| A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development A Kamiya, K Kubo, T Tomoda, M Takaki, R Youn, Y Ozeki, N Sawamura, ... Nature cell biology 7 (12), 1167-1178, 2005 | 658 | 2005 |
| Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice JS Gong, M Kobayashi, H Hayashi, K Zou, N Sawamura, SC Fujita, ... Journal of Biological Chemistry 277 (33), 29919-29926, 2002 | 272 | 2002 |
| Amyloid β protein in plasma from patients with sporadic Alzheimer's disease A Tamaoka, T Fukushima, N Sawamura, K Ishikawa, E Oguni, ... Journal of the neurological sciences 141 (1-2), 65-68, 1996 | 207 | 1996 |
| Amyloid β protein 42 (43) in cerebrospinal fluid of patients with Alzheimer's disease A Tamaoka, N Sawamura, T Fukushima, E Matsubara, M Shoji, S Hirai, ... Journal of the neurological sciences 148 (1), 41-45, 1997 | 203 | 1997 |
| Amyloid β‐protein (Aβ) 1–40 protects neurons from damage induced by Aβ1–42 in culture and in rat brain K Zou, D Kim, A Kakio, K Byun, JS Gong, J Kim, M Kim, N Sawamura, ... Journal of neurochemistry 87 (3), 609-619, 2003 | 199 | 2003 |
| A novel action of Alzheimer's amyloid β-protein (Aβ): oligomeric Aβ promotes lipid release M Michikawa, JS Gong, QW Fan, N Sawamura, K Yanagisawa Journal of Neuroscience 21 (18), 7226-7235, 2001 | 192 | 2001 |
| Biochemical evidence for the long-tail form (Aβ1-42/43) of amyloid β protein as a seed molecule in cerebral deposits of alzheimer′ s disease A Tamaoka, T Kondo, A Odaka, N Sahara, N Sawamura, K Ozawa, ... Biochemical and biophysical research communications 205 (1), 834-842, 1994 | 149 | 1994 |
| Cholesterol‐dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons QW Fan, W Yu, JS Gong, K Zou, N Sawamura, T Senda, K Yanagisawa, ... Journal of neurochemistry 80 (1), 178-190, 2002 | 146 | 2002 |
| Mutant presenilin 2 transgenic mouse: effect on an age‐dependent increase of amyloid β‐protein 42 in the brain F Oyama, N Sawamura, K Kobayashi, M Morishima‐Kawashima, ... Journal of neurochemistry 71 (1), 313-322, 1998 | 142 | 1998 |
| Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice N Sawamura, JS Gong, WS Garver, RA Heidenreich, H Ninomiya, K Ohno, ... Journal of Biological Chemistry 276 (13), 10314-10319, 2001 | 132 | 2001 |
| Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly N Sawamura, T Ando, Y Maruyama, M Fujimuro, H Mochizuki, K Honjo, ... Molecular psychiatry 13 (12), 1138-1148, 2008 | 129 | 2008 |
| A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse N Sawamura, T Sawamura-Yamamoto, Y Ozeki, CA Ross, A Sawa Proceedings of the National Academy of Sciences 102 (4), 1187-1192, 2005 | 127 | 2005 |
| Modulation of amyloid precursor protein cleavage by cellular sphingolipids N Sawamura, M Ko, W Yu, K Zou, K Hanada, T Suzuki, JS Gong, ... Journal of Biological Chemistry 279 (12), 11984-11991, 2004 | 118 | 2004 |
| Mutant presenilin 2 transgenic mice: a large increase in the levels of Aβ42 is presumably associated with the low density membrane domain that contains decreased levels of … N Sawamura, M Morishima-Kawashima, H Waki, K Kobayashi, ... Journal of Biological Chemistry 275 (36), 27901-27908, 2000 | 112 | 2000 |
| Amyloid β protein 1–42/43 (Aβ 1–42/43) in cerebellar diffuse plaques: Enzyme-linked immunosorbent assay and immunocytochemical study A Tamaoka, N Sawamura, A Odaka, N Suzuki, H Mizusawa, H Mori Brain research 679 (1), 151-156, 1995 | 83 | 1995 |
| Amyloid β‐protein affects cholesterol metabolism in cultured neurons: implications for pivotal role of cholesterol in the amyloid cascade JS Gong, N Sawamura, K Zou, J Sakai, K Yanagisawa, M Michikawa Journal of neuroscience research 70 (3), 438-446, 2002 | 65 | 2002 |
| Disrupted‐in‐Schizophrenia‐1 (DISC1) A Key Susceptibility Factor for Major Mental Illnesses N Sawamura, A Sawa Annals of the New York Academy of Sciences 1086 (1), 126-133, 2006 | 55 | 2006 |
| Primate disrupted-in-schizophrenia-1 (DISC1): high divergence of a gene for major mental illnesses in recent evolutionary history L Bord, J Wheeler, M Paek, M Saleh, A Lyons-Warren, CA Ross, ... Neuroscience research 56 (3), 286-293, 2006 | 50 | 2006 |
| Carboxyl end-specific monoclonal antibodies to amyloid β protein (Aβ) subtypes (Aβ40 and Aβ42 (43)) differentiate Aβ in senile plaques and amyloid angiopathy in brains of aged … S Nakamura, A Tamaoka, N Sawamura, H Nakayama, F Ono, ... Neuroscience letters 201 (2), 151-154, 1995 | 49* | 1995 |
| Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent‐insoluble membrane fraction in Niemann–Pick C1‐deficient cells N Sawamura, JS Gong, TY Chang, K Yanagisawa, M Michikawa Journal of neurochemistry 84 (5), 1086-1096, 2003 | 47 | 2003 |
