フォロー
Tara Man Kadayat, Ph.D.
Tara Man Kadayat, Ph.D.
Medicinal Chemist/Postdoctoral Scholar at University of Kentucky College of Pharmacy
確認したメール アドレス: uky.edu - ホームページ
タイトル
引用先
引用先
A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases
HB Kwon, C Park, KH Jeon, E Lee, SE Park, KY Jun, TM Kadayat, ...
Journal of Medicinal Chemistry 58 (3), 1100-1122, 2015
1002015
Design, synthesis, and antitumor evaluation of 2, 4, 6-triaryl pyridines containing chlorophenyl and phenolic moiety
P Thapa, R Karki, M Yun, TM Kadayat, E Lee, HB Kwon, Y Na, WJ Cho, ...
European journal of medicinal chemistry 52, 123-136, 2012
762012
Dihydroxylated 2, 4, 6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study
R Karki, P Thapa, HY Yoo, TM Kadayat, PH Park, Y Na, E Lee, KH Jeon, ...
European journal of medicinal chemistry 49, 219-228, 2012
722012
Discovery and structure-activity relationship studies of 2-benzylidene-2, 3-dihydro-1H-inden-1-one and benzofuran-3 (2H)-one derivatives as a novel class of potential …
TM Kadayat, S Banskota, P Gurung, G Bist, TBT Magar, A Shrestha, ...
European Journal of Medicinal Chemistry 137, 575-597, 2017
442017
Hydroxylated 2, 4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor
TM Kadayat, C Park, KY Jun, TBT Magar, G Bist, HY Yoo, Y Kwon, ES Lee
European Journal of Medicinal Chemistry 90, 302-314, 2015
412015
Topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of dihydroxylated 2, 6-diphenyl-4-aryl pyridines
R Karki, C Song, TM Kadayat, TBT Magar, G Bist, A Shrestha, Y Na, ...
Bioorganic & medicinal chemistry 23 (13), 3638-3654, 2015
372015
Synthesis, antitumor activity, and structure–activity relationship study of trihydroxylated 2, 4, 6-triphenyl pyridines as potent and selective topoisomerase II inhibitors
R Karki, C Park, KY Jun, JG Jee, JH Lee, P Thapa, TM Kadayat, Y Kwon, ...
European journal of medicinal chemistry 84, 555-565, 2014
372014
Synthesis and biological activity of 2, 4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison
R Karki, C Park, KY Jun, TM Kadayat, ES Lee, Y Kwon
European Journal of Medicinal Chemistry 90, 360-378, 2015
332015
Rational design, synthesis, and evaluation of novel 2, 4-Chloro-and Hydroxy-Substituted diphenyl Benzofuro [3, 2-b] Pyridines: Non-intercalative catalytic topoisomerase I and …
S Park, TBT Magar, TM Kadayat, HJ Lee, G Bist, A Shrestha, ES Lee, ...
European Journal of Medicinal Chemistry 127, 318-333, 2017
322017
Novel 2-aryl-4-(4′-hydroxyphenyl)-5H-indeno [1, 2-b] pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors
S Park, TM Kadayat, KY Jun, TBT Magar, G Bist, A Shrestha, ES Lee, ...
European journal of medicinal chemistry 125, 14-28, 2017
302017
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of 2-phenyl-or hydroxylated 2-phenyl-4-aryl-5H-indeno [1, 2-b …
TM Kadayat, C Song, S Shin, TBT Magar, G Bist, A Shrestha, P Thapa, ...
Bioorganic & Medicinal Chemistry 23 (13), 3499-3512, 2015
282015
Design and synthesis of novel 2, 4-diaryl-5H-indeno [1, 2-b] pyridine derivatives, and their evaluation of topoisomerase inhibitory activity and cytotoxicity
TM Kadayat, C Park, KY Jun, TBT Magar, G Bist, HY Yoo, Y Kwon, ES Lee
Bioorganic & Medicinal Chemistry 23 (1), 160-173, 2015
282015
Modified 2, 4-diaryl-5H-indeno [1, 2-b] pyridines with hydroxyl and chlorine moiety: synthesis, anticancer activity, and structure–activity relationship study
TM Kadayat, C Song, Y Kwon, ES Lee
Bioorganic Chemistry 62, 30-40, 2015
272015
Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents
P Thapa, KY Jun, TM Kadayat, C Park, Z Zheng, TBT Magar, G Bist, ...
Bioorganic & Medicinal Chemistry 23 (19), 6454-6466, 2015
262015
Synthesis and SAR study of new hydroxy and chloro-substituted 2, 4-diphenyl 5H-chromeno [4, 3-b] pyridines as selective topoisomerase IIα-targeting anticancer agents
TBT Magar, SH Seo, TM Kadayat, H Jo, A Shrestha, G Bist, P Katila, ...
Bioorganic & medicinal chemistry 26 (8), 1909-1919, 2018
242018
Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-b]pyridinol Derivatives as Potent Topoisomerase IIα-Targeted Chemotherapeutic …
TM Kadayat, S Park, A Shrestha, H Jo, SY Hwang, P Katila, R Shrestha, ...
Journal of Medicinal Chemistry 62 (17), 8194-8234, 2019
232019
2-Chlorophenyl-substituted benzofuro [3, 2-b] pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent
TBT Magar, TM Kadayat, HJ Lee, S Park, G Bist, A Shrestha, Y Kwon, ...
Bioorganic & Medicinal Chemistry Letters 27 (15), 3279-3283, 2017
232017
A novel indeno [1, 2-b] pyridinone derivative, a DNA intercalative human topoisomerase IIα catalytic inhibitor, for caspase 3-independent anticancer activity
KH Jeon, C Park, TM Kadayat, A Shrestha, ES Lee, Y Kwon
Chemical communications 53 (51), 6864-6867, 2017
212017
A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study
R Karki, KY Jun, TM Kadayat, S Shin, TBT Magar, G Bist, A Shrestha, ...
European Journal of Medicinal Chemistry 113, 228-245, 2016
212016
Patterns and perception of complementary and alternative medicine use by patients in western Nepal
N Kadayat, Tara Man, Bist Ganesh, Parajuli, Anirudra, Karki Renu ...
Journal of Public Health 20 (3), 297-303, 2012
192012
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