フォロー
Akitsu Hotta, Ph.D.
Akitsu Hotta, Ph.D.
Center for iPS Cell Research & Application (CiRA), Kyoto University
確認したメール アドレス: cira.kyoto-u.ac.jp - ホームページ
タイトル
引用先
引用先
Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
SJ Kattman, AD Witty, M Gagliardi, NC Dubois, M Niapour, A Hotta, J Ellis, ...
Cell stem cell 8 (2), 228-240, 2011
13432011
Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9
HL Li, N Fujimoto, N Sasakawa, S Shirai, T Ohkame, T Sakuma, ...
Stem cell reports 4 (1), 143-154, 2015
6452015
Targeted disruption of HLA genes via CRISPR-Cas9 generates iPSCs with enhanced immune compatibility
H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, ...
Cell Stem Cell 24 (4), 566-578. e7, 2019
4282019
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency
A Hotta, AYL Cheung, N Farra, K Vijayaragavan, CA Séguin, JS Draper, ...
Nature methods 6 (5), 370-376, 2009
3722009
Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a nonhuman primate
A Morizane, D Doi, T Kikuchi, K Okita, A Hotta, T Kawasaki, T Hayashi, ...
Stem Cell Reports 1 (4), 283-292, 2013
3122013
Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
AYL Cheung, LM Horvath, D Grafodatskaya, P Pasceri, R Weksberg, ...
Human molecular genetics 20 (11), 2103-2115, 2011
3032011
Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro
A Tanaka, K Woltjen, K Miyake, A Hotta, M Ikeya, T Yamamoto, T Nishino, ...
PloS one 8 (4), e61540, 2013
2462013
Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro
A Tanaka, K Woltjen, K Miyake, A Hotta, M Ikeya, T Yamamoto, T Nishino, ...
PLoS One 8 (4), e61540, 2013
2462013
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis
K Imamura, Y Izumi, A Watanabe, K Tsukita, K Woltjen, T Yamamoto, ...
Science Translational Medicine 9 (391), eaaf3962, 2017
2332017
Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping
P Gee, MSY Lung, Y Okuzaki, N Sasakawa, T Iguchi, Y Makita, H Hozumi, ...
Nature communications 11 (1), 1-18, 2020
2302020
Hair follicle dermal stem cells regenerate the dermal sheath, repopulate the dermal papilla, and modulate hair type
W Rahmani, S Abbasi, A Hagner, E Raharjo, R Kumar, A Hotta, ...
Developmental cell 31 (5), 543-558, 2014
2282014
Retroviral vector silencing during iPS cell induction: an epigenetic beacon that signals distinct pluripotent states
A Hotta, J Ellis
Journal of cellular biochemistry 105 (4), 940-948, 2008
2152008
Constitutive heterochromatin reorganization during somatic cell reprogramming
E Fussner, U Djuric, M Strauss, A Hotta, C Perez‐Iratxeta, F Lanner, ...
The EMBO journal 30 (9), 1778-1789, 2011
1692011
Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model
IY Choi, HT Lim, K Estrellas, J Mula, TV Cohen, Y Zhang, CJ Donnelly, ...
Cell reports 15 (10), 2301-2312, 2016
1622016
Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells
Y Kojima, K Sasaki, S Yokobayashi, Y Sakai, T Nakamura, Y Yabuta, ...
Cell Stem Cell 21 (4), 517-532. e5, 2017
1572017
Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice
T Kondo, M Funayama, K Tsukita, A Hotta, A Yasuda, S Nori, S Kaneko, ...
Stem cell reports 3 (2), 242-249, 2014
1552014
CRISPR-Cas3 induces broad and unidirectional genome editing in human cells
H Morisaka, K Yoshimi, Y Okuzaki, P Gee, Y Kunihiro, E Sonpho, H Xu, ...
Nature communications 10 (1), 1-13, 2019
1442019
From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing
A Hotta, S Yamanaka
Annual Review of Genetics 49, 47-70, 2015
1362015
Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy
A Minagawa, T Yoshikawa, M Yasukawa, A Hotta, M Kunitomo, S Iriguchi, ...
Cell stem cell 23 (6), 850-858. e4, 2018
1292018
Cell-type-specific genome editing with a microRNA-responsive CRISPR–Cas9 switch
M Hirosawa, Y Fujita, CJC Parr, K Hayashi, S Kashida, A Hotta, K Woltjen, ...
Nucleic acids research 45 (13), e118-e118, 2017
1082017
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