Activation of STING requires palmitoylation at the Golgi K Mukai, H Konno, T Akiba, T Uemura, S Waguri, T Kobayashi, GN Barber, ... Nature communications 7 (1), 11932, 2016 | 589 | 2016 |
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling AL Hansen, GJ Buchan, M Rühl, K Mukai, SR Salvatore, E Ogawa, ... Proceedings of the National Academy of Sciences 115 (33), E7768-E7775, 2018 | 218 | 2018 |
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes Y Uchida, J Hasegawa, D Chinnapen, T Inoue, S Okazaki, R Kato, ... Proceedings of the National Academy of Sciences 108 (38), 15846-15851, 2011 | 199 | 2011 |
A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome Z Deng, Z Chong, CS Law, K Mukai, FO Ho, T Martinu, BJ Backes, ... Journal of Experimental Medicine 217 (11), e20201045, 2020 | 155 | 2020 |
Transport through recycling endosomes requires EHD 1 recruitment by a phosphatidylserine translocase S Lee, Y Uchida, J Wang, T Matsudaira, T Nakagawa, T Kishimoto, ... The EMBO journal 34 (5), 669-688, 2015 | 134 | 2015 |
Innate immunity signalling and membrane trafficking T Taguchi, K Mukai Current opinion in cell biology 59, 1-7, 2019 | 116 | 2019 |
Homeostatic regulation of STING by retrograde membrane traffic to the ER K Mukai, E Ogawa, R Uematsu, Y Kuchitsu, F Kiku, T Uemura, S Waguri, ... Nature Communications 12 (1), 61, 2021 | 109 | 2021 |
The binding of TBK1 to STING requires exocytic membrane traffic from the ER E Ogawa, K Mukai, K Saito, H Arai, T Taguchi Biochemical and biophysical research communications 503 (1), 138-145, 2018 | 87 | 2018 |
STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes Y Kuchitsu, K Mukai, R Uematsu, Y Takaada, A Shinojima, R Shindo, ... Nature Cell Biology 25 (3), 453-466, 2023 | 73 | 2023 |
STING palmitoylation as a therapeutic target AL Hansen, K Mukai, FJ Schopfer, T Taguchi, CK Holm Cellular & molecular immunology 16 (3), 236-241, 2019 | 67 | 2019 |
STING operation at the ER/Golgi interface T Taguchi, K Mukai, E Takaya, R Shindo Frontiers in immunology 12, 646304, 2021 | 61 | 2021 |
Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells T Matsudaira, K Mukai, T Noguchi, J Hasegawa, T Hatta, S Iemura, ... Nature communications 8 (1), 1246, 2017 | 46 | 2017 |
Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation M Nishitani-Isa, K Mukai, Y Honda, H Nihira, T Tanaka, H Shibata, ... Journal of Experimental Medicine 219 (6), e20211889, 2022 | 30 | 2022 |
Specific association of TBK1 with the trans-Golgi network following STING stimulation H Kemmoku, Y Kuchitsu, K Mukai, T Taguchi Cell Structure and Function 47 (1), 19-30, 2022 | 17 | 2022 |
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation K Takahashi, T Niki, E Ogawa, K Fumika, Y Nishioka, M Sawa, H Arai, ... Scientific Reports 11 (1), 11996, 2021 | 17 | 2021 |
Homeostatic regulation of STING by Golgi-to-ER membrane traffic K Mukai, E Ogawa, R Uematsu, Y Kuchitsu, T Uemura, S Waguri, T Suzuki, ... BioRxiv, 2020.05. 20.107664, 2020 | 16 | 2020 |
Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol H Kemmoku, K Takahashi, K Mukai, T Mori, KM Hirosawa, F Kiku, ... Nature Communications 15 (1), 220, 2024 | 13 | 2024 |
A role of phosphatidylserine in the function of recycling endosomes J Hasegawa, Y Uchida, K Mukai, S Lee, T Matsudaira, T Taguchi Frontiers in Cell and Developmental Biology 9, 783857, 2021 | 12 | 2021 |
Magnetic Separation of Autophagosomes from Mammalian Cells Using Magnetic–Plasmonic Hybrid Nanobeads M Takahashi, P Mohan, K Mukai, Y Takeda, T Matsumoto, K Matsumura, ... ACS omega 2 (8), 4929-4937, 2017 | 9 | 2017 |
TLR7/8 stress response drives histiocytosis in SLC29A3 disorders T Shibata, R Sato, M Taoka, SI Saitoh, M Komine, K Yamaguchi, ... Journal of Experimental Medicine 220 (9), e20230054, 2023 | 8 | 2023 |