJ Backes, ...
Journal of Experimental Medicine 217 (11), e20201045, 2020
|Innate immunity signalling and membrane trafficking|
T Taguchi, K Mukai
Current opinion in cell biology 59, 1-7, 2019
|Homeostatic regulation of STING by retrograde membrane traffic to the ER|
K Mukai, E Ogawa, R Uematsu, Y Kuchitsu, F Kiku, T Uemura, S Waguri, ...
Nature communications 12 (1), 61, 2021
|The binding of TBK1 to STING requires exocytic membrane traffic from the ER|
E Ogawa, K Mukai, K Saito, H Arai, T Taguchi
Biochemical and biophysical research communications 503 (1), 138-145, 2018
|STING palmitoylation as a therapeutic target|
AL Hansen, K Mukai, FJ Schopfer, T Taguchi, CK Holm
Cellular & molecular immunology 16 (3), 236-241, 2019
|STING operation at the ER/Golgi interface|
T Taguchi, K Mukai, E Takaya, R Shindo
Frontiers in immunology 12, 646304, 2021
|Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells|
T Matsudaira, K Mukai, T Noguchi, J Hasegawa, T Hatta, S Iemura, ...
Nature communications 8 (1), 1246, 2017
|STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes|
Y Kuchitsu, K Mukai, R Uematsu, Y Takaada, A Shinojima, R Shindo, ...
Nature Cell Biology 25 (3), 453-466, 2023
|Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation|
M Nishitani-Isa, K Mukai, Y Honda, H Nihira, T Tanaka, H Shibata, ...
Journal of Experimental Medicine 219 (6), e20211889, 2022
|A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation|
K Takahashi, T Niki, E Ogawa, K Fumika, Y Nishioka, M Sawa, H Arai, ...
Scientific reports 11 (1), 11996, 2021
|Homeostatic regulation of STING by Golgi-to-ER membrane traffic|
K Mukai, E Ogawa, R Uematsu, Y Kuchitsu, T Uemura, S Waguri, T Suzuki, ...
BioRxiv, 2020.05. 20.107664, 2020
|Specific association of TBK1 with the trans-Golgi network following STING stimulation|
H Kemmoku, Y Kuchitsu, K Mukai, T Taguchi
Cell structure and function 47 (1), 19-30, 2022
|Magnetic Separation of Autophagosomes from Mammalian Cells Using Magnetic–Plasmonic Hybrid Nanobeads|
M Takahashi, P Mohan, K Mukai, Y Takeda, T Matsumoto, K Matsumura, ...
ACS omega 2 (8), 4929-4937, 2017
|A role of phosphatidylserine in the function of recycling endosomes|
J Hasegawa, Y Uchida, K Mukai, S Lee, T Matsudaira, T Taguchi
Frontiers in Cell and Developmental Biology 9, 783857, 2021
|TLR7/8 stress response drives histiocytosis in SLC29A3 disorders|
T Shibata, R Sato, M Taoka, SI Saitoh, M Komine, K Yamaguchi, ...
Journal of Experimental Medicine 220 (9), e20230054, 2023
|The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation|
R Shindo, Y Kuchitsu, K Mukai, T Taguchi
Frontiers in Cell and Developmental Biology 10, 1037999, 2022