| Somatic coding mutations in human induced pluripotent stem cells A Gore, Z Li, HL Fung, JE Young, S Agarwal, J Antosiewicz-Bourget, ... Nature 471 (7336), 63-67, 2011 | 1450 | 2011 |
| Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome GH Liu, BZ Barkho, S Ruiz, D Diep, J Qu, SL Yang, AD Panopoulos, ... Nature 472 (7342), 221-225, 2011 | 628 | 2011 |
| The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming AD Panopoulos, O Yanes, S Ruiz, YS Kida, D Diep, R Tautenhahn, ... Cell research 22 (1), 168-177, 2012 | 584 | 2012 |
| Progressive degeneration of human neural stem cells caused by pathogenic LRRK2 GH Liu, J Qu, K Suzuki, E Nivet, M Li, N Montserrat, F Yi, X Xu, S Ruiz, ... Nature 491 (7425), 603-607, 2012 | 400 | 2012 |
| A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity S Ruiz, AD Panopoulos, A Herrerías, KD Bissig, M Lutz, WT Berggren, ... Current Biology 21 (1), 45-52, 2011 | 351 | 2011 |
| Functional roles of Akt signaling in mouse skin tumorigenesis C Segrelles, S Ruiz, P Perez, C Murga, M Santos, IV Budunova, ... Oncogene 21 (1), 53-64, 2002 | 207 | 2002 |
| Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells S Ruiz, D Diep, A Gore, AD Panopoulos, N Montserrat, N Plongthongkum, ... Proceedings of the National Academy of Sciences 109 (40), 16196-16201, 2012 | 196 | 2012 |
| A genome-wide CRISPR screen identifies CDC25A as a determinant of sensitivity to ATR inhibitors S Ruiz, C Mayor-Ruiz, V Lafarga, M Murga, M Vega-Sendino, S Ortega, ... Molecular cell 62 (2), 307-313, 2016 | 194 | 2016 |
| Conversion of human fibroblasts to angioblast-like progenitor cells L Kurian, I Sancho-Martinez, E Nivet, A Aguirre, K Moon, C Pendaries, ... Nature methods 10 (1), 77-83, 2013 | 191 | 2013 |
| Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis S Ruiz, M Santos, C Segrelles, H Leis, JL Jorcano, A Berns, JM Paramio, ... Oxford University Press for The Company of Biologists Limited 131 (11), 2737 …, 2004 | 169 | 2004 |
| Inhibition of protein kinase B (PKB) and PKCζ mediates keratin K10-induced cell cycle arrest JM Paramio, C Segrelles, S Ruiz, JL Jorcano Molecular and cellular biology 21 (21), 7449-7459, 2001 | 160 | 2001 |
| Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs GH Liu, K Suzuki, M Li, J Qu, N Montserrat, C Tarantino, Y Gu, F Yi, X Xu, ... Nature communications 5 (1), 4330, 2014 | 133 | 2014 |
| Molecular determinants of Akt-induced keratinocyte transformation C Segrelles, M Moral, MF Lara, S Ruiz, M Santos, H Leis, ... Oncogene 25 (8), 1174-1185, 2006 | 123 | 2006 |
| Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded, placebo-controlled … PG Kremsner, RAA Guerrero, E Arana-Arri, GJA Martinez, M Bonten, ... The Lancet Infectious Diseases 22 (3), 329-340, 2022 | 117 | 2022 |
| Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells S Ruiz, AJ Lopez-Contreras, M Gabut, RM Marion, P Gutierrez-Martinez, ... Nature communications 6 (1), 8036, 2015 | 105 | 2015 |
| Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis C Segrelles, J Lu, B Hammann, M Santos, M Moral, JL Cascallana, ... Cancer research 67 (22), 10879-10888, 2007 | 101 | 2007 |
| Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors AB Martínez-Cruz, M Santos, MF Lara, C Segrelles, S Ruiz, M Moral, ... Cancer research 68 (3), 683-692, 2008 | 88 | 2008 |
| Expression, localization, and activity of glycogen synthase kinase 3β during mouse skin tumorigenesis H Leis, C Segrelles, S Ruiz, M Santos, JM Paramio Molecular Carcinogenesis: Published in cooperation with the University of …, 2002 | 87 | 2002 |
| High-efficient generation of induced pluripotent stem cells from human astrocytes S Ruiz, K Brennand, AD Panopoulos, A Herrerías, FH Gage, ... PloS one 5 (12), e15526, 2010 | 86 | 2010 |
| A p53-dependent response limits the viability of mammalian haploid cells T Olbrich, C Mayor-Ruiz, M Vega-Sendino, C Gomez, S Ortega, S Ruiz, ... Proceedings of the National Academy of Sciences 114 (35), 9367-9372, 2017 | 76 | 2017 |
