| 5-Aryl-1,2-dihydrochromeno[3,4-f]quinolines: A Novel Class of Nonsteroidal Human Progesterone Receptor Agonists L Zhi, CM Tegley, EA Kallel, KB Marschke, DE Mais, MM Gottardis, ... Journal of medicinal chemistry 41 (3), 291-302, 1998 | 150 | 1998 |
| Substituent effects on rates and stereoselectivities of conrotatory electrocyclic reactions of cyclobutenes. A theoretical study S Niwayama, EA Kallel, DC Spellmeyer, C Sheu, KN Houk The Journal of Organic Chemistry 61 (8), 2813-2825, 1996 | 145 | 1996 |
| Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery. CT 1) Sean Ekins , Jair Lage de Siqueira-Neto , Laura-Isobel McCall ... PLoS Negl Trop Dis 9 (6), 2015 | 82 | 2015 |
| Theoretical Predictions of Substituent Effects on the Thermal Electrocyclic Ring Openings of Cyclobutenones S Niwayama, EA Kallel, C Sheu, KN Houk The Journal of Organic Chemistry 61 (7), 2517-2522, 1996 | 69 | 1996 |
| Theoretical predictions of torquoselectivity in pentadienyl cation electrocyclizations EA Kallel, KN Houk The Journal of Organic Chemistry 54 (26), 6006-6008, 1989 | 62 | 1989 |
| Correlation between chemotype-dependent binding conformations of HSP90α/β and isoform selectivity-Implications for the structure-based design of HSP90α/β selective inhibitors … SD Ernst JT, Liu M, Zuccola H, Neubert T, Beaumont K, Turnbull A, Kallel A ... Bioorg Med Chem Lett 24 (1), 204-8, 2014 | 61 | 2014 |
| Androgen receptor modulator compounds and methods L Zhi, RI Higuchi, CA Van Oeveren, TLS Lau US Patent 8,519,158, 2013 | 54 | 2013 |
| Altering the allowed/forbidden gap in cyclobutene electrocyclic reactions: Experimental and theoretical evaluations of the effect of planarity constraints PS Lee, S Sakai, P Hörstermann, WR Roth, EA Kallel, KN Houk Journal of the American Chemical Society 125 (19), 5839-5848, 2003 | 53 | 2003 |
| Thrombopoietin activity modulating compounds and methods L Zhi, EA Kallel, DP Phillips US Patent 7,662,804, 2010 | 51 | 2010 |
| Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels SSH Ruah, EA Kallel, MT Miller, V Arumugam, J McCartney, C Anderson, ... US Patent 8,916,565, 2014 | 49* | 2014 |
| Electrocyclic ring openings of dialkylcyclobutenes: anomalies explained EA Kallel, Y Wang, DC Spellmeyer, KN Houk Journal of the American Chemical Society 112 (19), 6759-6763, 1990 | 49 | 1990 |
| Novel selective androgen receptor modulators: SAR studies on 6-bisalkylamino-2-quinolinones. ZL van Oeveren A, Motamedi M, Martinborough E, Zhao S, Shen Y, West S, Chang ... Bioorg Med Chem Lett. 17 (6), 1527-31, 2007 | 48 | 2007 |
| Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226 F Wang, X Liu, H Li, K Liang, JN Miner, M Hong, EA Kallel, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 48 | 2006 |
| Synthesis and characterization of nonsteroidal glucocorticoid receptor modulators for multiple myeloma AR Hudson, SL Roach, RI Higuchi, DP Phillips, RP Bissonnette, ... Journal of medicinal chemistry 50 (19), 4699-4709, 2007 | 45 | 2007 |
| Torquoselectivity induced by lone-pair conjugation in the electrocyclic reactions of 1-azapolyenes MJ Walker, BN Hietbrink, BE Thomas, K Nakamura, EA Kallel, KN Houk The Journal of Organic Chemistry 66 (20), 6669-6672, 2001 | 36 | 2001 |
| Chroman-spirocyclic piperidine amides as modulators of ion channels SS Hadida-Ruah, MT Miller, EA Kallel, BR Bear, V Arumugam, ... US Patent 10,385,070, 2019 | 28 | 2019 |
| Morpholine-spirocyclic piperidine amides as modulators of ion channels SS Hadida-Ruah, HM Binch, MP Deninno, LTD Fanning, BA Frieman, ... US Patent 8,828,996, 2014 | 28 | 2014 |
| Thrombopoietin activity modulating compounds and methods JH Chen, EA Kallel, T Lau, MH Mcneill, TA Miller, BN Nguyen, ... US Patent 7,314,887, 2008 | 20 | 2008 |
| Potent, nonsteroidal selective androgen receptor modulators (SARMs) based on 8H-[1, 4] oxazino [2, 3-f] quinolin-8-ones RI Higuchi, AW Thompson, JH Chen, TR Caferro, ML Cummings, ... Bioorganic & medicinal chemistry letters 17 (19), 5442-5446, 2007 | 19 | 2007 |
| Synthesis and structure-activity relationships of potent retinoid X receptor ligands LJ Farmer, S Jeong, EA Kallel, SSC Koch, GE Croston, KS Flatten, ... Bioorganic & Medicinal Chemistry Letters 7 (18), 2393-2398, 1997 | 18 | 1997 |
Jeffrey N. MinerViscient Biosciences and OrganovoVerified email at viscientbio.com
