Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation JA Knauf, X Ma, EP Smith, L Zhang, N Mitsutake, XH Liao, S Refetoff, ... Cancer research 65 (10), 4238-4245, 2005 | 525 | 2005 |
Frequent Somatic TERT Promoter Mutations in Thyroid Cancer: Higher Prevalence in Advanced Forms of the Disease I Landa, I Ganly, TA Chan, N Mitsutake, M Matsuse, T Ibrahimpasic, ... The Journal of Clinical Endocrinology & Metabolism 98 (9), E1562-E1566, 2013 | 479 | 2013 |
Characterization of side population in thyroid cancer cell lines: cancer stem-like cells are enriched partly but not exclusively N Mitsutake, A Iwao, K Nagai, H Namba, A Ohtsuru, V Saenko, ... Endocrinology 148 (4), 1797-1803, 2007 | 328 | 2007 |
Oncogenic role of miR‐17‐92 cluster in anaplastic thyroid cancer cells S Takakura, N Mitsutake, M Nakashima, H Namba, VA Saenko, ... Cancer science 99 (6), 1147-1154, 2008 | 293 | 2008 |
Conditional BRAFV600E Expression Induces DNA Synthesis, Apoptosis, Dedifferentiation, and Chromosomal Instability in Thyroid PCCL3 Cells N Mitsutake, JA Knauf, S Mitsutake, C Mesa Jr, L Zhang, JA Fagin Cancer research 65 (6), 2465-2473, 2005 | 280 | 2005 |
MiR-195, miR-455-3p and miR-10a∗ are implicated in acquired temozolomide resistance in glioblastoma multiforme cells K Ujifuku, N Mitsutake, S Takakura, M Matsuse, V Saenko, K Suzuki, ... Cancer letters 296 (2), 241-248, 2010 | 274 | 2010 |
Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia K Kashiyama, Y Nakazawa, DT Pilz, C Guo, M Shimada, K Sasaki, ... The American Journal of Human Genetics 92 (5), 807-819, 2013 | 256 | 2013 |
Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair Y Nakazawa, K Sasaki, N Mitsutake, M Matsuse, M Shimada, T Nardo, ... Nature genetics 44 (5), 586-592, 2012 | 216 | 2012 |
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl M Takahashi, VA Saenko, TI Rogounovitch, T Kawaguchi, VM Drozd, ... Human molecular genetics 19 (12), 2516-2523, 2010 | 210 | 2010 |
Ubiquitination of DNA damage-stalled RNAPII promotes transcription-coupled repair Y Nakazawa, Y Hara, Y Oka, O Komine, D van den Heuvel, C Guo, ... Cell 180 (6), 1228-1244. e24, 2020 | 183 | 2020 |
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells K Matsushima, H Isomoto, N Yamaguchi, N Inoue, H Machida, ... Journal of translational medicine 9, 1-12, 2011 | 178 | 2011 |
miR-196a downregulation increases the expression of type I and III collagens in keloid fibroblasts K Kashiyama, N Mitsutake, M Matsuse, T Ogi, VA Saenko, K Ujifuku, ... Journal of Investigative Dermatology 132 (6), 1597-1604, 2012 | 167 | 2012 |
Conditional activation of RET/PTC3 and BRAFV600E in thyroid cells is associated with gene expression profiles that predict a preferential role of BRAF in extracellular matrix … C Mesa Jr, M Mirza, N Mitsutake, M Sartor, M Medvedovic, C Tomlinson, ... Cancer research 66 (13), 6521-6529, 2006 | 163 | 2006 |
Endogenous expression of HrasG12V induces developmental defects and neoplasms with copy number imbalances of the oncogene X Chen, N Mitsutake, K LaPerle, N Akeno, P Zanzonico, VA Longo, ... Proceedings of the National Academy of Sciences 106 (19), 7979-7984, 2009 | 153 | 2009 |
BRAFV600E Promotes Invasiveness of Thyroid Cancer Cells through Nuclear Factor κB Activation I Palona, H Namba, N Mitsutake, D Starenki, A Podtcheko, I Sedliarou, ... Endocrinology 147 (12), 5699-5707, 2006 | 150 | 2006 |
Polymorphisms of DNA damage response genes in radiation-related and sporadic papillary thyroid carcinoma NM Akulevich, VA Saenko, TI Rogounovitch, VM Drozd, EF Lushnikov, ... Endocrine-related cancer 16 (2), 491-503, 2009 | 141 | 2009 |
BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary … N Mitsutake, M Miyagishi, S Mitsutake, N Akeno, C Mesa, JA Knauf, ... Endocrinology 147 (2), 1014-1019, 2006 | 137 | 2006 |
Identification of the first ATRIP–deficient patient and novel mutations in ATR define a clinical spectrum for ATR–ATRIP Seckel syndrome T Ogi, S Walker, T Stiff, E Hobson, S Limsirichaikul, G Carpenter, ... PLoS genetics 8 (11), e1002945, 2012 | 122 | 2012 |
Aberrant localization of β-catenin correlates with overexpression of its target gene in human papillary thyroid cancer K Ishigaki, H Namba, M Nakashima, T Nakayama, N Mitsutake, T Hayashi, ... The Journal of Clinical Endocrinology & Metabolism 87 (7), 3433-3440, 2002 | 117 | 2002 |
The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population M Matsuse, M Takahashi, N Mitsutake, E Nishihara, M Hirokawa, ... Journal of medical genetics 48 (9), 645-648, 2011 | 110 | 2011 |