Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors AA Manzoor, LH Lindner, CD Landon, JY Park, AJ Simnick, MR Dreher, ... Cancer research 72 (21), 5566-5575, 2012 | 507 | 2012 |
Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin RM Schiffelers, GA Koning, TLM ten Hagen, MHAM Fens, AJ Schraa, ... Journal of Controlled Release 91 (1-2), 115-122, 2003 | 450 | 2003 |
Endosomal escape of polymeric gene delivery complexes is not always enhanced by polymers buffering at low pH AM Funhoff, CF van Nostrum, GA Koning, ... Biomacromolecules 5 (1), 32-39, 2004 | 379 | 2004 |
MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle WJM Mulder, GJ Strijkers, JW Habets, EJW Bleeker, DWJ Van Der Schaft, ... The FASEB journal 19 (14), 2008-2010, 2005 | 352 | 2005 |
Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors GA Koning, AMM Eggermont, LH Lindner, TLM ten Hagen Pharmaceutical research 27, 1750-1754, 2010 | 323 | 2010 |
A liposomal system for contrast-enhanced magnetic resonance imaging of molecular targets WJM Mulder, GJ Strijkers, AW Griffioen, L van Bloois, G Molema, G Storm, ... Bioconjugate chemistry 15 (4), 799-806, 2004 | 311 | 2004 |
Cellular uptake of cationic polymer-DNA complexes via caveolae plays a pivotal role in gene transfection in COS-7 cells M Van Der Aa, US Huth, SY Häfele, R Schubert, RS Oosting, ... Pharmaceutical research 24, 1590-1598, 2007 | 297 | 2007 |
Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins E Mastrobattista, GA Koning, L van Bloois, ACS Filipe, W Jiskoot, G Storm Journal of Biological Chemistry 277 (30), 27135-27143, 2002 | 291 | 2002 |
Immunoliposomes for the targeted delivery of antitumor drugs E Mastrobattista, GA Koning, G Storm Advanced drug delivery reviews 40 (1-2), 103-127, 1999 | 273 | 1999 |
Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy L Li, TLM ten Hagen, M Hossann, R Süss, GC van Rhoon, ... Journal of Controlled Release 168 (2), 142-150, 2013 | 257 | 2013 |
Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia L Li, TLM ten Hagen, D Schipper, TM Wijnberg, GC van Rhoon, ... Journal of Controlled Release 143 (2), 274-279, 2010 | 254 | 2010 |
Publications from 2010 RCN van den Bergh, MLE Essink-Bot, MJ Roobol-Bouts, FH Schröder, ... The Journal of Urology 183 (5), 1786-1791, 2010 | 250* | 2010 |
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate–containing RGD peptide liposomes inhibits experimental arthritis GA Koning, RM Schiffelers, MHM Wauben, RJ Kok, E Mastrobattista, ... Arthritis & Rheumatism 54 (4), 1198-1208, 2006 | 226 | 2006 |
Improved intratumoral nanoparticle extravasation and penetration by mild hyperthermia L Li, TLM ten Hagen, M Bolkestein, A Gasselhuber, J Yatvin, ... Journal of Controlled Release 167 (2), 130-137, 2013 | 216 | 2013 |
The nuclear pore complex: the gateway to successful nonviral gene delivery MAEM van der Aa, E Mastrobattista, RS Oosting, WE Hennink, GA Koning, ... Pharmaceutical research 23, 447-459, 2006 | 205 | 2006 |
Intact Doxil is taken up intracellularly and released doxorubicin sequesters in the lysosome: Evaluated by in vitro in vivo live cell imaging ALB Seynhaeve, BM Dicheva, S Hoving, GA Koning, TLM ten Hagen Journal of Controlled Release 172 (1), 330-340, 2013 | 184 | 2013 |
A novel 111In-labeled anti–prostate-specific membrane antigen nanobody for targeted SPECT/CT imaging of prostate cancer KLS Chatalic, J Veldhoven-Zweistra, M Bolkestein, S Hoeben, GA Koning, ... Journal of Nuclear Medicine 56 (7), 1094-1099, 2015 | 146 | 2015 |
Cationic thermosensitive liposomes: a novel dual targeted heat-triggered drug delivery approach for endothelial and tumor cells BM Dicheva, TLM Hagen, L Li, D Schipper, ALB Seynhaeve, GC Rhoon, ... Nano letters 13 (6), 2324-2331, 2013 | 145 | 2013 |
Peptide-targeted PEG-liposomes in anti-angiogenic therapy A Janssen, RM Schiffelers, TLM Ten Hagen, GA Koning, AJ Schraa, ... International journal of pharmaceutics 254 (1), 55-58, 2003 | 145 | 2003 |
Water-soluble biodegradable cationic polyphosphazenes for gene delivery J Luten, JH Van Steenis, R Van Someren, J Kemmink, ... Journal of controlled release 89 (3), 483-497, 2003 | 142 | 2003 |