Christian W. Siebel
Christian W. Siebel
Principal Scientist, Genentech
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Cited by
Cited by
Therapeutic antibody targeting of individual Notch receptors
Y Wu, C Cain-Hom, L Choy, TJ Hagenbeek, GP de Leon, Y Chen, ...
Nature 464 (7291), 1052-1057, 2010
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells
KL VanDussen, AJ Carulli, TM Keeley, SR Patel, BJ Puthoff, ST Magness, ...
Development 139 (3), 488-497, 2012
Ras p21 as a potential mediator of insulin action in Xenopus oocytes
LJ Korn, CHW Siebel, F McCormick, RA Roth
Science 236 (4803), 840-843, 1987
Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation.
W Gilbert, CW Siebel, C Guthrie
Rna 7 (2), 302-313, 2001
Regulated splicing of the Drosophila P transposable element third intron in vitro: somatic repression
CW Siebel, DC Rio
Science 248 (4960), 1200-1208, 1990
The mechanism of somatic inhibition of Drosophila P-element pre-mRNA splicing: multiprotein complexes at an exon pseudo-5'splice site control U1 snRNP binding.
CW Siebel, LD Fresco, DC Rio
Genes & Development 6 (8), 1386-1401, 1992
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia
DJ Hodson, ML Janas, A Galloway, SE Bell, S Andrews, CM Li, R Pannell, ...
Nature immunology 11 (8), 717, 2010
Endothelial Notch1 activity facilitates metastasis
E Wieland, J Rodriguez-Vita, SS Liebler, C Mogler, I Moll, SE Herberich, ...
Cancer Cell 31 (3), 355-367, 2017
Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis
H Tian, B Biehs, C Chiu, CW Siebel, Y Wu, M Costa, FJ de Sauvage, ...
Cell reports 11 (1), 33-42, 2015
Conservation in budding yeast of a kinase specific for SR splicing factors
CW Siebel, L Feng, C Guthrie, XD Fu
Proceedings of the National Academy of Sciences 96 (10), 5440-5445, 1999
Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung
D Lafkas, A Shelton, C Chiu, G de Leon Boenig, Y Chen, SS Stawicki, ...
Nature 528 (7580), 127-131, 2015
Identification of putative noncoding polyadenylated transcripts in Drosophila melanogaster
JL Tupy, AM Bailey, G Dailey, M Evans-Holm, CW Siebel, S Misra, ...
Proceedings of the National Academy of Sciences 102 (15), 5495-5500, 2005
Soma-specific expression and cloning of PSI, a negative regulator of P element pre-mRNA splicing.
CW Siebel, A Admon, DC Rio
Genes & development 9 (3), 269-283, 1995
Regulation of tissue-specific P-element pre-mRNA splicing requires the RNA-binding protein PSI.
CW Siebel, R Kanaar, DC Rio
Genes & development 8 (14), 1713-1725, 1994
Blockade of individual Notch ligands and receptors controls graft-versus-host disease
IT Tran, AR Sandy, AJ Carulli, C Ebens, J Chung, GT Shan, V Radojcic, ...
The Journal of clinical investigation 123 (4), 1590-1604, 2013
Cloning and expression of the phospholipase C gene from Clostridium perfringens and Clostridium bifermentans.
JY Tso, C Siebel
Infection and Immunity 57 (2), 468-476, 1989
Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates
TL Cuellar, D Barnes, C Nelson, J Tanguay, SF Yu, X Wen, SJ Scales, ...
Nucleic acids research 43 (2), 1189-1203, 2015
The essential yeast RNA binding protein Npl3p is methylated
CW Siebel, C Guthrie
Proceedings of the National Academy of Sciences 93 (24), 13641-13646, 1996
Differential effects of targeting Notch receptors in a mouse model of liver cancer
EG Huntzicker, K Hötzel, L Choy, L Che, J Ross, G Pau, N Sharma, ...
Hepatology 61 (3), 942-952, 2015
The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development
K Niessen, G Zhang, JB Ridgway, H Chen, G Kolumam, CW Siebel, ...
Blood, The Journal of the American Society of Hematology 118 (7), 1989-1997, 2011
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