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Ian F Harrison
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Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model
IF Harrison, O Ismail, A Machhada, N Colgan, Y Ohene, P Nahavandi, ...
Brain 143 (8), 2576-2593, 2020
2962020
Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease?
IF Harrison, DT Dexter
Pharmacology & therapeutics 140 (1), 34-52, 2013
2462013
Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease
N Colgan, B Siow, JM O'Callaghan, IF Harrison, JA Wells, HE Holmes, ...
Neuroimage 125, 739-744, 2016
2222016
Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI
IF Harrison, B Siow, AB Akilo, PG Evans, O Ismail, Y Ohene, P Nahavandi, ...
Elife 7, e34028, 2018
1482018
Non-invasive MRI of brain clearance pathways using multiple echo time arterial spin labelling: an aquaporin-4 study
Y Ohene, IF Harrison, P Nahavandi, O Ismail, EV Bird, OP Ottersen, ...
Neuroimage 188, 515-523, 2019
1202019
Pathological histone acetylation in Parkinson’s disease: Neuroprotection and inhibition of microglial activation through SIRT 2 inhibition
IF Harrison, AD Smith, DT Dexter
Neuroscience letters 666, 48-57, 2018
1092018
Non-invasive MRI of blood–cerebrospinal fluid barrier function
PG Evans, M Sokolska, A Alves, IF Harrison, Y Ohene, P Nahavandi, ...
Nature communications 11 (1), 2081, 2020
802020
The Discovery of a Highly Selective 5,6,7,8‐Tetrahydrobenzo[4,5]thieno[2,3‐d]pyrimidin‐4(3H)‐one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson …
P Di Fruscia, E Zacharioudakis, C Liu, S Moniot, S Laohasinnarong, ...
ChemMedChem 10 (1), 69-82, 2015
802015
Prazosin, an α1-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease
L Katsouri, MP Vizcaychipi, S McArthur, I Harrison, M Suárez-Calvet, ...
Neurobiology of aging 34 (4), 1105-1115, 2013
762013
Impaired brain glymphatic flow in experimental hepatic encephalopathy
A Hadjihambi, IF Harrison, M Costas-Rodríguez, F Vanhaecke, N Arias, ...
Journal of hepatology 70 (1), 40-49, 2019
702019
An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson’s disease
IS Pienaar, IF Harrison, JL Elson, A Bury, P Woll, AK Simon, DT Dexter
Brain Structure and Function 220, 479-500, 2015
612015
Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease
J O'callaghan, H Holmes, N Powell, JA Wells, O Ismail, IF Harrison, ...
Neuroimage 159, 334-345, 2017
592017
Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of P arkinson's is associated with histone acetylation and up‐regulation of …
IF Harrison, WR Crum, AC Vernon, DT Dexter
British journal of pharmacology 172 (16), 4200-4215, 2015
542015
People with Parkinson’s disease: what symptoms do they most want to improve and how does this change with disease duration?
RJ Port, M Rumsby, G Brown, IF Harrison, A Amjad, CJ Bale
Journal of Parkinson's disease 11 (2), 715-724, 2021
482021
The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease
IF Harrison, NM Powell, DT Dexter
Journal of neurochemistry 148 (1), 136-156, 2019
482019
Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy
HE Holmes, NM Powell, D Ma, O Ismail, IF Harrison, JA Wells, N Colgan, ...
Frontiers in neuroinformatics 11, 20, 2017
452017
Imaging the accumulation and suppression of tau pathology using multiparametric MRI
HE Holmes, N Colgan, O Ismail, D Ma, NM Powell, JM O'Callaghan, ...
Neurobiology of aging 39, 184-194, 2016
452016
Increased blood–brain barrier permeability to water in the aging brain detected using noninvasive multi‐TE ASL MRI
Y Ohene, IF Harrison, PG Evans, DL Thomas, MF Lythgoe, JA Wells
Magnetic resonance in medicine 85 (1), 326-333, 2021
282021
L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils
A Migdalska‐Richards, M Wegrzynowicz, IF Harrison, G Verona, V Bellotti, ...
PLoS One 15 (8), e0238075, 2020
282020
Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system
DM Lopes, SK Llewellyn, IF Harrison
Translational Neurodegeneration 11 (1), 19, 2022
252022
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Articles 1–20