Luke Gilbert
Luke Gilbert
Assistant Professor at UCSF
Verified email at ucsf.edu
Title
Cited by
Cited by
Year
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ...
Cell 152 (5), 1173-1183, 2013
35812013
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ...
Cell 154 (2), 442-451, 2013
26972013
Genome-scale CRISPR-mediated control of gene repression and activation
LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ...
Cell 159 (3), 647-661, 2014
16642014
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system
B Chen, LA Gilbert, BA Cimini, J Schnitzbauer, W Zhang, GW Li, J Park, ...
Cell 155 (7), 1479-1491, 2013
15152013
A protein-tagging system for signal amplification in gene expression and fluorescence imaging
ME Tanenbaum, LA Gilbert, LS Qi, JS Weissman, RD Vale
Cell 159 (3), 635-646, 2014
9412014
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
MH Larson, LA Gilbert, X Wang, WA Lim, JS Weissman, LS Qi
Nature protocols 8 (11), 2180-2196, 2013
8282013
Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds
JG Zalatan, ME Lee, R Almeida, LA Gilbert, EH Whitehead, M La Russa, ...
Cell 160 (1-2), 339-350, 2015
7272015
A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response
B Adamson, TM Norman, M Jost, MY Cho, JK Nu˝ez, Y Chen, JE Villalta, ...
Cell 167 (7), 1867-1882. e21, 2016
5032016
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
SJ Liu, MA Horlbeck, SW Cho, HS Birk, M Malatesta, D He, FJ Attenello, ...
Science 355 (6320), 2017
4252017
DNA damage-mediated induction of a chemoresistant niche
LA Gilbert, MT Hemann
Cell 143 (3), 355-366, 2010
4012010
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ...
Elife 5, e19760, 2016
3462016
Nucleosomes impede Cas9 access to DNA in vivo and in vitro
MA Horlbeck, LB Witkowsky, B Guglielmi, JM Replogle, LA Gilbert, ...
elife 5, e12677, 2016
2792016
CRISPR interference efficiently induces specific and reversible gene silencing in human iPSCs
MA Mandegar, N Huebsch, EB Frolov, E Shin, A Truong, MP Olvera, ...
Cell stem cell 18 (4), 541-553, 2016
2782016
Genomic hallmarks and structural variation in metastatic prostate cancer
DA Quigley, HX Dang, SG Zhao, P Lloyd, R Aggarwal, JJ Alumkal, A Foye, ...
Cell 174 (3), 758-769. e9, 2018
2682018
Versatile protein tagging in cells with split fluorescent protein
D Kamiyama, S Sekine, B Barsi-Rhyne, J Hu, B Chen, LA Gilbert, ...
Nature communications 7 (1), 1-9, 2016
2262016
Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells
LA Gilbert, S Ravindran, JM Turetzky, JC Boothroyd, PJ Bradley
Eukaryotic cell 6 (1), 73-83, 2007
1902007
Defining principles of combination drug mechanisms of action
JR Pritchard, PM Bruno, LA Gilbert, KL Capron, DA Lauffenburger, ...
Proceedings of the National Academy of Sciences 110 (2), E170-E179, 2013
1412013
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
RM Deans, DW Morgens, A Íkesli, S Pillay, MA Horlbeck, M Kampmann, ...
Nature chemical biology 12 (5), 361-366, 2016
1242016
Mapping the genetic landscape of human cells
MA Horlbeck, A Xu, M Wang, NK Bennett, CY Park, D Bogdanoff, ...
Cell 174 (4), 953-967. e22, 2018
1222018
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ...
Molecular cell 68 (1), 210-223. e6, 2017
1162017
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Articles 1–20