| Tetrahydropterin-dependent amino acid hydroxylases PF Fitzpatrick Annual review of biochemistry 68 (1), 355-381, 1999 | 699 | 1999 |
| Crystal structure of tyrosine hydroxylase at 2.3 Å and its implications for inherited neurodegenerative diseases KE Goodwill, C Sabatier, C Marks, R Raag, PF Fitzpatrick, RC Stevens Nature structural biology 4 (7), 578-585, 1997 | 371 | 1997 |
| Mechanism of aromatic amino acid hydroxylation PF Fitzpatrick Biochemistry 42 (48), 14083-14091, 2003 | 349 | 2003 |
| Structures and mechanism of the monoamine oxidase family H Gaweska, PF Fitzpatrick Walter de Gruyter 2 (5), 365-377, 2011 | 273 | 2011 |
| Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat I Becher, T Werner, C Doce, EA Zaal, I Tögel, CA Khan, A Rueger, ... Nature chemical biology 12 (11), 908-910, 2016 | 246 | 2016 |
| Oxidation of amines by flavoproteins PF Fitzpatrick Archives of biochemistry and biophysics 493 (1), 13-25, 2010 | 240 | 2010 |
| Direct spectroscopic evidence for a high-spin Fe (IV) intermediate in tyrosine hydroxylase BE Eser, EW Barr, PA Frantom, L Saleh, JM Bollinger Jr, C Krebs, ... Journal of the American Chemical Society 129 (37), 11334-11335, 2007 | 232 | 2007 |
| Site-directed mutagenesis of serine 40 of rat tyrosine hydroxylase. Effects of dopamine and cAMP-dependent phosphorylation on enzyme activity. SC Daubner, C Lauriano, JW Haycock, PF Fitzpatrick Journal of Biological Chemistry 267 (18), 12639-12646, 1992 | 218 | 1992 |
| Human isoferritins in normal and disease states. JW Drysdale, TG Adelman, P Arosio, D Casareale, P Fitzpatrick, ... | 187 | 1977 |
| Characterization of the active site iron in tyrosine hydroxylase: Redox states of the iron AJ Ramsey, PJ Hillas, PF Fitzpatrick Journal of Biological Chemistry 271 (40), 24395-24400, 1996 | 155 | 1996 |
| Steady-state kinetic mechanism of rat tyrosine hydroxylase PF Fitzpatrick Biochemistry 30 (15), 3658-3662, 1991 | 143 | 1991 |
| The aromatic amino acid hydroxylases PF Fitzpatrick Advances in enzymology and related areas of molecular biology 74, 235-294, 2000 | 138 | 2000 |
| Domain movements upon activation of phenylalanine hydroxylase characterized by crystallography and chromatography-coupled small-angle X-ray scattering SP Meisburger, AB Taylor, CA Khan, S Zhang, PF Fitzpatrick, N Ando Journal of the American Chemical Society 138 (20), 6506-6516, 2016 | 132 | 2016 |
| Substrate dehydrogenation by flavoproteins PF Fitzpatrick Accounts of Chemical Research 34 (4), 299-307, 2001 | 128 | 2001 |
| Effects of phosphorylation of serine 40 of tyrosine hydroxylase on binding of catecholamines: evidence for a novel regulatory mechanism AJ Ramsey, PF Fitzpatrick Biochemistry 37 (25), 8980-8986, 1998 | 122 | 1998 |
| Mechanisms of tryptophan and tyrosine hydroxylase KM Roberts, PF Fitzpatrick IUBMB life 65 (4), 350-357, 2013 | 114 | 2013 |
| Evidence for a high-spin Fe (IV) species in the catalytic cycle of a bacterial phenylalanine hydroxylase AJ Panay, M Lee, C Krebs, JM Bollinger Jr, PF Fitzpatrick Biochemistry 50 (11), 1928-1933, 2011 | 114 | 2011 |
| A mechanism for hydroxylation by tyrosine hydroxylase based on partitioning of substituted phenylalanines PJ Hillas, PF Fitzpatrick Biochemistry 35 (22), 6969-6975, 1996 | 111 | 1996 |
| Expression and characterization of the catalytic core of tryptophan hydroxylase GR Moran, SC Daubner, PF Fitzpatrick Journal of Biological Chemistry 273 (20), 12259-12266, 1998 | 101 | 1998 |
| Carbanion versus hydride transfer mechanisms in flavoprotein-catalyzed dehydrogenations PF Fitzpatrick Bioorganic chemistry 32 (3), 125-139, 2004 | 100 | 2004 |
