| Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies MI Veiga, SK Dhingra, PP Henrich, J Straimer, N Gnädig, AC Uhlemann, ... Nature communications 7 (1), 11553, 2016 | 264 | 2016 |
| Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine LS Ross, SK Dhingra, S Mok, T Yeo, KJ Wicht, K Kümpornsin, ... Nature communications 9 (1), 3314, 2018 | 204 | 2018 |
| Structure and drug resistance of the Plasmodium falciparum transporter PfCRT J Kim, YZ Tan, KJ Wicht, SK Erramilli, SK Dhingra, J Okombo, J Vendome, ... Nature 576 (7786), 315-320, 2019 | 153 | 2019 |
| Adaptive evolution of malaria parasites in French Guiana: reversal of chloroquine resistance by acquisition of a mutation in pfcrt S Pelleau, EL Moss, SK Dhingra, B Volney, J Casteras, SJ Gabryszewski, ... Proceedings of the National Academy of Sciences 112 (37), 11672-11677, 2015 | 130 | 2015 |
| Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness BH Stokes, SK Dhingra, K Rubiano, S Mok, J Straimer, NF Gnädig, I Deni, ... Elife 10, e66277, 2021 | 102 | 2021 |
| A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine SK Dhingra, D Redhi, JM Combrinck, T Yeo, J Okombo, PP Henrich, ... MBio 8 (3), 10.1128/mbio. 00303-17, 2017 | 98 | 2017 |
| Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter I Petersen, SJ Gabryszewski, GL Johnston, SK Dhingra, A Ecker, ... Molecular microbiology 97 (2), 381-395, 2015 | 68 | 2015 |
| Plasmodium falciparum resistance to piperaquine driven by PfCRT SK Dhingra, JL Small-Saunders, D Ménard, DA Fidock The Lancet Infectious Diseases 19 (11), 1168-1169, 2019 | 60 | 2019 |
| Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the … J White, SK Dhingra, X Deng, F El Mazouni, MCS Lee, GA Afanador, ... ACS infectious diseases 5 (1), 90-101, 2018 | 49 | 2018 |
| Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and … SJ Gabryszewski, SK Dhingra, JM Combrinck, IA Lewis, PS Callaghan, ... PLoS pathogens 12 (11), e1005976, 2016 | 46 | 2016 |
| Global spread of mutant PfCRT and its pleiotropic impact on Plasmodium falciparum multidrug resistance and fitness SK Dhingra, SJ Gabryszewski, JL Small-Saunders, T Yeo, PP Henrich, ... MBio 10 (2), 10.1128/mbio. 02731-18, 2019 | 40 | 2019 |
| Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo … JS McCarthy, Ö Yalkinoglu, A Odedra, R Webster, C Oeuvray, A Tappert, ... The Lancet Infectious Diseases 21 (12), 1713-1724, 2021 | 35 | 2021 |
| Preclinical antimalarial combination study of M5717, a Plasmodium falciparum elongation factor 2 inhibitor, and pyronaridine, a hemozoin formation inhibitor M Rottmann, B Jonat, C Gumpp, SK Dhingra, MJ Giddins, X Yin, L Badolo, ... Antimicrobial agents and chemotherapy 64 (4), 10.1128/aac. 02181-19, 2020 | 33 | 2020 |
| Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter AH Lee, SK Dhingra, IA Lewis, MK Singh, A Siriwardana, S Dalal, ... Scientific reports 8 (1), 13578, 2018 | 32 | 2018 |
| Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance JL Small-Saunders, LM Hagenah, KJ Wicht, SK Dhingra, I Deni, J Kim, ... PLoS Pathogens 18 (2), e1010278, 2022 | 16 | 2022 |
| Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine. Nat Commun. 2018; 9: 3314 LS Ross, SK Dhingra, S Mok, T Yeo, KJ Wicht, K Kumpornsin | 10 | |
| Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine KE Ward, P Christensen, A Racklyeft, SK Dhingra, ACY Chua, C Remmert, ... The Journal of infectious diseases 227 (10), 1121-1126, 2023 | 6 | 2023 |
| Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness S Mok, T Yeo, D Hong, MJ Shears, LS Ross, KE Ward, SK Dhingra, ... Science Advances 9 (45), eadi2364, 2023 | 5 | 2023 |
| Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in … JL van der Plas, VP Kuiper, WM Bagchus, M Bödding, Ö Yalkinoglu, ... The Lancet Infectious Diseases 23 (10), 1164-1174, 2023 | 5 | 2023 |
| Structure and drug resistance of the plasmodium Falciparum transporter PfCRT J Kim, YZ Tan, KJ Wicht, SK Erramilli, SK Dhingra, J Okombo, ... Biophysical Journal 118 (3), 523a, 2020 | 2 | 2020 |
