| Translation from the 5′ untranslated region shapes the integrated stress response SR Starck, JC Tsai, K Chen, M Shodiya, L Wang, K Yahiro, ... Science 351 (6272), aad3867, 2016 | 356 | 2016 |
| Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori A Fujikawa, D Shirasaka, S Yamamoto, H Ota, K Yahiro, M Fukada, ... Nature genetics 33 (3), 375-381, 2003 | 334 | 2003 |
| Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines V Supajatura, H Ushio, A Wada, K Yahiro, K Okumura, H Ogawa, ... The Journal of Immunology 168 (6), 2603-2607, 2002 | 224 | 2002 |
| Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase β K Yahiro, T Niidome, M Kimura, T Hatakeyama, H Aoyagi, H Kurazono, ... Journal of Biological Chemistry 274 (51), 36693-36699, 1999 | 220 | 1999 |
| Protein-tyrosine phosphatase α, RPTPα, is a Helicobacter pylori VacA receptor K Yahiro, A Wada, M Nakayama, T Kimura, K Ogushi, T Niidome, ... Journal of Biological Chemistry 278 (21), 19183-19189, 2003 | 163 | 2003 |
| Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signaling pathway M Nakayama, J Hisatsune, E Yamasaki, H Isomoto, H Kurazono, ... Journal of biological chemistry 284 (3), 1612-1619, 2009 | 156 | 2009 |
| Vacuolating cytotoxin purified fromHelicobacter pyloricauses mitochondrial damage in human gastric cells M Kimura, S Goto, A Wada, K Yahiro, T Niidome, T Hatakeyama, H Aoyagi, ... Microbial pathogenesis 26 (1), 45-52, 1999 | 138 | 1999 |
| Low-density lipoprotein receptor-related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA K Yahiro, M Satoh, M Nakano, J Hisatsune, H Isomoto, J Sap, H Suzuki, ... Journal of Biological Chemistry 287 (37), 31104-31115, 2012 | 136 | 2012 |
| Helicobacter pylori VacA activates the p38/activating transcription factor 2-mediated signal pathway in AZ-521 cells M Nakayama, M Kimura, A Wada, K Yahiro, K Ogushi, T Niidome, ... Journal of Biological Chemistry 279 (8), 7024-7028, 2004 | 119 | 2004 |
| Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response … J Hisatsune, M Nakayama, H Isomoto, H Kurazono, N Mukaida, ... The Journal of Immunology 180 (7), 5017-5027, 2008 | 112 | 2008 |
| Morphologic Differentiation of HL-60 Cells Is Associated with Appearance of RPTPβ and Induction of Helicobacter pyloriVacA Sensitivity PI Padilla, A Wada, K Yahiro, M Kimura, T Niidome, H Aoyagi, A Kumatori, ... Journal of Biological Chemistry 275 (20), 15200-15206, 2000 | 105 | 2000 |
| Helicobacter pyloriVacuolating Cytotoxin Binds to the 140-kDa Protein in Human Gastric Cancer Cell Lines, AZ-521 and AGS K Yahiro, T Niidome, T Hatakeyama, H Aoyagi, H Kurazono, PI Padilla, ... Biochemical and Biophysical Research Communications 238 (2), 629-632, 1997 | 105 | 1997 |
| Differential activities of plant polyphenols on the binding and internalization of cholera toxin in vero cells N Morinaga, Y Iwamaru, K Yahiro, M Tagashira, J Moss, M Noda Journal of Biological Chemistry 280 (24), 23303-23309, 2005 | 94 | 2005 |
| Inhibitory effects of various plant polyphenols on the toxicity of Staphylococcal α-toxin O Choi, K Yahiro, N Morinaga, M Miyazaki, M Noda Microbial pathogenesis 42 (5-6), 215-224, 2007 | 79 | 2007 |
| Clustering of Helicobacter pylori VacA in Lipid Rafts, Mediated by Its Receptor, Receptor-Like Protein Tyrosine Phosphatase β, Is Required for Intoxication in AZ … M Nakayama, J Hisatsune, E Yamasaki, Y Nishi, A Wada, H Kurazono, ... Infection and immunity 74 (12), 6571-6580, 2006 | 72 | 2006 |
| Inhibitory Effects of Polyphenols on Gastric Injury by Helicobacter pylori VacA Toxin K Yahiro, D Shirasaka, M Tagashira, A Wada, N Morinaga, F Kuroda, ... Helicobacter 10 (3), 231-239, 2005 | 66 | 2005 |
| Subtilase cytotoxin, produced by Shiga‐toxigenic Escherichia coli, transiently inhibits protein synthesis of Vero cells via degradation of BiP and induces cell cycle … N Morinaga, K Yahiro, G Matsuura, J Moss, M Noda Cellular microbiology 10 (4), 921-929, 2008 | 63 | 2008 |
| Impairment of glutathione metabolism in human gastric epithelial cells treated with vacuolating cytotoxin fromHelicobacter pylori M Kimura, S Goto, Y Ihara, A Wada, K Yahiro, T Niidome, H Aoyagi, ... Microbial pathogenesis 31 (1), 29-36, 2001 | 62 | 2001 |
| Two Distinct Cytotoxic Activities of Subtilase Cytotoxin Produced by Shiga-Toxigenic Escherichia coli N Morinaga, K Yahiro, G Matsuura, M Watanabe, F Nomura, J Moss, ... Infection and immunity 75 (1), 488-496, 2007 | 61 | 2007 |
| Helicobacter pylori VacA induces apoptosis by accumulation of connexin 43 in autophagic vesicles via a Rac1/ERK-dependent pathway K Yahiro, Y Akazawa, M Nakano, H Suzuki, J Hisatune, H Isomoto, J Sap, ... Cell death discovery 1 (1), 1-15, 2015 | 57 | 2015 |
