Teruki Honma
Teruki Honma
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A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
M Okada-Iwabu, T Yamauchi, M Iwabu, T Honma, K Hamagami, ...
Nature 503 (7477), 493-499, 2013
Structure-Based Generation of a New Class of Potent Cdk4 Inhibitors:  New de Novo Design Strategy and Library Design
T Honma, K Hayashi, T Aoyama, N Hashimoto, T Machida, K Fukasawa, ...
Journal of Medicinal Chemistry 44 (26), 4615-4627, 2001
Structure of the trypanosome cyanide-insensitive alternative oxidase
T Shiba, Y Kido, K Sakamoto, DK Inaoka, C Tsuge, R Tatsumi, ...
Proceedings of the National Academy of Sciences 110 (12), 4580-4585, 2013
A novel approach for the development of selective Cdk4 inhibitors: library design based on locations of Cdk4 specific amino acid residues
T Honma, T Yoshizumi, N Hashimoto, K Hayashi, N Kawanishi, ...
Journal of medicinal chemistry 44 (26), 4628-4640, 2001
Structural basis for chemical inhibition of human blood coagulation factor Xa
K Kamata, H Kawamoto, T Honma, T Iwama, SH Kim
Proceedings of the National Academy of Sciences 95 (12), 6630-6635, 1998
The translation inhibitor rocaglamide targets a bimolecular cavity between eIF4A and polypurine RNA
S Iwasaki, W Iwasaki, M Takahashi, A Sakamoto, C Watanabe, Y Shichino, ...
Molecular cell 73 (4), 738-748. e9, 2019
Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein
M Ikuta, K Kamata, K Fukasawa, T Honma, T Machida, H Hirai, ...
Journal of Biological Chemistry 276 (29), 27548-27554, 2001
Practical synthesis of indolopyrrolocarbazoles
M Ohkubo, T Nishimura, H Jona, T Honma, H Morishima
Tetrahedron 52 (24), 8099-8112, 1996
Combining machine learning and pharmacophore-based interaction fingerprint for in silico screening
T Sato, T Honma, S Yokoyama
Journal of chemical information and modeling 50 (1), 170-185, 2010
Population-based de novo molecule generation, using grammatical evolution
N Yoshikawa, K Terayama, M Sumita, T Homma, K Oono, K Tsuda
Chemistry Letters 47 (11), 1431-1434, 2018
Predicting human liver microsomal stability with machine learning techniques
Y Sakiyama, H Yuki, T Moriya, K Hattori, M Suzuki, K Shimada, T Honma
Journal of molecular graphics and Modelling 26 (6), 907-915, 2008
Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2
A Nishikimi, T Uruno, X Duan, Q Cao, Y Okamura, T Saitoh, N Saito, ...
Chemistry & biology 19 (4), 488-497, 2012
A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo
Y Saito, H Yuki, M Kuratani, Y Hashizume, S Takagi, T Honma, A Tanaka, ...
Science translational medicine 5 (181), 181ra52-181ra52, 2013
Recent advances in de novo design strategy for practical lead identification
T Honma
Medicinal research reviews 23 (5), 606-632, 2003
Structural insights into the molecular design of flutolanil derivatives targeted for fumarate respiration of parasite mitochondria
DK Inaoka, T Shiba, D Sato, EO Balogun, T Sasaki, M Nagahama, M Oda, ...
International journal of molecular sciences 16 (7), 15287-15308, 2015
Targeting Ras-driven cancer cell survival and invasion through selective inhibition of DOCK1
H Tajiri, T Uruno, T Shirai, D Takaya, S Matsunaga, D Setoyama, ...
Cell reports 19 (5), 969-980, 2017
kGCN: a graph-based deep learning framework for chemical structures
R Kojima, S Ishida, M Ohta, H Iwata, T Honma, Y Okuno
Journal of Cheminformatics 12, 1-10, 2020
Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase
H Shimizu, A Saito, J Mikuni, EE Nakayama, H Koyama, T Honma, ...
PLoS neglected tropical diseases 13 (11), e0007894, 2019
Total synthesis of (+)-obtusenyne
K Fujiwara, D Awakura, M Tsunashima, A Nakamura, T Honma, A Murai
The Journal of Organic Chemistry 64 (8), 2616-2617, 1999
Synthesis of dissymmetric indolocarbazole glycosides using the Mitsunobu reaction at the glycosylation step
M Ohkubo, T Nishimura, H Jona, T Honma, S Ito, H Morishima
Tetrahedron 53 (17), 5937-5950, 1997
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