Michael Lobritz
Michael Lobritz
F. Hoffmann-La Roche, Ltd
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Antibiotics induce redox-related physiological alterations as part of their lethality
DJ Dwyer, PA Belenky, JH Yang, IC MacDonald, JD Martell, N Takahashi, ...
Proceedings of the National Academy of Sciences 111 (20), E2100-E2109, 2014
Antibiotic efficacy is linked to bacterial cellular respiration
MA Lobritz, P Belenky, CBM Porter, A Gutierrez, JH Yang, EG Schwarz, ...
Proceedings of the National Academy of Sciences 112 (27), 8173-8180, 2015
Microbial persistence and the road to drug resistance
NR Cohen, MA Lobritz, JJ Collins
Cell host & microbe 13 (6), 632-642, 2013
Bactericidal antibiotics induce toxic metabolic perturbations that lead to cellular damage
P Belenky, DY Jonathan, CBM Porter, NR Cohen, MA Lobritz, T Ferrante, ...
Cell reports 13 (5), 968-980, 2015
Bacterial metabolism and antibiotic efficacy
JM Stokes, AJ Lopatkin, MA Lobritz, JJ Collins
Cell metabolism 30 (2), 251-259, 2019
HLA-B57/B* 5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T …
T Miura, MA Brockman, A Schneidewind, M Lobritz, F Pereyra, A Rathod, ...
Journal of virology 83 (6), 2743-2755, 2009
Carbon sources tune antibiotic susceptibility in Pseudomonas aeruginosa via tricarboxylic acid cycle control
S Meylan, CBM Porter, JH Yang, P Belenky, A Gutierrez, MA Lobritz, ...
Cell chemical biology 24 (2), 195-206, 2017
Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C
SC Ball, A Abraha, KR Collins, AJ Marozsan, H Baird, ...
Journal of virology 77 (2), 1021-1038, 2003
Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response
RM Troyer, J McNevin, Y Liu, SC Zhang, RW Krizan, A Abraha, DM Tebit, ...
PLoS pathogens 5 (4), e1000365, 2009
A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs
KG Lassen, AM Hebbeler, D Bhattacharyya, MA Lobritz, WC Greene
PloS one 7 (1), e30176, 2012
Understanding and sensitizing density-dependent persistence to quinolone antibiotics
A Gutierrez, S Jain, P Bhargava, M Hamblin, MA Lobritz, JJ Collins
Molecular Cell 68 (6), 1147-1154. e3, 2017
Engineered phagemids for nonlytic, targeted antibacterial therapies
RJ Krom, P Bhargava, MA Lobritz, JJ Collins
Nano letters 15 (7), 4808-4813, 2015
Differences in the fitness of two diverse wild-type human immunodeficiency virus type 1 isolates are related to the efficiency of cell binding and entry
AJ Marozsan, DM Moore, MA Lobritz, E Fraundorf, A Abraha, JD Reeves, ...
Journal of virology 79 (11), 7121-7134, 2005
Elite suppressor–derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics
KG Lassen, MA Lobritz, JR Bailey, S Johnston, S Nguyen, B Lee, T Chou, ...
PLoS pathogens 5 (4), e1000377, 2009
A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains
SH Johnston, MA Lobritz, S Nguyen, K Lassen, S Delair, F Posta, ...
Journal of virology 83 (21), 11016-11026, 2009
HIV-1 entry, inhibitors, and resistance
MA Lobritz, AN Ratcliff, EJ Arts
Viruses 2 (5), 1069-1105, 2010
Recombination Proficiency Influences Frequency and Locus of Mutational Resistance to Linezolid in Enterococcus faecalis
M Lobritz, R Hutton-Thomas, S Marshall, LB Rice
Antimicrobial agents and chemotherapy 47 (10), 3318-3320, 2003
Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA
MS Lalonde, MA Lobritz, A Ratcliff, M Chamanian, Z Athanassiou, M Tyagi, ...
PLoS pathogens 7 (5), e1002038, 2011
Translocation and Surface Expression of Lipidated Serogroup B Capsular Polysaccharide in Neisseria meningitidis
YL Tzeng, AK Datta, CA Strole, MA Lobritz, RW Carlson, DS Stephens
Infection and immunity 73 (3), 1491-1505, 2005
Natural variation in the V3 crown of human immunodeficiency virus type 1 affects replicative fitness and entry inhibitor sensitivity
MA Lobritz, AJ Marozsan, RM Troyer, EJ Arts
Journal of virology 81 (15), 8258-8269, 2007
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