Binding of Cardiac Troponin-I147-163 Induces a Structural Opening in Human Cardiac Troponin-C, MX Li, L Spyracopoulos, BD Sykes Biochemistry 38 (26), 8289-8298, 1999 | 362 | 1999 |
Structures of the troponin C regulatory domains in the apo and calcium-saturated states SM Gagné, S Tsuda, MX Li, LB Smillie, BD Sykes Nature structural biology 2 (9), 784-789, 1995 | 312 | 1995 |
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain SK Sia, MX Li, L Spyracopoulos, SM Gagné, W Liu, JA Putkey, BD Sykes Journal of Biological Chemistry 272 (29), 18216-18221, 1997 | 272 | 1997 |
Calcium-Induced Structural Transition in the Regulatory Domain of Human Cardiac Troponin C, L Spyracopoulos, MX Li, SK Sia, SM Gagné, M Chandra, RJ Solaro, ... Biochemistry 36 (40), 12138-12146, 1997 | 260 | 1997 |
Quantification of the calcium‐induced secondary structural changes in the regulatory domain of troponin‐C SM Gagné, S Tsuda, MX Li, M Chandra, LB Smillie, BD Sykes Protein Science 3 (11), 1961-1974, 1994 | 194 | 1994 |
Elemental composition of secretory granules in pancreatic islets of Langerhans MC Foster, RD Leapman, MX Li, I Atwater Biophysical journal 64 (2), 525-532, 1993 | 180 | 1993 |
Structural based insights into the role of troponin in cardiac muscle pathophysiology MX Li, X Wang, BD Sykes Journal of Muscle Research & Cell Motility 25, 559-579, 2004 | 176 | 2004 |
Dupilumab in adolescents with uncontrolled moderate‐to‐severe atopic dermatitis: results from a phase IIa open‐label trial and subsequent phase III open‐label extension MJ Cork, D Thaçi, LF Eichenfield, PD Arkwright, T Hultsch, JD Davis, ... British Journal of Dermatology 182 (1), 85-96, 2020 | 146 | 2020 |
Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 Å resolution NCJ Strynadka, M Cherney, AR Sielecki, MX Li, LB Smillie, MNG James Journal of molecular biology 273 (1), 238-255, 1997 | 144 | 1997 |
Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugs MX Li, PM Hwang Gene 571 (2), 153-166, 2015 | 143 | 2015 |
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia RL McLaughlin, D Schijven, W Van Rheenen, KR Van Eijk, M O’brien, ... Nature communications 8 (1), 14774, 2017 | 142 | 2017 |
Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins SM Gagné, MX Li, BD Sykes Biochemistry 36 (15), 4386-4392, 1997 | 135 | 1997 |
Serum resistin correlates with central obesity but weakly with insulin resistance in Chinese children and adolescents M Li, A Fisette, XY Zhao, JY Deng, J Mi, K Cianflone International journal of obesity 33 (4), 424-439, 2009 | 121 | 2009 |
White-matter microstructure in previously drug-naive patients with schizophrenia after 6 weeks of treatment Q Wang, C Cheung, W Deng, M Li, C Huang, X Ma, Y Wang, L Jiang, ... Psychological medicine 43 (11), 2301-2309, 2013 | 114 | 2013 |
Calcium binding to the regulatory N-domain of skeletal muscle troponin C occurs in a stepwise manner MX Li, SM Gagne, S Tsuda, CM Kay, LB Smillie, BD Sykes Biochemistry 34 (26), 8330-8340, 1995 | 112 | 1995 |
Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147–163 and bepridil X Wang, MX Li, BD Sykes Journal of Biological Chemistry 277 (34), 31124-31133, 2002 | 103 | 2002 |
Five endometrial cancer risk loci identified through genome-wide association analysis THT Cheng, DJ Thompson, TA O'Mara, JN Painter, DM Glubb, S Flach, ... Nature genetics 48 (6), 667-674, 2016 | 100 | 2016 |
Common variants on 2p16. 1, 6p22. 1 and 10q24. 32 are associated with schizophrenia in Han Chinese population H Yu, H Yan, J Li, Z Li, X Zhang, Y Ma, L Mei, C Liu, L Cai, Q Wang, ... Molecular psychiatry 22 (7), 954-960, 2017 | 93 | 2017 |
A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex IM Robertson, YB Sun, MX Li, BD Sykes Journal of molecular and cellular cardiology 49 (6), 1031-1041, 2010 | 92 | 2010 |
Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033 X Wang, MX Li, L Spyracopoulos, N Beier, M Chandra, RJ Solaro, ... Journal of Biological Chemistry 276 (27), 25456-25466, 2001 | 87 | 2001 |