| Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia WJ Song, MG Sullivan, RD Legare, S Hutchings, X Tan, D Kufrin, ... Nature genetics 23 (2), 166-175, 1999 | 1250 | 1999 |
| The CBFβ subunit is essential for CBFα2 (AML1) function in vivo Q Wang, T Stacy, JD Miller, AF Lewis, TL Gu, X Huang, JH Bushweller, ... Cell 87 (4), 697-708, 1996 | 786 | 1996 |
| Targeting transcription factors in cancer—from undruggable to reality JH Bushweller Nature Reviews Cancer 19 (11), 611-624, 2019 | 613 | 2019 |
| Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin X Han, JH Bushweller, DS Cafiso, LK Tamm Nature Structural & Molecular Biology 8 (8), 715, 2001 | 576 | 2001 |
| Structure of outer membrane protein A transmembrane domain by NMR spectroscopy A Arora, F Abildgaard, JH Bushweller, LK Tamm Nature Structural & Molecular Biology 8 (4), 334, 2001 | 541 | 2001 |
| Structural and functional characterization of the mutant Escherichia coli glutaredoxin (C14. fwdarw. S) and its mixed disulfide with glutathione JH Bushweller, F Aaslund, K Wuethrich, A Holmgren Biochemistry 31 (38), 9288-9293, 1992 | 322 | 1992 |
| Site-directed parallel spin-labeling and paramagnetic relaxation enhancement in structure determination of membrane proteins by solution NMR spectroscopy B Liang, JH Bushweller, LK Tamm Journal of the American Chemical Society 128 (13), 4389-4397, 2006 | 227 | 2006 |
| NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation Y Zhou, T Cierpicki, RHF Jimenez, SM Lukasik, JF Ellena, DS Cafiso, ... Molecular cell 31 (6), 896-908, 2008 | 213 | 2008 |
| Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia T Cierpicki, LE Risner, J Grembecka, SM Lukasik, R Popovic, ... Nature structural & molecular biology 17 (1), 62-68, 2010 | 205 | 2010 |
| Reduced dimensionality in triple-resonance NMR experiments T Szyperski, G Wider, JH Bushweller, K Wuethrich Journal of the American Chemical Society 115 (20), 9307-9308, 1993 | 205 | 1993 |
| The nuclear magnetic resonance solution structure of the mixed disulfide between Escherichia coli glutaredoxin (C14S) and glutathione JH Bushweller, M Billeter, A Holmgren, K Wüthrich Journal of molecular biology 235 (5), 1585-1597, 1994 | 184 | 1994 |
| The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity Y Liu, MD Cheney, JJ Gaudet, M Chruszcz, SM Lukasik, D Sugiyama, ... Cancer cell 9 (4), 249-260, 2006 | 180 | 2006 |
| NMR structure of oxidized Escherichia coli glutaredoxin: Comparison with reduced E. coli glutaredoxin and functionally related proteins TH Xia, JH Bushweller, P Sodano, M Billeter, O Björnberg, A Holmgren, ... Protein Science 1 (3), 310-321, 1992 | 162 | 1992 |
| The DCX-domain tandems of doublecortin and doublecortin-like kinase MH Kim, T Cierpicki, U Derewenda, D Krowarsch, Y Feng, Y Devedjiev, ... Nature Structural & Molecular Biology 10 (5), 324-333, 2003 | 157 | 2003 |
| Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity Y Liu, W Chen, J Gaudet, MD Cheney, L Roudaia, T Cierpicki, RC Klet, ... Cancer cell 11 (6), 483-497, 2007 | 143 | 2007 |
| Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFβ MJ Gorczynski, J Grembecka, Y Zhou, Y Kong, L Roudaia, MG Douvas, ... Chemistry & biology 14 (10), 1186-1197, 2007 | 141 | 2007 |
| Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant‐negative, or hypomorphic alleles CJ Matheny, ME Speck, PR Cushing, Y Zhou, T Corpora, M Regan, ... The EMBO journal 26 (4), 1163-1175, 2007 | 138 | 2007 |
| MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression FE Erfurth, R Popovic, J Grembecka, T Cierpicki, C Theisler, ZB Xia, ... Proceedings of the National Academy of Sciences 105 (21), 7517-7522, 2008 | 132 | 2008 |
| Charged gels as orienting media for measurement of residual dipolar couplings in soluble and integral membrane proteins T Cierpicki, JH Bushweller Journal of the American Chemical Society 126 (49), 16259-16266, 2004 | 124 | 2004 |
| A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice A Illendula, JA Pulikkan, H Zong, J Grembecka, L Xue, S Sen, Y Zhou, ... Science 347 (6223), 779-784, 2015 | 122 | 2015 |
