MicroRNA‐494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer L Lim, A Balakrishnan, N Huskey, KD Jones, M Jodari, R Ng, G Song, ... Hepatology 59 (1), 202-215, 2014 | 137 | 2014 |
From peas to disease: modifier genes, network resilience, and the genetics of health JD Riordan, JH Nadeau The American Journal of Human Genetics 101 (2), 177-191, 2017 | 125 | 2017 |
Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis JD Riordan, VW Keng, BR Tschida, TE Scheetz, JB Bell, ... PLoS genetics 9 (4), e1003441, 2013 | 122 | 2013 |
The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis D DeZwaan-McCabe, JD Riordan, AM Arensdorf, MS Icardi, AJ Dupuy, ... PLoS genetics 9 (12), e1003937, 2013 | 85 | 2013 |
Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR VW Keng, D Sia, AL Sarver, BR Tschida, D Fan, C Alsinet, M Solé, ... Hepatology 57 (1), 120-130, 2013 | 67 | 2013 |
Modeling progressive non-alcoholic fatty liver disease in the laboratory mouse JD Riordan, JH Nadeau Mammalian genome 25, 473-486, 2014 | 43 | 2014 |
Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice JD Riordan, CR Feddersen, BR Tschida, PJ Beckmann, VW Keng, ... Hepatology 67 (3), 924-939, 2018 | 41 | 2018 |
Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors BR Tschida, NA Temiz, TP Kuka, LA Lee, JD Riordan, CA Tierrablanca, ... Cancer research 77 (23), 6576-6588, 2017 | 39 | 2017 |
Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver V Blanc, Y Xie, S Kennedy, JD Riordan, DC Rubin, BB Madison, JC Mills, ... Rna 25 (1), 70-81, 2019 | 38 | 2019 |
RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens NA Temiz, BS Moriarity, NK Wolf, JD Riordan, AJ Dupuy, ... Genome research 26 (1), 119-129, 2016 | 37 | 2016 |
A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model N Zanesi, V Balatti, J Riordan, A Burch, L Rizzotto, A Palamarchuk, ... Blood, The Journal of the American Society of Hematology 121 (21), 4355-4358, 2013 | 37 | 2013 |
Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancer LM Rogers, JD Riordan, BL Swick, DK Meyerholz, AJ Dupuy Journal of investigative dermatology 133 (7), 1863-1869, 2013 | 32 | 2013 |
Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome DS Sinasac, JD Riordan, SH Spiezio, BS Yandell, CM Croniger, ... International Journal of Obesity 40 (2), 346-355, 2016 | 30 | 2016 |
Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens JD Riordan, LJ Drury, RP Smith, BT Brett, LM Rogers, TE Scheetz, ... BMC genomics 15, 1-15, 2014 | 30 | 2014 |
Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer V Blanc, JD Riordan, S Soleymanjahi, JH Nadeau, ILK Nalbantoglu, Y Xie, ... The Journal of clinical investigation 131 (1), 2021 | 26 | 2021 |
Src-dependent DBL family members drive resistance to vemurafenib in human melanoma CR Feddersen, JL Schillo, A Varzavand, HR Vaughn, LS Wadsworth, ... Cancer research 79 (19), 5074-5087, 2019 | 20 | 2019 |
Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene C Montero-Conde, LJ Leandro-Garcia, X Chen, G Oler, S Ruiz-Llorente, ... Proceedings of the National Academy of Sciences 114 (25), E4951-E4960, 2017 | 20 | 2017 |
Domesticated transposable element gene products in human cancer JD Riordan, AJ Dupuy Mobile genetic elements 3 (5), e26693, 2013 | 19 | 2013 |
A forward genetic screen targeting the endothelium reveals a regulatory role for the lipid kinase Pi4ka in myelo-and erythropoiesis S Ziyad, JD Riordan, AM Cavanaugh, T Su, GE Hernandez, G Hilfenhaus, ... Cell reports 22 (5), 1211-1224, 2018 | 16 | 2018 |
A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition RP Smith, JD Riordan, CR Feddersen, AJ Dupuy Human gene therapy 26 (6), 377-385, 2015 | 14 | 2015 |