| Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells F Osakada, H Ikeda, M Mandai, T Wataya, K Watanabe, N Yoshimura, ... Nature biotechnology 26 (2), 215-224, 2008 | 740 | 2008 |
| α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A β-amyloid-induced neurotoxicity T Kihara, S Shimohama, H Sawada, K Honda, T Nakamizo, H Shibasaki, ... Journal of Biological Chemistry 276 (17), 13541-13546, 2001 | 508 | 2001 |
| Nicotinic receptor stimulation protects neurons against β‐amyloid toxicity T Kihara, S Shimohama, H Sawada, J Kimura, T Kume, H Kochiyama, ... Annals of Neurology: Official Journal of the American Neurological …, 1997 | 424 | 1997 |
| Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia? A Nishiyori, M Minami, Y Ohtani, S Takami, J Yamamoto, N Kawaguchi, ... FEBS letters 429 (2), 167-172, 1998 | 394 | 1998 |
| Wnt signaling promotes regeneration in the retina of adult mammals F Osakada, S Ooto, T Akagi, M Mandai, A Akaike, M Takahashi Journal of Neuroscience 27 (15), 4210-4219, 2007 | 382 | 2007 |
| Microglia‐derived interleukin‐6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells M Nakanishi, T Niidome, S Matsuda, A Akaike, T Kihara, H Sugimoto European Journal of Neuroscience 25 (3), 649-658, 2007 | 368 | 2007 |
| Estradiol protects mesencephalic dopaminergic neurons from oxidative stress‐induced neuronal death H Sawada, M Ibi, T Kihara, M Urushitani, A Akaike, S Shimohama Journal of neuroscience research 54 (5), 707-719, 1998 | 324 | 1998 |
| Protective effects of 1α, 25-(OH) 2D3 against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture M Ibi, H Sawada, M Nakanishi, T Kume, H Katsuki, S Kaneko, ... Neuropharmacology 40 (6), 761-771, 2001 | 305 | 2001 |
| Phosphatidylinositol 3‐kinase mediates neuroprotection by estrogen in cultured cortical neurons K Honda, H Sawada, T Kihara, M Urushitani, T Nakamizo, A Akaike, ... Journal of neuroscience research 60 (3), 321-327, 2000 | 302 | 2000 |
| Nicotine-induced protection of cultured cortical neurons againstN-methyl-D-aspartate receptor-mediated glutamate cytotoxicity A Akaike, Y Tamura, T Yokota, S Shimohama, J Kimura Brain research 644 (2), 181-187, 1994 | 297 | 1994 |
| Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons Y Takada, A Yonezawa, T Kume, H Katsuki, S Kaneko, H Sugimoto, ... Journal of Pharmacology and Experimental Therapeutics 306 (2), 772-777, 2003 | 262 | 2003 |
| Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features Y Shimmyo, T Kihara, A Akaike, T Niidome, H Sugimoto Biochimica et Biophysica Acta (BBA)-General Subjects 1780 (5), 819-825, 2008 | 261 | 2008 |
| A critical role of TRPM2 in neuronal cell death by hydrogen peroxide S Kaneko, S Kawakami, Y Hara, M Wakamori, E Itoh, T Minami, Y Takada, ... Journal of pharmacological sciences 101 (1), 66-76, 2006 | 251 | 2006 |
| Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via α7-neuronal receptors and neuronal CNS receptors S Kaneko, T Maeda, T Kume, H Kochiyama, A Akaike, S Shimohama, ... Brain research 765 (1), 135-140, 1997 | 251 | 1997 |
| Stimulation of α4β2 nicotinic acetylcholine receptors inhibits β-amyloid toxicity T Kihara, S Shimohama, M Urushitani, H Sawada, J Kimura, T Kume, ... Brain research 792 (2), 331-334, 1998 | 249 | 1998 |
| Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults M Okawara, H Katsuki, E Kurimoto, H Shibata, T Kume, A Akaike Biochemical pharmacology 73 (4), 550-560, 2007 | 246 | 2007 |
| Analgesia induced by microinjection of morphine into, and electrical stimulation of, the nucleus reticularis paragigantocellularis of rat medulla oblongata A Akaike, T Shibata, M Satoh, H Takagi Neuropharmacology 17 (9), 775-778, 1978 | 234 | 1978 |
| Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase … Y Takada-Takatori, T Kume, M Sugimoto, H Katsuki, H Sugimoto, ... Neuropharmacology 51 (3), 474-486, 2006 | 232 | 2006 |
| Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of α4 and α7 receptors in neuroprotection A Akaike, Y Takada-Takatori, T Kume, Y Izumi Journal of Molecular Neuroscience 40, 211-216, 2010 | 223 | 2010 |
| Mechanisms of antiapoptotic effects of estrogens in nigral dopaminergic neurons H Sawada, M Ibi, T Kihara, M Urushitani, K Honda, M Nakanishi, A Akaike, ... The FASEB Journal 14 (9), 1202-1214, 2000 | 213 | 2000 |
Kume ToshiakiKyoto UniversityVerified email at pharm.kyoto-u.ac.jp
