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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 M Ko, Y Huang, AM Jankowska, UJ Pape, M Tahiliani, HS Bandukwala, ... Nature 468 (7325), 839-843, 2010 | 1524 | 2010 |
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells WA Pastor, UJ Pape, Y Huang, HR Henderson, R Lister, M Ko, ... Nature 473 (7347), 394-397, 2011 | 978 | 2011 |
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing Y Huang, WA Pastor, Y Shen, M Tahiliani, DR Liu, A Rao PloS one 5 (1), e8888, 2010 | 887 | 2010 |
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells KP Koh, A Yabuuchi, S Rao, Y Huang, K Cunniff, J Nardone, A Laiho, ... Cell stem cell 8 (2), 200-213, 2011 | 880 | 2011 |
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A AM Jankowska, H Makishima, RV Tiu, H Szpurka, Y Huang, F Traina, ... Blood, The Journal of the American Society of Hematology 118 (14), 3932-3941, 2011 | 365 | 2011 |
Control of Foxp3 stability through modulation of TET activity X Yue, S Trifari, T Äijö, A Tsagaratou, WA Pastor, JA Zepeda-Martínez, ... Journal of Experimental Medicine 213 (3), 377-397, 2016 | 332 | 2016 |
Large conserved domains of low DNA methylation maintained by Dnmt3a M Jeong, D Sun, M Luo, Y Huang, GA Challen, B Rodriguez, X Zhang, ... Nature genetics 46 (1), 17-23, 2014 | 332 | 2014 |
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells Y Huang, L Chavez, X Chang, X Wang, WA Pastor, J Kang, ... Proceedings of the National Academy of Sciences 111 (4), 1361-1366, 2014 | 308 | 2014 |
Connections between TET proteins and aberrant DNA modification in cancer Y Huang, A Rao Trends in Genetics 30 (10), 464-474, 2014 | 293 | 2014 |
STIM1 gates the store-operated calcium channel ORAI1 in vitro Y Zhou, P Meraner, HT Kwon, D Machnes, M Oh-Hora, J Zimmer, ... Nature structural & molecular biology 17 (1), 112-116, 2010 | 288 | 2010 |
DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells X Zhang, J Su, M Jeong, M Ko, Y Huang, HJ Park, A Guzman, Y Lei, ... Nature genetics 48 (9), 1014-1023, 2016 | 268 | 2016 |
Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation YZ Lian He, Yuanwei Zhang, Guolin Ma, Peng Tan, Zhanjun Li, Shengbing Zang ... eLife 4 (e10024), 2015 | 246 | 2015 |
Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca2+ influx YZ Ji Jing, Lian He, Aomin Sun, Ariel Quintana, Yuehe Ding, Guolin Ma, Peng ... Nature cell biology 17 (10), 1339-1347, 2015 | 240 | 2015 |
Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells JJ Vincent, Y Huang, PY Chen, S Feng, JH Calvopiña, K Nee, SA Lee, ... Cell stem cell 12 (4), 470-478, 2013 | 215 | 2013 |
Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation A Tsagaratou, T Äijö, CWJ Lio, X Yue, Y Huang, SE Jacobsen, ... Proceedings of the National Academy of Sciences 111 (32), E3306-E3315, 2014 | 176 | 2014 |
The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine JP Etchegaray, L Chavez, Y Huang, KN Ross, J Choi, B Martinez-Pastor, ... Nature cell biology 17 (5), 545-557, 2015 | 172 | 2015 |
DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells T Gu, X Lin, SM Cullen, M Luo, M Jeong, M Estecio, J Shen, S Hardikar, ... Genome biology 19, 1-15, 2018 | 163 | 2018 |
Multiple Ca2+-Binding Sites in the Extracellular Domain of the Ca2+-Sensing Receptor Corresponding to Cooperative Ca2+ Response Y Huang, Y Zhou, A Castiblanco, W Yang, EM Brown, JJ Yang Biochemistry 48 (2), 388-398, 2009 | 149 | 2009 |
Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety NT Nguyen, K Huang, H Zeng, J Jing, R Wang, S Fang, J Chen, X Liu, ... Nature nanotechnology 16 (12), 1424-1434, 2021 | 137 | 2021 |