| α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A β-amyloid-induced neurotoxicity T Kihara, S Shimohama, H Sawada, K Honda, T Nakamizo, H Shibasaki, ... Journal of Biological Chemistry 276 (17), 13541-13546, 2001 | 508 | 2001 |
| Nicotinic receptor stimulation protects neurons against β‐amyloid toxicity T Kihara, S Shimohama, H Sawada, J Kimura, T Kume, H Kochiyama, ... Annals of Neurology: Official Journal of the American Neurological …, 1997 | 424 | 1997 |
| Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia? A Nishiyori, M Minami, Y Ohtani, S Takami, J Yamamoto, N Kawaguchi, ... FEBS letters 429 (2), 167-172, 1998 | 394 | 1998 |
| Protective effects of 1α, 25-(OH) 2D3 against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture M Ibi, H Sawada, M Nakanishi, T Kume, H Katsuki, S Kaneko, ... Neuropharmacology 40 (6), 761-771, 2001 | 305 | 2001 |
| Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons Y Takada, A Yonezawa, T Kume, H Katsuki, S Kaneko, H Sugimoto, ... Journal of Pharmacology and Experimental Therapeutics 306 (2), 772-777, 2003 | 262 | 2003 |
| A critical role of TRPM2 in neuronal cell death by hydrogen peroxide S Kaneko, S Kawakami, Y Hara, M Wakamori, E Itoh, T Minami, Y Takada, ... Journal of pharmacological sciences 101 (1), 66-76, 2006 | 251 | 2006 |
| Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via α7-neuronal receptors and neuronal CNS receptors S Kaneko, T Maeda, T Kume, H Kochiyama, A Akaike, S Shimohama, ... Brain research 765 (1), 135-140, 1997 | 251 | 1997 |
| Stimulation of α4β2 nicotinic acetylcholine receptors inhibits β-amyloid toxicity T Kihara, S Shimohama, M Urushitani, H Sawada, J Kimura, T Kume, ... Brain research 792 (2), 331-334, 1998 | 249 | 1998 |
| Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults M Okawara, H Katsuki, E Kurimoto, H Shibata, T Kume, A Akaike Biochemical pharmacology 73 (4), 550-560, 2007 | 246 | 2007 |
| Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase … Y Takada-Takatori, T Kume, M Sugimoto, H Katsuki, H Sugimoto, ... Neuropharmacology 51 (3), 474-486, 2006 | 232 | 2006 |
| Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of α4 and α7 receptors in neuroprotection A Akaike, Y Takada-Takatori, T Kume, Y Izumi Journal of Molecular Neuroscience 40, 211-216, 2010 | 222 | 2010 |
| Differential neurotoxicity induced by L-DOPA and dopamine in cultured striatal neurons N Cheng, T Maeda, T Kume, S Kaneko, H Kochiyama, A Akaike, ... Brain research 743 (1-2), 278-283, 1996 | 193 | 1996 |
| α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons F Osakada, A Hashino, T Kume, H Katsuki, S Kaneko, A Akaike Neuropharmacology 47 (6), 904-915, 2004 | 180 | 2004 |
| Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease N Yamamoto, H Sawada, Y Izumi, T Kume, H Katsuki, S Shimohama, ... Journal of Biological Chemistry 282 (7), 4364-4372, 2007 | 168 | 2007 |
| Mechanism of the pathogenesis of glutamate neurotoxicity in retinal ischemia K Adachi, S Kashii, H Masai, M Ueda, C Morizane, K Kaneda, T Kume, ... Graefe's archive for clinical and experimental ophthalmology 236, 766-774, 1998 | 155 | 1998 |
| p‐quinone mediates 6‐hydroxydopamine‐induced dopaminergic neuronal death and ferrous iron accelerates the conversion of p‐quinone into melanin … Y Izumi, H Sawada, N Sakka, N Yamamoto, T Kume, H Katsuki, ... Journal of neuroscience research 79 (6), 849-860, 2005 | 146 | 2005 |
| HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats M Ohnishi, H Katsuki, C Fukutomi, M Takahashi, M Motomura, ... Neuropharmacology 61 (5-6), 975-980, 2011 | 140 | 2011 |
| Endogenous D-serine is involved in induction of neuronal death by N-methyl-D-aspartate and simulated ischemia in rat cerebrocortical slices H Katsuki, M Nonaka, H Shirakawa, T Kume, A Akaike Journal of Pharmacology and Experimental Therapeutics 311 (2), 836-844, 2004 | 126 | 2004 |
| Protective effect of aminoguanidine on hypoxic-ischemic brain damage and temporal profile of brain nitric oxide in neonatal rat M Tsuji, Y Higuchi, K Shiraishi, T Kume, A Akaike, H Hattori Pediatric research 47 (1), 79-79, 2000 | 126 | 2000 |
| Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury M Ohnishi, H Katsuki, S Fujimoto, M Takagi, T Kume, A Akaike Experimental neurology 206 (1), 43-52, 2007 | 117 | 2007 |
