| Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ... Cell 152 (5), 1173-1183, 2013 | 3581 | 2013 |
| CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ... Cell 154 (2), 442-451, 2013 | 2697 | 2013 |
| Genome-scale CRISPR-mediated control of gene repression and activation LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ... Cell 159 (3), 647-661, 2014 | 1664 | 2014 |
| Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system B Chen, LA Gilbert, BA Cimini, J Schnitzbauer, W Zhang, GW Li, J Park, ... Cell 155 (7), 1479-1491, 2013 | 1515 | 2013 |
| A protein-tagging system for signal amplification in gene expression and fluorescence imaging ME Tanenbaum, LA Gilbert, LS Qi, JS Weissman, RD Vale Cell 159 (3), 635-646, 2014 | 941 | 2014 |
| CRISPR interference (CRISPRi) for sequence-specific control of gene expression MH Larson, LA Gilbert, X Wang, WA Lim, JS Weissman, LS Qi Nature protocols 8 (11), 2180-2196, 2013 | 828 | 2013 |
| Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds JG Zalatan, ME Lee, R Almeida, LA Gilbert, EH Whitehead, M La Russa, ... Cell 160 (1-2), 339-350, 2015 | 727 | 2015 |
| A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response B Adamson, TM Norman, M Jost, MY Cho, JK Nuñez, Y Chen, JE Villalta, ... Cell 167 (7), 1867-1882. e21, 2016 | 503 | 2016 |
| CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells SJ Liu, MA Horlbeck, SW Cho, HS Birk, M Malatesta, D He, FJ Attenello, ... Science 355 (6320), 2017 | 425 | 2017 |
| DNA damage-mediated induction of a chemoresistant niche LA Gilbert, MT Hemann Cell 143 (3), 355-366, 2010 | 401 | 2010 |
| Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ... Elife 5, e19760, 2016 | 346 | 2016 |
| Nucleosomes impede Cas9 access to DNA in vivo and in vitro MA Horlbeck, LB Witkowsky, B Guglielmi, JM Replogle, LA Gilbert, ... elife 5, e12677, 2016 | 279 | 2016 |
| CRISPR interference efficiently induces specific and reversible gene silencing in human iPSCs MA Mandegar, N Huebsch, EB Frolov, E Shin, A Truong, MP Olvera, ... Cell stem cell 18 (4), 541-553, 2016 | 278 | 2016 |
| Genomic hallmarks and structural variation in metastatic prostate cancer DA Quigley, HX Dang, SG Zhao, P Lloyd, R Aggarwal, JJ Alumkal, A Foye, ... Cell 174 (3), 758-769. e9, 2018 | 268 | 2018 |
| Versatile protein tagging in cells with split fluorescent protein D Kamiyama, S Sekine, B Barsi-Rhyne, J Hu, B Chen, LA Gilbert, ... Nature communications 7 (1), 1-9, 2016 | 226 | 2016 |
| Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells LA Gilbert, S Ravindran, JM Turetzky, JC Boothroyd, PJ Bradley Eukaryotic cell 6 (1), 73-83, 2007 | 190 | 2007 |
| Defining principles of combination drug mechanisms of action JR Pritchard, PM Bruno, LA Gilbert, KL Capron, DA Lauffenburger, ... Proceedings of the National Academy of Sciences 110 (2), E170-E179, 2013 | 141 | 2013 |
| Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification RM Deans, DW Morgens, A Ökesli, S Pillay, MA Horlbeck, M Kampmann, ... Nature chemical biology 12 (5), 361-366, 2016 | 124 | 2016 |
| Mapping the genetic landscape of human cells MA Horlbeck, A Xu, M Wang, NK Bennett, CY Park, D Bogdanoff, ... Cell 174 (4), 953-967. e22, 2018 | 122 | 2018 |
| Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular cell 68 (1), 210-223. e6, 2017 | 116 | 2017 |
Jonathan S. WeissmanUCSF/HHMIVerified email at ucsf.edu
