Hui Guo
Hui Guo
Reader in Biostatistics, University of Manchester
Verified email at
Cited by
Cited by
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
S Onengut-Gumuscu, WM Chen, O Burren, NJ Cooper, AR Quinlan, ...
Nature genetics 47 (4), 381-386, 2015
Widespread seasonal gene expression reveals annual differences in human immunity and physiology
XC Dopico, M Evangelou, RC Ferreira, H Guo, ML Pekalski, DJ Smyth, ...
Nature communications 6 (1), 7000, 2015
A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes
RC Ferreira, H Guo, RMR Coulson, DJ Smyth, ML Pekalski, OS Burren, ...
Diabetes 63 (7), 2538-2550, 2014
Seven newly identified loci for autoimmune thyroid disease
JD Cooper, MJ Simmonds, NM Walker, O Burren, OJ Brand, H Guo, ...
Human molecular genetics 21 (23), 5202-5208, 2012
Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls
MD Fortune, H Guo, O Burren, E Schofield, NM Walker, M Ban, SJ Sawcer, ...
Nature genetics 47 (7), 839-846, 2015
Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases
H Guo, MD Fortune, OS Burren, E Schofield, JA Todd, C Wallace
Human molecular genetics 24 (12), 3305-3313, 2015
A method for gene‐based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations
M Evangelou, DJ Smyth, MD Fortune, OS Burren, NM Walker, H Guo, ...
Genetic epidemiology 38 (8), 661-670, 2014
Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes
WS Thompson, ML Pekalski, HZ Simons, DJ Smyth, X Castro-Dopico, ...
Clinical & Experimental Immunology 177 (3), 571-585, 2014
Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors
ML Pekalski, RC Ferreira, RMR Coulson, AJ Cutler, H Guo, DJ Smyth, ...
The Journal of Immunology 190 (6), 2554-2566, 2013
Sensitivity to pain expectations: A Bayesian model of individual differences
R Hoskin, C Berzuini, D Acosta-Kane, W El-Deredy, H Guo, D Talmi
Cognition 182, 127-139, 2019
Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping
C Wallace, AJ Cutler, N Pontikos, ML Pekalski, OS Burren, JD Cooper, ...
PLoS genetics 11 (6), e1005272, 2015
Molecular insights into genome-wide association studies of chronic kidney disease-defining traits
X Xu, JM Eales, A Akbarov, H Guo, L Becker, D Talavera, F Ashraf, ...
Nature communications 9 (1), 4800, 2018
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
JM Eales, X Jiang, X Xu, S Saluja, A Akbarov, E Cano-Gamez, ...
Nature genetics 53 (5), 630-637, 2021
A Bayesian approach to Mendelian randomization with multiple pleiotropic variants
C Berzuini, H Guo, S Burgess, L Bernardinelli
Biostatistics 21 (1), 86-101, 2020
Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics
J Rowland, A Akbarov, J Eales, X Xu, JP Dormer, H Guo, M Denniff, ...
Kidney international 95 (3), 624-635, 2019
Obesity and cancer treatment outcomes: interpreting the complex evidence
CGV Slawinski, J Barriuso, H Guo, AG Renehan
Clinical Oncology 32 (9), 591-608, 2020
Type 1 diabetes genetics C, Todd JA, Wallace C, Concannon P, rich SS. fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants …
S Onengut-Gumuscu, WM Chen, O Burren, NJ Cooper, AR Quinlan, ...
Nat Genet 47, 381-386, 2015
Sufficient covariates and linear propensity analysis
H Guo, P Dawid
Proceedings of the Thirteenth International Conference on Artificial …, 2010
Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes
NJ Cooper, CJ Shtir, DJ Smyth, H Guo, AD Swafford, M Zanda, ME Hurles, ...
Human molecular genetics 24 (6), 1774-1790, 2015
VSEAMS: a pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes
OS Burren, H Guo, C Wallace
Bioinformatics 30 (23), 3342-3348, 2014
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