| Direct pharmacological targeting of a mitochondrial ion channel selectively kills tumor cells in vivo L Leanza, M Romio, KA Becker, M Azzolini, L Trentin, A Manago, ... Cancer cell 31 (4), 516-531. e10, 2017 | 149 | 2017 |
| Impaired mitochondrial ATP production downregulates Wnt signaling via ER stress induction R Costa, R Peruzzo, M Bachmann, G Dalla Monta, M Vicario, G Santinon, ... Cell reports 28 (8), 1949-1960. e6, 2019 | 69 | 2019 |
| Impact of intracellular ion channels on cancer development and progression R Peruzzo, L Biasutto, I Szabò, L Leanza European Biophysics Journal 45, 685-707, 2016 | 54 | 2016 |
| Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma A Zaccagnino, A Managò, L Leanza, A Gontarewitz, B Linder, M Azzolini, ... Oncotarget 8 (24), 38276, 2017 | 48 | 2017 |
| Contribution of mitochondrial ion channels to chemo-resistance in cancer cells R Peruzzo, I Szabo Cancers 11 (6), 761, 2019 | 37 | 2019 |
| Mitochondrial potassium channels in cell death V Checchetto, M Azzolini, R Peruzzo, P Capitanio, L Leanza Biochemical and biophysical research communications 500 (1), 51-58, 2018 | 34 | 2018 |
| Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL MA Pagano, E Tibaldi, P Molino, F Frezzato, V Trimarco, M Facco, ... Leukemia 33 (5), 1148-1160, 2019 | 33 | 2019 |
| Mitochondrial metabolism, contact sites and cellular calcium signaling: implications for tumorigenesis R Peruzzo, R Costa, M Bachmann, L Leanza, I Szabò Cancers 12 (9), 2574, 2020 | 22 | 2020 |
| The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease C Goul, R Peruzzo, R Zoncu Nature Reviews Molecular Cell Biology 24 (12), 857-875, 2023 | 21 | 2023 |
| Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1. 3 channel inhibitors by chemical dissection of a novel member of the family R Peruzzo, A Mattarei, M Azzolini, KA Becker-Flegler, M Romio, G Rigoni, ... Redox biology 37, 101705, 2020 | 21 | 2020 |
| Targeting mitochondrial ion channels to fight cancer M Bachmann, R Costa, R Peruzzo, E Prosdocimi, V Checchetto, L Leanza International journal of molecular sciences 19 (7), 2060, 2018 | 21 | 2018 |
| Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation RM Jansen, R Peruzzo, SA Fromm, AL Yokom, R Zoncu, JH Hurley Science advances 8 (37), eadd2926, 2022 | 19 | 2022 |
| Pterostilbene improves cognitive performance in aged rats: an in vivo study M La Spina, G Sansevero, L Biasutto, M Zoratti, R Peruzzo, N Berardi, ... Cell Physiol Biochem 52 (2), 232-239, 2019 | 19 | 2019 |
| Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction R Peruzzo, S Corrà, R Costa, M Brischigliaro, T Varanita, L Biasutto, ... Nature Communications 12 (1), 2103, 2021 | 18 | 2021 |
| Regulation of proliferation by a mitochondrial potassium channel in pancreatic ductal adenocarcinoma cells R Peruzzo, A Mattarei, M Romio, C Paradisi, M Zoratti, I Szabò, L Leanza Frontiers in Oncology 7, 239, 2017 | 18 | 2017 |
| A novel mitochondrial Kv1. 3–caveolin axis controls cell survival and apoptosis J Capera, M Pérez-Verdaguer, R Peruzzo, M Navarro-Pérez, ... Elife 10, e69099, 2021 | 11 | 2021 |
| The displacement of frataxin from the mitochondrial cristae correlates with abnormal respiratory supercomplexes formation and bioenergetic defects in cells of Friedreich ataxia … D Doni, G Rigoni, E Palumbo, E Baschiera, R Peruzzo, E De Rosa, ... The FASEB Journal 35 (3), e21362, 2021 | 11 | 2021 |
| Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11. 1 activation in breast cancer cells and PDOs V Senyuk, N Eskandari, Y Jiang, R Garcia-Varela, R Sundstrom, L Leanza, ... Redox Biology 45, 102030, 2021 | 8 | 2021 |
| Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3. 1 triggers cell death and reduces tumor growth and metastasis in vivo M Bachmann, A Rossa, T Varanita, B Fioretti, L Biasutto, S Milenkovic, ... Cell Death & Disease 13 (12), 1055, 2022 | 7 | 2022 |
| G× E interactions as a basis for toxicological uncertainty I Suciu, D Pamies, R Peruzzo, PH Wirtz, L Smirnova, G Pallocca, C Hauck, ... Archives of Toxicology 97 (7), 2035-2049, 2023 | 4 | 2023 |
