フォロー
Sachel Mok
Sachel Mok
Columbia University Irving Medical Center
確認したメール アドレス: cumc.columbia.edu
タイトル
引用先
引用先
Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
S Mok, EA Ashley, PE Ferreira, L Zhu, Z Lin, T Yeo, K Chotivanich, ...
Science 347 (6220), 431-435, 2015
4832015
Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance
C Dogovski, SC Xie, G Burgio, J Bridgford, S Mok, JM McCaw, ...
PLoS biology 13 (4), e1002132, 2015
3412015
The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites
Z Bozdech, S Mok, G Hu, M Imwong, A Jaidee, B Russell, H Ginsburg, ...
Proceedings of the National Academy of Sciences 105 (42), 16290-16295, 2008
2882008
Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum
G Hu, A Cabrera, M Kono, S Mok, BK Chaal, S Haase, K Engelberg, ...
Nature biotechnology 28 (1), 91-98, 2010
2622010
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells
A Claessens, Y Adams, A Ghumra, G Lindergard, CC Buchan, C Andisi, ...
Proceedings of the National Academy of Sciences 109 (26), E1772-E1781, 2012
2542012
Transcriptional variation in the malaria parasite Plasmodium falciparum
N Rovira-Graells, AP Gupta, E Planet, VM Crowley, S Mok, ...
Genome Research 22 (5), 925-938, 2012
2532012
Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine
LS Ross, SK Dhingra, S Mok, T Yeo, KJ Wicht, K Kümpornsin, ...
Nature Communications 9 (1), 3314, 2018
2042018
Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription
S Mok, M Imwong, MJ Mackinnon, J Sim, R Ramadoss, P Yi, M Mayxay, ...
BMC genomics 12 (1), 1, 2011
1932011
Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria
KJ Wicht, S Mok, DA Fidock
Annual Review of Microbiology 74, 431-454, 2020
1712020
Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites.
F Rocamora, L Zhu, KY Liong, A Dondorp, O Miotto, S Mok, Z Bozdech
PLoS pathogens 14 (3), e1006930, 2018
1582018
Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites
BJ Foth, N Zhang, S Mok, PR Preiser, Z Bozdech
Genome biology 9 (12), 1, 2008
1342008
Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance
LC Mathieu, H Cox, AM Early, S Mok, Y Lazrek, JC Paquet, MP Ade, ...
Elife 9, e51015, 2020
1212020
Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum
AP Gupta, WH Chin, L Zhu, S Mok, YH Luah, EH Lim, Z Bozdech
PLoS Pathog 9 (2), e1003170, 2013
1212013
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness
BH Stokes, SK Dhingra, K Rubiano, S Mok, J Straimer, NF Gnadig, I Deni, ...
eLife 10, e66277, 2021
1032021
Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates
MJ Mackinnon, J Li, S Mok, MM Kortok, K Marsh, PR Preiser, Z Bozdech
PLoS pathogens 5 (10), e1000644, 2009
1032009
A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine
SK Dhingra, D Redhi, JM Combrinck, T Yeo, J Okombo, PP Henrich, ...
mBio 8 (3), e00303-17, 2017
982017
Artemisinin-resistant K13 mutations rewire Plasmodium falciparums intra-erythrocytic metabolic program to enhance survival
S Mok, BH Stokes, NF Gnädig, LS Ross, T Yeo, C Amaratunga, E Allman, ...
Nature communications 12 (1), 530, 2021
952021
New insights into the Plasmodium vivax transcriptome using RNA-Seq
L Zhu, S Mok, M Imwong, A Jaidee, B Russell, F Nosten, NP Day, ...
Scientific reports 6 (1), 20498, 2016
802016
Adaptation of Plasmodium falciparum to its transmission environment
MK Rono, MA Nyonda, JJ Simam, JM Ngoi, S Mok, MM Kortok, ...
Nature ecology & evolution 2 (2), 377-387, 2018
772018
Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13
NF Gnädig, BH Stokes, RL Edwards, GF Kalantarov, KC Heimsch, ...
PLoS Pathogens 16 (4), e1008482, 2020
662020
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