フォロー
Tsuyoshi Hirota
Tsuyoshi Hirota
確認したメール アドレス: itbm.nagoya-u.ac.jp
タイトル
引用先
引用先
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis
EE Zhang, Y Liu, R Dentin, PY Pongsawakul, AC Liu, T Hirota, ...
Nature medicine 16 (10), 1152-1156, 2010
5182010
A genome-wide RNAi screen for modifiers of the circadian clock in human cells
EE Zhang, AC Liu, T Hirota, LJ Miraglia, G Welch, PY Pongsawakul, X Liu, ...
Cell 139 (1), 199-210, 2009
4412009
Identification of small molecule activators of cryptochrome
T Hirota, JW Lee, PC St. John, M Sawa, K Iwaisako, T Noguchi, ...
Science 337 (6098), 1094-1097, 2012
4112012
Glucose Down-regulates Per1 and Per2mRNA Levels and Induces Circadian Gene Expression in Cultured Rat-1 Fibroblasts* 210
T Hirota, T Okano, K Kokame, H Shirotani-Ikejima, T Miyata, Y Fukada
Journal of Biological Chemistry 277 (46), 44244-44251, 2002
3532002
Resetting mechanism of central and peripheral circadian clocks in mammals
T Hirota, Y Fukada
Zoological science 21 (4), 359-368, 2004
3002004
A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β
T Hirota, WG Lewis, AC Liu, JW Lee, PG Schultz, SA Kay
Proceedings of the National Academy of Sciences 105 (52), 20746-20751, 2008
2882008
Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3β
Y Harada, M Sakai, N Kurabayashi, T Hirota, Y Fukada
Journal of Biological Chemistry 280 (36), 31714-31721, 2005
2282005
High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase
T Hirota, JW Lee, WG Lewis, EE Zhang, G Breton, X Liu, M Garcia, ...
PLoS biology 8 (12), e1000559, 2010
2242010
DYRK1A and glycogen synthase kinase 3β, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping
N Kurabayashi, T Hirota, M Sakai, K Sanada, Y Fukada
Molecular and cellular biology 30 (7), 1757-1768, 2010
1552010
Activation of TGF-β/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts
N Kon, T Hirota, T Kawamoto, Y Kato, T Tsubota, Y Fukada
Nature cell biology 10 (12), 1463-1469, 2008
1362008
Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies
M Hatori, C Gronfier, RN Van Gelder, PS Bernstein, J Carreras, S Panda, ...
NPJ aging and mechanisms of disease 3 (1), 1-3, 2017
1272017
Circadian amplitude regulation via FBXW7-targeted REV-ERBα degradation
X Zhao, T Hirota, X Han, H Cho, LW Chong, K Lamia, S Liu, AR Atkins, ...
Cell 165 (7), 1644-1657, 2016
1172016
Chicken pineal clock genes: implication of BMAL2 as a bidirectional regulator in circadian clock oscillation
T Okano, K Yamamoto, K Okano, T Hirota, T Kasahara, M Sasaki, ...
Genes to Cells 6 (9), 825-836, 2001
1082001
Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth
T Oshima, Y Niwa, K Kuwata, A Srivastava, T Hyoda, Y Tsuchiya, ...
Science advances 5 (1), eaau9060, 2019
682019
Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1, and heat shock factor pathways
M Hatori, T Hirota, M Iitsuka, N Kurabayashi, S Haraguchi, K Kokame, ...
Proceedings of the National Academy of Sciences 108 (12), 4864-4869, 2011
662011
Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock
TN Uehara, Y Mizutani, K Kuwata, T Hirota, A Sato, J Mizoi, S Takao, ...
Proceedings of the National Academy of Sciences 116 (23), 11528-11536, 2019
612019
C H Activation Generates Period‐Shortening Molecules That Target Cryptochrome in the Mammalian Circadian Clock
T Oshima, I Yamanaka, A Kumar, J Yamaguchi, T Nishiwaki‐Ohkawa, ...
Angewandte Chemie International Edition 54 (24), 7193-7197, 2015
612015
A small molecule modulates circadian rhythms through phosphorylation of the period protein
JW Lee, T Hirota, EC Peters, M Garcia, R Gonzalez, CY Cho, X Wu, ...
Angewandte Chemie 123 (45), 10796-10799, 2011
602011
Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock
PC St. John, T Hirota, SA Kay, FJ Doyle III
Proceedings of the National Academy of Sciences 111 (5), 2040-2045, 2014
582014
Real-time in vivo monitoring of circadian E-box enhancer activity: a robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the …
M Weger, BD Weger, N Diotel, S Rastegar, T Hirota, SA Kay, U Strähle, ...
Developmental Biology 380 (2), 259-273, 2013
582013
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