Sebastian Brandner
Sebastian Brandner
Professor of Neuropathology, UCL
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Cited by
Cited by
Prion protein (PrP) with amino‐proximal deletions restoring susceptibility of PrP knockout mice to scrapie.
M Fischer, T Rülicke, A Raeber, A Sailer, M Moser, B Oesch, S Brandner, ...
The EMBO journal 15 (6), 1255-1264, 1996
Normal host prion protein necessary for scrapie-induced neurotoxicity
S Brandner, S Isenmann, A Raeber, M Fischer, A Sailer, Y Kobayashi, ...
Nature 379 (6563), 339-343, 1996
Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
G Skibinski, NJ Parkinson, JM Brown, L Chakrabarti, SL Lloyd, ...
Nature genetics 37 (8), 806-808, 2005
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
G Mallucci, A Dickinson, J Linehan, PC Klöhn, S Brandner, J Collinge
Science 302 (5646), 871-874, 2003
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
D Shmerling, I Hegyi, M Fischer, T Blättler, S Brandner, J Götz, T Rülicke, ...
Cell 93 (2), 203-214, 1998
Monoclonal antibodies inhibit prion replication and delay the development of prion disease
AR White, P Enever, M Tayebi, R Mushens, J Linehan, S Brandner, ...
Nature 422 (6927), 80-83, 2003
DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469-474, 2018
Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report
SJ Wroe, S Pal, D Siddique, H Hyare, R Macfarlane, S Joiner, JM Linehan, ...
The Lancet 368 (9552), 2061-2067, 2006
An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes
A O'Doherty, S Ruf, C Mulligan, V Hildreth, ML Errington, S Cooke, ...
Science 309 (5743), 2033-2037, 2005
Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice
LM Martins, A Morrison, K Klupsch, V Fedele, N Moisoi, P Teismann, ...
Molecular and cellular biology 24 (22), 9848-9862, 2004
Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma
JA Kraus, J Koopmann, P Kaskel, D Maintz, S Brandner, J Schramm, ...
Journal of Neuropathology & Experimental Neurology 54 (1), 91-95, 1995
Behavioral and anatomical deficits in mice homozygous for a modified β-amyloid precursor protein gene
U Müller, N Cristina, ZW Li, DP Wolfer, HP Lipp, T Rülicke, S Brandner, ...
Cell 79 (5), 755-765, 1994
Neuropathology E-book: a reference text of CNS pathology
D Ellison, S Love, LMC Chimelli, B Harding, JS Lowe, HV Vinters, ...
Elsevier Health Sciences, 2012
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain
T Blättler, S Brandner, AJ Raeber, MA Klein, T Voigtländer, C Weissmann, ...
Nature 389 (6646), 69-73, 1997
Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy
Z Jaunmuktane, S Mead, M Ellis, JDF Wadsworth, AJ Nicoll, J Kenny, ...
Nature 525 (7568), 247-250, 2015
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system
S Brandner, A Raeber, A Sailer, T Blättler, M Fischer, C Weissmann, ...
Proceedings of the National Academy of Sciences 93 (23), 13148-13151, 1996
Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey
ON Gill, Y Spencer, A Richard-Loendt, C Kelly, R Dabaghian, L Boyes, ...
Bmj 347, f5675, 2013
Human prion protein with valine 129 prevents expression of variant CJD phenotype
JDF Wadsworth, EA Asante, M Desbruslais, JM Linehan, S Joiner, ...
Science 306 (5702), 1793-1796, 2004
Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice
GR Mallucci, MD White, M Farmer, A Dickinson, H Khatun, AD Powell, ...
Neuron 53 (3), 325-335, 2007
Early‐onset L‐dopa‐responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations
C Paisán‐Ruiz, R Guevara, M Federoff, H Hanagasi, F Sina, E Elahi, ...
Movement Disorders 25 (12), 1791-1800, 2010
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