| NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol S Benjannet, D Rhainds, R Essalmani, J Mayne, L Wickham, W Jin, ... Journal of Biological Chemistry 279 (47), 48865-48875, 2004 | 788 | 2004 |
| Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte‐specific low‐density lipoprotein receptor degradation and critical role in mouse liver regeneration A Zaid, A Roubtsova, R Essalmani, J Marcinkiewicz, A Chamberland, ... Hepatology 48 (2), 646-654, 2008 | 463 | 2008 |
| The activation and physiological functions of the proprotein convertases NG Seidah, G Mayer, A Zaid, E Rousselet, N Nassoury, S Poirier, ... The international journal of biochemistry & cell biology 40 (6-7), 1111-1125, 2008 | 391 | 2008 |
| Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp JL Vilotte, S Soulier, R Essalmani, MG Stinnakre, D Vaiman, L Lepourry, ... Journal of virology 75 (13), 5977-5984, 2001 | 222 | 2001 |
| In vivo evidence that furin from hepatocytes inactivates PCSK9 R Essalmani, D Susan-Resiga, A Chamberland, M Abifadel, ... Journal of Biological Chemistry 286 (6), 4257-4263, 2011 | 184 | 2011 |
| A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission V Béringue, O Andréoletti, A Le Dur, R Essalmani, JL Vilotte, C Lacroux, ... Journal of Neuroscience 27 (26), 6965-6971, 2007 | 165 | 2007 |
| VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5 D Szumska, G Pieles, R Essalmani, M Bilski, D Mesnard, K Kaur, ... Genes & development 22 (11), 1465-1477, 2008 | 158 | 2008 |
| Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver X Sun, R Essalmani, R Day, AM Khatib, NG Seidah, A Prat Neoplasia 14 (12), 1122-IN5, 2012 | 135 | 2012 |
| In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate R Essalmani, A Zaid, J Marcinkiewicz, A Chamberland, A Pasquato, ... Proceedings of the National Academy of Sciences 105 (15), 5750-5755, 2008 | 125 | 2008 |
| Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse R Essalmani, J Hamelin, J Marcinkiewicz, A Chamberland, M Mbikay, ... Molecular and Cellular Biology 26 (1), 354-361, 2006 | 113 | 2006 |
| Distinctive roles of furin and TMPRSS2 in SARS-CoV-2 infectivity R Essalmani, J Jain, D Susan-Resiga, U Andréo, A Evagelidis, ... Journal of virology 96 (8), e00128-22, 2022 | 105 | 2022 |
| Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice WC Wetsel, RM Rodriguiz, J Guillemot, E Rousselet, R Essalmani, IH Kim, ... Proceedings of the National Academy of Sciences 110 (43), 17362-17367, 2013 | 101 | 2013 |
| Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin J Guillemot, M Canuel, R Essalmani, A Prat, NG Seidah Hepatology 57 (6), 2514-2524, 2013 | 98 | 2013 |
| Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes MM Hipp, D Shepherd, U Gileadi, MC Aichinger, BM Kessler, ... Immunity 39 (4), 711-721, 2013 | 86 | 2013 |
| Effects of the prosegment and pH on the activity of PCSK9: evidence for additional processing events S Benjannet, YGL Saavedra, J Hamelin, MC Asselin, R Essalmani, ... Journal of biological chemistry 285 (52), 40965-40978, 2010 | 75 | 2010 |
| Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10 D Susan-Resiga, R Essalmani, J Hamelin, MC Asselin, S Benjannet, ... Journal of Biological Chemistry 286 (26), 22785-22794, 2011 | 72 | 2011 |
| New in vivo and ex vivo models for the experimental study of sheep scrapie: development and perspectives H Laude, D Vilette, A Le Dur, F Archer, S Soulier, N Besnard, R Essalmani, ... Comptes Rendus Biologies 325 (1), 49-57, 2002 | 66 | 2002 |
| PCSK9 deficiency unmasks a sex-and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice [S] A Roubtsova, A Chamberland, J Marcinkiewicz, R Essalmani, A Fazel, ... Journal of lipid research 56 (11), 2133-2142, 2015 | 63 | 2015 |
| Proprotein convertase furin regulates osteocalcin and bone endocrine function O Al Rifai, J Chow, J Lacombe, C Julien, D Faubert, D Susan-Resiga, ... The Journal of clinical investigation 127 (11), 4104-4117, 2017 | 61 | 2017 |
| Amyloid precursor-like protein 2 and sortilin do not regulate the PCSK9 convertase-mediated low density lipoprotein receptor degradation but interact with each other C Butkinaree, M Canuel, R Essalmani, S Poirier, S Benjannet, MC Asselin, ... Journal of Biological Chemistry 290 (30), 18609-18620, 2015 | 61 | 2015 |
Didier ViletteINRA Research Director, UMR1225 INRA-ENVT, TMBI (Univ. Toulouse)Verified email at envt.fr
