High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy C Krieg, M Nowicka, S Guglietta, S Schindler, FJ Hartmann, LM Weber, ... Nature medicine 24 (2), 144-153, 2018 | 700 | 2018 |
Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’ AM Levin, DL Bates, AM Ring, C Krieg, JT Lin, L Su, I Moraga, ME Raeber, ... Nature 484 (7395), 529-533, 2012 | 568 | 2012 |
CyTOF workflow: differential discovery in high-throughput high-dimensional cytometry datasets M Nowicka, C Krieg, HL Crowell, LM Weber, FJ Hartmann, S Guglietta, ... F1000Research 6, 2017 | 473 | 2017 |
Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells C Krieg, S Létourneau, G Pantaleo, O Boyman Proceedings of the National Academy of Sciences 107 (26), 11906-11911, 2010 | 424 | 2010 |
ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial JM Wrangle, V Velcheti, MR Patel, E Garrett-Mayer, EG Hill, JG Ravenel, ... The Lancet Oncology 19 (5), 694-704, 2018 | 386 | 2018 |
IL-2–and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets S Létourneau, C Krieg, G Pantaleo, O Boyman Journal of Allergy and Clinical Immunology 123 (4), 758-762, 2009 | 363 | 2009 |
Homeostatic proliferation and survival of naive and memory T cells O Boyman, S Létourneau, C Krieg, J Sprent European journal of immunology 39 (8), 2088-2094, 2009 | 341 | 2009 |
IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor α subunit CD25 S Létourneau, EMM van Leeuwen, C Krieg, C Martin, G Pantaleo, ... Proceedings of the National Academy of Sciences 107 (5), 2171-2176, 2010 | 259 | 2010 |
The end of gating? An introduction to automated analysis of high dimensional cytometry data F Mair, FJ Hartmann, D Mrdjen, V Tosevski, C Krieg, B Becher European journal of immunology 46 (1), 34-43, 2016 | 256 | 2016 |
Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis S Guglietta, A Chiavelli, E Zagato, C Krieg, S Gandini, PS Ravenda, ... Nature communications 7 (1), 11037, 2016 | 249 | 2016 |
Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection O Chijioke, A Müller, R Feederle, MHM Barros, C Krieg, V Emmel, ... Cell reports 5 (6), 1489-1498, 2013 | 248 | 2013 |
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates L Cassetta, ES Baekkevold, S Brandau, A Bujko, MA Cassatella, A Dorhoi, ... Cancer Immunology, Immunotherapy 68, 687-697, 2019 | 215 | 2019 |
GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis E Galli, FJ Hartmann, B Schreiner, F Ingelfinger, E Arvaniti, M Diebold, ... Nature medicine 25 (8), 1290-1300, 2019 | 177 | 2019 |
B and T lymphocyte attenuator regulates CD8+ T cell–intrinsic homeostasis and memory cell generation C Krieg, O Boyman, YX Fu, J Kaye Nature immunology 8 (2), 162-171, 2007 | 161 | 2007 |
Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells C Krieg, P Han, R Stone, OD Goularte, J Kaye The Journal of Immunology 175 (10), 6420-6427, 2005 | 134 | 2005 |
Type 2 interleukin-4 receptor signaling in neutrophils antagonizes their expansion and migration during infection and inflammation J Woytschak, N Keller, C Krieg, D Impellizzieri, RW Thompson, TA Wynn, ... Immunity 45 (1), 172-184, 2016 | 128 | 2016 |
Homeostatic maintenance of T cells and natural killer cells O Boyman, C Krieg, D Homann, J Sprent Cellular and molecular life Sciences 69, 1597-1608, 2012 | 117 | 2012 |
High-dimensional single-cell analysis reveals the immune signature of narcolepsy FJ Hartmann, R Bernard-Valnet, C Quériault, D Mrdjen, LM Weber, E Galli, ... Journal of experimental medicine 213 (12), 2621-2633, 2016 | 115 | 2016 |
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β A Metelli, BX Wu, B Riesenberg, S Guglietta, JD Huck, C Mills, A Li, ... Science translational medicine 12 (525), eaay4860, 2020 | 93 | 2020 |
Circulating neutrophil subsets in advanced lung cancer patients exhibit unique immune signature and relate to prognosis ME Shaul, O Eyal, S Guglietta, P Aloni, A Zlotnik, E Forkosh, L Levy, ... The FASEB Journal 34 (3), 4204-4218, 2020 | 88 | 2020 |