Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin A Roll-Mecak, RD Vale Nature 451 (7176), 363-367, 2008 | 396 | 2008 |
Microtubule-severing enzymes A Roll-Mecak, FJ McNally Current opinion in cell biology 22 (1), 96-103, 2010 | 364 | 2010 |
X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding A Roll-Mecak, C Cao, TE Dever, SK Burley Cell 103 (5), 781-792, 2000 | 284 | 2000 |
Graded control of microtubule severing by tubulin glutamylation ML Valenstein, A Roll-Mecak Cell 164 (5), 911-921, 2016 | 263 | 2016 |
Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase A Szyk, AM Deaconescu, J Spector, B Goodman, ML Valenstein, ... Cell 157 (6), 1405-1415, 2014 | 252 | 2014 |
The tubulin code in microtubule dynamics and information encoding A Roll-Mecak Developmental cell 54 (1), 7-20, 2020 | 241 | 2020 |
The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules A Roll-Mecak, RD Vale Current biology 15 (7), 650-655, 2005 | 240 | 2005 |
Writing and reading the tubulin code I Yu, CP Garnham, A Roll-Mecak Journal of Biological Chemistry 290 (28), 17163-17172, 2015 | 235 | 2015 |
Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation A Vemu, E Szczesna, EA Zehr, JO Spector, N Grigorieff, AM Deaconescu, ... Science 361 (6404), eaau1504, 2018 | 222 | 2018 |
The chemical complexity of cellular microtubules: tubulin post‐translational modification enzymes and their roles in tuning microtubule functions CP Garnham, A Roll‐Mecak Cytoskeleton 69 (7), 442-463, 2012 | 204 | 2012 |
Tubulin isoform composition tunes microtubule dynamics A Vemu, J Atherton, JO Spector, CA Moores, A Roll-Mecak Molecular biology of the cell 28 (25), 3564-3572, 2017 | 190 | 2017 |
Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity BS Shin, D Maag, A Roll-Mecak, MS Arefin, SK Burley, JR Lorsch, ... Cell 111 (7), 1015-1025, 2002 | 176 | 2002 |
Microtubule-severing enzymes: From cellular functions to molecular mechanism FJ McNally, A Roll-Mecak Journal of Cell Biology 217 (12), 4057-4069, 2018 | 175 | 2018 |
Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin A Szyk, AM Deaconescu, G Piszczek, A Roll-Mecak Nature structural & molecular biology 18 (11), 1250-1258, 2011 | 161 | 2011 |
Structural basis for autoinhibition and mutational activation of eukaryotic initiation factor 2α protein kinase GCN2*[boxs] AK Padyana, H Qiu, A Roll-Mecak, AG Hinnebusch, SK Burley Journal of Biological Chemistry 280 (32), 29289-29299, 2005 | 143 | 2005 |
Universal conservation in translation initiation revealed by human and archaeal homologs of bacterial translation initiation factor IF2 JH Lee, SK Choi, A Roll-Mecak, SK Burley, TE Dever Proceedings of the National Academy of Sciences 96 (8), 4342-4347, 1999 | 133 | 1999 |
Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin*♦ A Vemu, J Atherton, JO Spector, A Szyk, CA Moores, A Roll-Mecak Journal of Biological Chemistry 291 (25), 12907-12915, 2016 | 128 | 2016 |
Intrinsically disordered tubulin tails: complex tuners of microtubule functions? A Roll-Mecak Seminars in cell & developmental biology 37, 11-19, 2015 | 126 | 2015 |
Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations X Sun, JH Park, J Gumerson, Z Wu, A Swaroop, H Qian, A Roll-Mecak, ... Proceedings of the National Academy of Sciences 113 (21), E2925-E2934, 2016 | 123 | 2016 |
Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2 SK Choi, DAS Olsen, A Roll-Mecak, A Martung, KL Remo, SK Burley, ... Molecular and cellular biology, 2000 | 118 | 2000 |