フォロー
Finny S. Varghese
Finny S. Varghese
Department of Medical Microbiology, Radboud University Medical Center
確認したメール アドレス: radboudumc.nl
タイトル
引用先
引用先
Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses
FS Varghese, P Kaukinen, S Gläsker, M Bespalov, L Hanski, ...
Antiviral research 126, 117-124, 2016
2272016
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell Stem Cell 29 (2), 217-231. e8, 2022
1812022
The antiviral alkaloid berberine reduces chikungunya virus-induced mitogen-activated protein kinase signaling
FS Varghese, B Thaa, SN Amrun, D Simarmata, K Rausalu, TA Nyman, ...
Journal of virology 90 (21), 9743-9757, 2016
1472016
Differential phosphatidylinositol-3-kinase-Akt-mTOR activation by Semliki Forest and chikungunya viruses is dependent on nsP3 and connected to replication complex internalization
B Thaa, R Biasiotto, K Eng, M Neuvonen, B Götte, L Rheinemann, ...
Journal of virology 89 (22), 11420-11437, 2015
1142015
Obatoclax inhibits alphavirus membrane fusion by neutralizing the acidic environment of endocytic compartments
FS Varghese, K Rausalu, M Hakanen, S Saul, BM Kümmerer, P Susi, ...
Antimicrobial agents and chemotherapy 61 (3), 10.1128/aac. 02227-16, 2017
712017
Design and validation of novel chikungunya virus protease inhibitors
PK Das, L Puusepp, FS Varghese, A Utt, T Ahola, DG Kananovich, ...
Antimicrobial agents and chemotherapy 60 (12), 7382-7395, 2016
692016
Berberine and obatoclax inhibit SARS-Cov-2 replication in primary human nasal epithelial cells in vitro
FS Varghese, E van Woudenbergh, GJ Overheul, MJ Eleveld, L Kurver, ...
Viruses 13 (2), 282, 2021
642021
Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease’s active site cysteine residue
K Rausalu, A Utt, T Quirin, FS Varghese, E Žusinaite, PK Das, T Ahola, ...
Scientific reports 6 (1), 37124, 2016
632016
Natural variation in resistance to virus infection in dipteran insects
WH Palmer, FS Varghese, RP Van Rij
Viruses 10 (3), 118, 2018
622018
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine …
H Achdout, A Aimon, E Bar-David, GM Morris
BioRxiv, 2020
542020
Population genomics in the arboviral vector Aedes aegypti reveals the genomic architecture and evolution of endogenous viral elements
CM Crava, FS Varghese, E Pischedda, R Halbach, U Palatini, ...
Molecular ecology 30 (7), 1594-1611, 2021
402021
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
372020
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
312023
Natural variation in resistance to virus infection in dipteran insects. Viruses 10: 118
WH Palmer, FS Varghese, RP Van Rij
72018
Insect virus discovery by metagenomic and cell culture-based approaches
FS Varghese, RP van Rij
Viral Metagenomics: Methods and Protocols, 197-213, 2018
72018
Posaconazole inhibits multiple steps of the alphavirus replication cycle
FS Varghese, F Meutiawati, M Teppor, S Jacobs, C de Keyzer, ...
Antiviral research 197, 105223, 2022
52022
Posaconazole is a novel inhibitor for alphavirus viral entry
FS Varghese, F Meutiawati, M Teppor, A Merits, RP Rij
Access Microbiology 1 (10), 41, 2019
42019
Cracking the code of chikungunya virus: inhibitors as tools to explore alphavirus biology
FS Varghese
Helsingin yliopisto, 2016
12016
Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro (preprint)
FS Varghese, E van Woudenbergh, GJ Overheul, MJ Eleveld, L Kurver, ...
2020
Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses (preprint)
K Kistler, T Bedford, A Undale, K Arora, NM Arora, BPD Purkayastha, ...
2020
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