Cyclopentane-forming di/sesterterpene synthases: widely distributed enzymes in bacteria, fungi, and plants A Minami, T Ozaki, C Liu, H Oikawa Natural product reports 35 (12), 1330-1346, 2018 | 118 | 2018 |
5-Alkyl-1, 2, 3, 4-tetrahydroquinolines, new membrane-interacting lipophilic metabolites produced by combined culture of Streptomyces nigrescens and Tsukamurella pulmonis R Sugiyama, S Nishimura, T Ozaki, S Asamizu, H Onaka, H Kakeya Organic letters 17 (8), 1918-1921, 2015 | 79 | 2015 |
NovQ is a prenyltransferase capable of catalyzing the addition of a dimethylallyl group to both phenylpropanoids and flavonoids T Ozaki, S Mishima, M Nishiyama, T Kuzuyama The Journal of Antibiotics 62 (7), 385-392, 2009 | 79 | 2009 |
Efficient Reconstitution of Basidiomycota Diterpene Erinacine Gene Cluster in Ascomycota Host Aspergillus oryzae Based on Genomic DNA Sequences C Liu, A Minami, T Ozaki, J Wu, H Kawagishi, J Maruyama, H Oikawa Journal of the American Chemical Society 141 (39), 15519-15523, 2019 | 69 | 2019 |
Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo T Ozaki, K Yamashita, Y Goto, M Shimomura, S Hayashi, S Asamizu, ... Nature communications 8 (1), 14207, 2017 | 67 | 2017 |
Unveiling biosynthesis of the phytohormone abscisic acid in fungi: unprecedented mechanism of core scaffold formation catalyzed by an unusual sesquiterpene synthase J Takino, T Kozaki, Y Sato, C Liu, T Ozaki, A Minami, H Oikawa Journal of the American Chemical Society 140 (39), 12392-12395, 2018 | 62 | 2018 |
Genome mining reveals a minimum gene set for the biosynthesis of 32-membered macrocyclic thiopeptides lactazoles S Hayashi, T Ozaki, S Asamizu, H Ikeda, S Ōmura, N Oku, Y Igarashi, ... Chemistry & biology 21 (5), 679-688, 2014 | 60 | 2014 |
Focused genome mining of structurally related sesterterpenes: enzymatic formation of enantiomeric and diastereomeric products K Narita, H Sato, A Minami, K Kudo, L Gao, C Liu, T Ozaki, M Kodama, ... Organic letters 19 (24), 6696-6699, 2017 | 56 | 2017 |
Ascomycete Aspergillus oryzae is an efficient expression host for production of basidiomycete terpenes by using genomic DNA sequences S Nagamine, C Liu, J Nishishita, T Kozaki, K Sogahata, Y Sato, A Minami, ... Applied and environmental microbiology 85 (15), e00409-19, 2019 | 53 | 2019 |
Discovery and total synthesis of streptoaminals: antimicrobial [5, 5]‐spirohemiaminals from the combined‐culture of Streptomyces nigrescens and Tsukamurella pulmonis R Sugiyama, S Nishimura, T Ozaki, S Asamizu, H Onaka, H Kakeya Angewandte Chemie 128 (35), 10434-10438, 2016 | 48 | 2016 |
Novel tryptophan metabolism by a potential gene cluster that is widely distributed among actinomycetes T Ozaki, M Nishiyama, T Kuzuyama Journal of Biological Chemistry 288 (14), 9946-9956, 2013 | 48 | 2013 |
Insights into the biosynthesis of dehydroalanines in goadsporin T Ozaki, Y Kurokawa, S Hayashi, N Oku, S Asamizu, Y Igarashi, H Onaka ChemBioChem 17 (3), 218-223, 2016 | 46 | 2016 |
Acyltransferase that catalyses the condensation of polyketide and peptide moieties of goadvionin hybrid lipopeptides R Kozakai, T Ono, S Hoshino, H Takahashi, Y Katsuyama, Y Sugai, ... Nature chemistry 12 (9), 869-877, 2020 | 44 | 2020 |
Heterologous production of asperipin-2a: proposal for sequential oxidative macrocyclization by a fungi-specific DUF3328 oxidase Y Ye, T Ozaki, M Umemura, C Liu, A Minami, H Oikawa Organic & biomolecular chemistry 17 (1), 39-43, 2019 | 44 | 2019 |
Biosynthetic machinery of diterpene pleuromutilin isolated from basidiomycete fungi M Yamane, A Minami, C Liu, T Ozaki, I Takeuchi, T Tsukagoshi, ... ChemBioChem 18 (23), 2317-2322, 2017 | 44 | 2017 |
Minimal lactazole scaffold for in vitro thiopeptide bioengineering AA Vinogradov, M Shimomura, Y Goto, T Ozaki, S Asamizu, Y Sugai, ... Nature communications 11 (1), 2272, 2020 | 42 | 2020 |
Structural insights into the CotB2-catalyzed cyclization of geranylgeranyl diphosphate to the diterpene cyclooctat-9-en-7-ol T Tomita, SY Kim, K Teramoto, A Meguro, T Ozaki, A Yoshida, ... ACS chemical biology 12 (6), 1621-1628, 2017 | 39 | 2017 |
Killing of mycolic acid-containing bacteria aborted induction of antibiotic production by Streptomyces in combined-culture S Asamizu, T Ozaki, K Teramoto, K Satoh, H Onaka PloS one 10 (11), e0142372, 2015 | 39 | 2015 |
Cyclolavandulyl Skeleton Biosynthesis via Both Condensation and Cyclization Catalyzed by an Unprecedented Member of the cis-Isoprenyl Diphosphate Synthase … T Ozaki, P Zhao, T Shinada, M Nishiyama, T Kuzuyama Journal of the American Chemical Society 136 (13), 4837-4840, 2014 | 39 | 2014 |
Biosynthetic origin of the hydroxamic acid moiety of trichostatin A: identification of unprecedented enzymatic machinery involved in hydroxylamine transfer K Kudo, T Ozaki, K Shin-Ya, M Nishiyama, T Kuzuyama Journal of the American Chemical Society 139 (20), 6799-6802, 2017 | 34 | 2017 |