フォロー
Michael Riscoe
Michael Riscoe
Research Career Scientist, Portland VA Medical Center and Professor, Dept. of Mol. Microbiology and Immunology, Oregon Health &
確認したメール アドレス: ohsu.edu
タイトル
引用先
引用先
Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening
M Smilkstein, N Sriwilaijaroen, JX Kelly, P Wilairat, M Riscoe
Antimicrobial agents and chemotherapy 48 (5), 1803-1806, 2004
12562004
Chemical genetics of Plasmodium falciparum
WA Guiguemde, AA Shelat, D Bouck, S Duffy, GJ Crowther, PH Davis, ...
Nature 465 (7296), 311-315, 2010
6442010
Quinolone-3-diarylethers: a new class of antimalarial drug
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
Science translational medicine 5 (177), 177ra37-177ra37, 2013
2452013
Discovery of dual function acridones as a new antimalarial chemotype
JX Kelly, MJ Smilkstein, R Brun, S Wittlin, RA Cooper, KD Lane, ...
Nature 459 (7244), 270-273, 2009
2102009
Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis
JS Doggett, A Nilsen, I Forquer, KW Wegmann, L Jones-Brando, ...
Proceedings of the National Academy of Sciences 109 (39), 15936-15941, 2012
1952012
A Chloroquine-like Molecule Designed to Reverse Resistance in Plasmodium falciparum
SJ Burgess, A Selzer, JX Kelly, MJ Smilkstein, MK Riscoe, DH Peyton
Journal of medicinal chemistry 49 (18), 5623-5625, 2006
1922006
Antimalarial quinolones: synthesis, potency, and mechanistic studies
RW Winter, JX Kelly, MJ Smilkstein, R Dodean, D Hinrichs, MK Riscoe
Experimental parasitology 118 (4), 487-497, 2008
1902008
Xanthones as antimalarial agents; studies of a possible mode of action
MV Ignatushchenko, RW Winter, HP Bächinger, DJ Hinrichs, MK Riscoe
FEBS letters 409 (1), 67-73, 1997
1551997
Evaluation and lead optimization of anti-malarial acridones
RW Winter, JX Kelly, MJ Smilkstein, R Dodean, GC Bagby, RK Rathbun, ...
Experimental parasitology 114 (1), 47-56, 2006
1402006
Xanthones as antimalarial agents: discovery, mode of action, and optimization
M Riscoe, JX Kelly, R Winter
Current medicinal chemistry 12 (21), 2539-2549, 2005
1352005
Discovery, Synthesis, and Optimization of Antimalarial 4(1H)-Quinolone-3-Diarylethers
A Nilsen, GP Miley, IP Forquer, MW Mather, K Katneni, Y Li, S Pou, ...
Journal of medicinal chemistry 57 (9), 3818-3834, 2014
1222014
Optimization of endochin-like quinolones for antimalarial activity
R Winter, JX Kelly, MJ Smilkstein, D Hinrichs, DR Koop, MK Riscoe
Experimental parasitology 127 (2), 545-551, 2011
1082011
Structure of E. coli 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases
JE Lee, KA Cornell, MK Riscoe, PL Howell
Structure 9 (10), 941-953, 2001
1042001
Characterization of RecombinantEschericha coli5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase: Analysis of Enzymatic Activity and Substrate Specificity
KA Cornell, WE Swarts, RD Barry, MK Riscoe
Biochemical and biophysical research communications 228 (3), 724-732, 1996
971996
Xanthones as antimalarial agents: stage specificity.
MV Ignatushchenko, RW Winter, M Riscoe
The American journal of tropical medicine and hygiene 62 (1), 77-81, 2000
942000
Structural Rationale for the Affinity of Pico-and Femtomolar Transition State Analogues of Escherichia coli 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase*♦
JE Lee, V Singh, GB Evans, PC Tyler, RH Furneaux, KA Cornell, ...
Journal of Biological Chemistry 280 (18), 18274-18282, 2005
932005
Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes
JM Boitz, CA Gilroy, TD Olenyik, D Paradis, J Perdeh, K Dearman, ...
Infection and immunity 85 (1), 10.1128/iai. 00554-16, 2017
882017
Potentiation of the antimalarial agent rufigallol
RW Winter, KA Cornell, LL Johnson, M Ignatushchenko, DJ Hinrichs, ...
Antimicrobial agents and chemotherapy 40 (6), 1408-1411, 1996
881996
Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone
LA Lawres, A Garg, V Kumar, I Bruzual, IP Forquer, I Renard, AZ Virji, ...
Journal of Experimental Medicine 213 (7), 1307-1318, 2016
842016
α lipoic acid inhibits human T‐cell migration: Implications for multiple sclerosis
GH Marracci, GP McKeon, WE Marquardt, RW Winter, MK Riscoe, ...
Journal of neuroscience research 78 (3), 362-370, 2004
792004
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論文 1–20