Linda S Wicker
Linda S Wicker
Professor of Immunogenetics, University of Oxford
Verified email at
Cited by
Cited by
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
H Ueda, JMM Howson, L Esposito, J Heward, Snook, G Chamberlain, ...
Nature 423 (6939), 506-511, 2003
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
JA Todd, NM Walker, JD Cooper, DJ Smyth, K Downes, V Plagnol, ...
Nature genetics 39 (7), 857-864, 2007
Genetic control of autoimmune diabetes in the NOD mouse.
LS Wicker, JA Todd, LB Peterson
Annual review of immunology 13, 179-200, 1995
Genetic analysis of autoimmune type 1 diabetes mellitus in mice
JA Todd, TJ Aitman, RJ Cornall, S Ghosh, JRS Hall, CM Hearne, ...
Nature 351 (6327), 542-547, 1991
Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice.
BJ Miller, MC Appel, JJ O'neil, LS Wicker
Journal of immunology (Baltimore, Md.: 1950) 140 (1), 52-58, 1988
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
CE Lowe, JD Cooper, T Brusko, NM Walker, DJ Smyth, R Bailey, ...
Nature genetics 39 (9), 1074-1082, 2007
Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice
LS Wicker, BJ Miller, Y Mullen
Diabetes 35 (8), 855-860, 1986
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
J Yamanouchi, D Rainbow, P Serra, S Howlett, K Hunter, VES Garner, ...
Nature genetics 39 (3), 329-337, 2007
Polygenic control of autoimmune diabetes in nonobese diabetic mice
S Ghosh, SM Palmer, NR Rodrigues, HJ Cordell, CM Hearne, RJ Cornall, ...
Nature genetics 4 (4), 404-409, 1993
Photochemical preparation of a pyridone containing tetracycle: a Jak protein kinase inhibitor
JE Thompson, RM Cubbon, RT Cummings, LS Wicker, R Frankshun, ...
Bioorganic & medicinal chemistry letters 12 (8), 1219-1223, 2002
β2-microglobulin–deficient NOD mice do not develop insulitis or diabetes
LS Wicker, EH Leiter, JA Todd, RJ Renjilian, E Peterson, PA Fischer, ...
Diabetes 43 (3), 500-504, 1994
Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse.
LS Wicker, BJ Miller, LZ Coker, SE McNally, S Scott, Y Mullen, MC Appel
The Journal of experimental medicine 165 (6), 1639-1654, 1987
A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes
RC Ferreira, H Guo, RMR Coulson, DJ Smyth, ML Pekalski, OS Burren, ...
Diabetes 63 (7), 2538-2550, 2014
Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus
E Fung, DJ Smyth, JMM Howson, JD Cooper, NM Walker, H Stevens, ...
Genes & Immunity 10 (2), 188-191, 2009
Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource
CA Dendrou, V Plagnol, E Fung, JHM Yang, K Downes, JD Cooper, ...
Nature genetics 41 (9), 1011-1015, 2009
IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production
LM Maier, CE Lowe, J Cooper, K Downes, DE Anderson, C Severson, ...
PLoS genetics 5 (1), e1000322, 2009
An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells
L Vijayakrishnan, JM Slavik, Z IllÚs, RJ Greenwald, D Rainbow, B Greve, ...
Immunity 20 (5), 563-575, 2004
Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models
JA Todd, LS Wicker
Immunity 15 (3), 387-395, 2001
Liver autoimmunity triggered by microbial activation of natural killer T cells
J Mattner, PB Savage, P Leung, SS Oertelt, V Wang, O Trivedi, ...
Cell host & microbe 3 (5), 304-315, 2008
CD226 Gly307Ser association with multiple autoimmune diseases
JP Hafler, LM Maier, JD Cooper, V Plagnol, A Hinks, MJ Simmonds, ...
Genes & Immunity 10 (1), 5-10, 2009
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