| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1899* | 2020 |
| IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression A Sadik, LFS Patterson, S Öztürk, SR Mohapatra, V Panitz, PF Secker, ... Cell 182 (5), 1252-1270. e34, 2020 | 369 | 2020 |
| The landscape of viral associations in human cancers M Zapatka*, I Borozan*, DS Brewer*, M Iskar*, A Grundhoff, M Alawi, ... Nature Genetics, 1-12, 2020 | 349 | 2020 |
| Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines A Ori, N Banterle, M Iskar, A Andrés-Pons, C Escher, HK Bui, L Sparks, ... Molecular Systems Biology 9 (1), 2013 | 340 | 2013 |
| Tumor-derived exosomes modulate PD-L1 expression in monocytes F Haderk, R Schulz, M Iskar, LL Cid, T Worst, KV Willmund, A Schulz, ... Science immunology 2 (13), eaah5509, 2017 | 302 | 2017 |
| Prediction of drug combinations by integrating molecular and pharmacological data XM Zhao, M Iskar, G Zeller, M Kuhn, V Van Noort, P Bork PLoS computational biology 7 (12), e1002323, 2011 | 213 | 2011 |
| Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats A Ori, BH Toyama, MS Harris, T Bock, M Iskar, P Bork, NT Ingolia, ... Cell systems 1 (3), 224-237, 2015 | 192 | 2015 |
| Drug-induced regulation of target expression M Iskar, M Campillos, M Kuhn, LJ Jensen, V van Noort, P Bork PLoS computational biology 6 (9), e1000925, 2010 | 175 | 2010 |
| Luminal signalling links cell communication to tissue architecture during organogenesis S Durdu, M Iskar, C Revenu, N Schieber, A Kunze, P Bork, Y Schwab, ... Nature 515 (7525), 120-124, 2014 | 158 | 2014 |
| Characterization of drug‐induced transcriptional modules: towards drug repositioning and functional understanding M Iskar, G Zeller, P Blattmann, M Campillos, M Kuhn, KH Kaminska, ... Molecular systems biology 9 (1), 662, 2013 | 140 | 2013 |
| Drug discovery in the age of systems biology: the rise of computational approaches for data integration M Iskar*, G Zeller*, XM Zhao, V van Noort, P Bork Current opinion in biotechnology 23 (4), 609-616, 2012 | 134 | 2012 |
| Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling V van Noort*, S Schölch*, M Iskar*, G Zeller, K Ostertag, C Schweitzer, ... Cancer research 74 (20), 5690-5699, 2014 | 108 | 2014 |
| Network neighbors of drug targets contribute to drug side-effect similarity L Brouwers, M Iskar, G Zeller, V Van Noort, P Bork PloS one 6 (7), e22187, 2011 | 108 | 2011 |
| Spatiotemporal variation of mammalian protein complex stoichiometries A Ori*, M Iskar*, K Buczak, P Kastritis, L Parca, A Andrés-Pons, S Singer, ... Genome biology 17 (1), 1, 2016 | 103 | 2016 |
| Identification and analyses of extra-cranial and cranial rhabdoid tumor molecular subgroups reveal tumors with cytotoxic T cell infiltration HJE Chun, PD Johann, K Milne, M Zapatka, A Buellesbach, N Ishaque, ... Cell reports 29 (8), 2338-2354. e7, 2019 | 96 | 2019 |
| DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data C Pacini, F Iorio, E Gonçalves, M Iskar, T Klabunde, P Bork, ... Bioinformatics 29 (1), 132-134, 2013 | 83 | 2013 |
| Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity BS Hanna, L Llao-Cid, M Iskar, PM Roessner, LC Klett, JKL Wong, Y Paul, ... Immunity 54 (12), 2825-2841. e10, 2021 | 76 | 2021 |
| Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations E Pfaff, C Aichmüller, M Sill, D Stichel, M Snuderl, MA Karajannis, ... Acta neuropathologica 139, 243-257, 2020 | 67 | 2020 |
| Quantitative proteome landscape of the NCI-60 cancer cell lines T Guo, A Luna, VN Rajapakse, CC Koh, Z Wu, W Liu, Y Sun, H Gao, ... Iscience 21, 664-680, 2019 | 57* | 2019 |
| Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks JP Mallm*, M Iskar*, N Ishaque*, LC Klett, SJ Kugler, JM Muino, VB Teif, ... Molecular systems biology 15 (5), 2019 | 53 | 2019 |
Peer BorkDirector of EMBL HeidelbergVerified email at embl.de
