cDNA cloning and tissue-specific expression of a novel basic helix–loop–helix/PAS protein (BMAL1) and identification of alternatively spliced variants with alternative … M Ikeda, M Nomura Biochemical and biophysical research communications 233 (1), 258-264, 1997 | 283 | 1997 |
Circadian Oscillation of BMAL1, a Partner of a Mammalian Clock Gene Clock, in Rat Suprachiasmatic Nucleus S Honma, M Ikeda, H Abe, Y Tanahashi, M Namihira, K Honma, ... Biochemical and biophysical research communications 250 (1), 83-87, 1998 | 237 | 1998 |
Clock genes outside the suprachiasmatic nucleus involved in manifestation of locomotor activity rhythm in rats S Masubuchi, S Honma, H Abe, K Ishizaki, M Namihira, M Ikeda, ... European Journal of Neuroscience 12 (12), 4206-4214, 2000 | 215 | 2000 |
Interactivating feedback loops within the mammalian clock: BMAL1 is negatively autoregulated and upregulated by CRY1, CRY2, and PER2 W Yu, M Nomura, M Ikeda Biochemical and biophysical research communications 290 (3), 933-941, 2002 | 201 | 2002 |
Mutation screening of the human Clock gene in circadian rhythm sleep disorders T Iwase, N Kajimura, M Uchiyama, T Ebisawa, K Yoshimura, Y Kamei, ... Psychiatry research 109 (2), 121-128, 2002 | 183 | 2002 |
CLOCK/BMAL1 is involved in lipid metabolism via transactivation of the peroxisome proliferator-activated receptor (PPAR) response element I Inoue, Y Shinoda, M Ikeda, K Hayashi, K Kanazawa, M Nomura, ... Journal of atherosclerosis and thrombosis 12 (3), 169-174, 2005 | 167 | 2005 |
Multicolor luciferase assay system: one-step monitoring of multiple gene expressions with a single substrate Y Nakajima, T Kimura, K Sugata, T Enomoto, A Asakawa, H Kubota, ... Biotechniques 38 (6), 891-894, 2005 | 113 | 2005 |
Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth T Oshima, Y Niwa, K Kuwata, A Srivastava, T Hyoda, Y Tsuchiya, ... Science advances 5 (1), eaau9060, 2019 | 110 | 2019 |
Daily variation and light responsiveness of mammalian clock gene, Clock and BMAL1, transcripts in the pineal body and different areas of brain in rats M Namihira, S Honma, H Abe, Y Tanahashi, M Ikeda, K Honma Neuroscience letters 267 (1), 69-72, 1999 | 108 | 1999 |
Bidirectional role of orphan nuclear receptor RORα in clock gene transcriptions demonstrated by a novel reporter assay system Y Nakajima, M Ikeda, T Kimura, S Honma, Y Ohmiya, K Honma FEBS letters 565 (1-3), 122-126, 2004 | 104 | 2004 |
Circadian rhythm and light responsiveness of BMAL1 expression, a partner of mammalian clock gene Clock, in the suprachiasmatic nucleus of rats H Abe, S Honma, M Namihira, Y Tanahashi, M Ikeda, K Honma Neuroscience letters 258 (2), 93-96, 1998 | 84 | 1998 |
Modulation of gamma-aminobutyric acid-stimulated chloride influx by bicycloorthocarboxylates, bicyclophosphorus esters, polychlorocycloalkanes and other cage convulsants. T Obata, HI Yamamura, E Malatynska, M Ikeda, H Laird, CJ Palmer, ... Journal of Pharmacology and Experimental Therapeutics 244 (3), 802-806, 1988 | 77 | 1988 |
Clock gene expressions in the suprachiasmatic nucleus and other areas of the brain during rhythm splitting in CS mice H Abe, S Honma, M Namihira, S Masubuchi, M Ikeda, S Ebihara, ... Molecular brain research 87 (1), 92-99, 2001 | 70 | 2001 |
New reporter system for Per1 and Bmal1 expressions revealed self‐sustained circadian rhythms in peripheral tissues S Nishide, S Honma, Y Nakajima, M Ikeda, K Baba, Y Ohmiya, K Honma Genes to Cells 11 (10), 1173-1182, 2006 | 68 | 2006 |
Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina M Namihira, S Honma, H Abe, S Masubuchi, M Ikeda, K Honma Neuroreport 12 (3), 471-475, 2001 | 65 | 2001 |
cDNA Cloning of a Novel bHLH-PAS Transcription Factor Superfamily Gene, BMAL2: Its mRNA Expression, Subcellular Distribution, and Chromosomal Localization M Ikeda, W Yu, M Hirai, T Ebisawa, S Honma, K Yoshimura, KI Honma, ... Biochemical and biophysical research communications 275 (2), 493-502, 2000 | 65 | 2000 |
Alleic variants of human melatonin 1a receptor: function and prevalence in subjects with circadian rhythm sleep disorders T Ebisawa, N Kajimura, M Uchiyama, M Katoh, M Sekimoto, T Watanabe, ... Biochemical and biophysical research communications 262 (3), 832-837, 1999 | 62 | 1999 |
In vitro circadian period is associated with circadian/sleep preference A Hida, S Kitamura, Y Ohsawa, M Enomoto, Y Katayose, Y Motomura, ... Scientific reports 3 (1), 2074, 2013 | 56 | 2013 |
Dual-color luciferase mouse directly demonstrates coupled expression of two clock genes T Noguchi, T Michihata, W Nakamura, T Takumi, R Shimizu, M Yamamoto, ... Biochemistry 49 (37), 8053-8061, 2010 | 56 | 2010 |
Phase-dependent induction by light of rat Clock gene expression in the suprachiasmatic nucleus H Abe, S Honma, M Namihira, Y Tanahashi, M Ikeda, W Yu, K Honma Molecular brain research 66 (1), 104-110, 1999 | 54 | 1999 |