VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death D Lambrechts, E Storkebaum, M Morimoto, J Del-Favero, F Desmet, ... Nature genetics 34 (4), 383-394, 2003 | 1116 | 2003 |
A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA T Kadowaki, H Kadowaki, Y Mori, K Tobe, R Sakuta, Y Suzuki, Y Tanabe, ... New England Journal of Medicine 330 (14), 962-968, 1994 | 759 | 1994 |
A common polymorphism in the 5′-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes T Awata, K Inoue, S Kurihara, T Ohkubo, M Watanabe, K Inukai, I Inoue, ... Diabetes 51 (5), 1635-1639, 2002 | 750 | 2002 |
Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of mRNA levels for interleukin-1β, interleukin-6, cyclooxygenase-2, and p22phox by regulation … I Inoue, S Goto, K Mizotani, T Awata, T Mastunaga, S Kawai, T Nakajima, ... Life sciences 67 (8), 863-876, 2000 | 433 | 2000 |
Expression of peroxisome proliferator-activated receptor α (PPARα) in primary cultures of human vascular endothelial cells I Inoue, K Shino, S Noji, T Awata, S Katayama Biochemical and biophysical research communications 246 (2), 370-374, 1998 | 411 | 1998 |
The ligands/activators for peroxisome proliferator-activated receptor α (PPARα) and PPARγ increase Cu2+, Zn2+-superoxide dismutase and decrease p22phox message expressions in … I Inoue, S Goto, T Matsunaga, T Nakajima, T Awata, S Hokari, T Komoda, ... Metabolism-Clinical and Experimental 50 (1), 3-11, 2001 | 358 | 2001 |
The Pro12→ Ala substitution in PPAR-γ is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin … H Mori, H Ikegami, Y Kawaguchi, S Seino, N Yokoi, J Takeda, I Inoue, ... Diabetes 50 (4), 891-894, 2001 | 355 | 2001 |
Report of the Committee of the Japan Diabetes Society on the research of fulminant and acute-onset type 1 diabetes mellitus: new diagnostic criteria of fulminant type 1 … A Imagawa, T Hanafusa, T Awata, H Ikegami, Y Uchigata, H Osawa, ... Diabetology international 3, 179-183, 2012 | 260 | 2012 |
Effect of new oral antidiabetic agent CS-045 on glucose tolerance and insulin secretion in patients with NIDDM Y Iwamoto, T Kuzuya, A Matsuda, T Awata, S Kumakura, G Inooka, ... Diabetes Care 14 (11), 1083-1086, 1991 | 253 | 1991 |
Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis FK Kavvoura, T Akamizu, T Awata, Y Ban, DA Chistiakov, I Frydecka, ... The Journal of Clinical Endocrinology & Metabolism 92 (8), 3162-3170, 2007 | 238 | 2007 |
Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): Association between a promoter polymorphism and … E Kawasaki, T Awata, H Ikegami, T Kobayashi, T Maruyama, K Nakanishi, ... American journal of medical genetics Part A 140 (6), 586-593, 2006 | 207 | 2006 |
Association of CTLA-4 gene AG polymorphism (IDDM12 locus) with acute-onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hashimoto's … T Awata, S Kurihara, M Iitaka, S Takei, I Inoue, C Ishii, K Negishi, ... Diabetes 47 (1), 128-129, 1998 | 201 | 1998 |
Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes T Awata, S Kurihara, N Takata, T Neda, H Iizuka, T Ohkubo, M Osaki, ... Biochemical and biophysical research communications 333 (3), 679-685, 2005 | 167 | 2005 |
CLOCK/BMAL1 is involved in lipid metabolism via transactivation of the peroxisome proliferator-activated receptor (PPAR) response element I Inoue, Y Shinoda, M Ikeda, K Hayashi, K Kanazawa, M Nomura, ... Journal of atherosclerosis and thrombosis 12 (3), 169-174, 2005 | 167 | 2005 |
Differential association of HLA with three subtypes of type 1 diabetes: fulminant, slowly progressive and acute-onset Y Kawabata, H Ikegami, T Awata, A Imagawa, T Maruyama, E Kawasaki, ... Diabetologia 52, 2513-2521, 2009 | 152 | 2009 |
Regulation of adiponectin receptor gene expression in diabetic mice K Inukai, Y Nakashima, M Watanabe, N Takata, T Sawa, S Kurihara, ... American Journal of Physiology-Endocrinology and Metabolism 288 (5), E876-E882, 2005 | 152 | 2005 |
Fibrate and statin synergistically increase the transcriptional activities of PPARα/RXRα and decrease the transactivation of NFκB I Inoue, F Itoh, S Aoyagi, S Tazawa, H Kusama, M Akahane, T Mastunaga, ... Biochemical and biophysical research communications 290 (1), 131-139, 2002 | 147 | 2002 |
High frequency of aspartic acid at position 57 of HLA-DQ β-chain in Japanese IDDM patients and nondiabetic subjects T Awata, T Kuzuya, A Matsuda, Y Iwamoto, Y Kanazawa, M Okuyama, ... Diabetes 39 (2), 266-269, 1990 | 142 | 1990 |
Endothelial nitric oxide synthase gene is associated with diabetic macular edema in type 2 diabetes T Awata, T Neda, H Iizuka, S Kurihara, T Ohkubo, N Takata, M Osaki, ... Diabetes care 27 (9), 2184-2190, 2004 | 135 | 2004 |
Free immunoglobulin light chain: its biology and implications in diseases T Nakano, M Matsui, I Inoue, T Awata, S Katayama, T Murakoshi Clinica Chimica Acta 412 (11-12), 843-849, 2011 | 125 | 2011 |