Shusuke Tomoshige
Shusuke Tomoshige
Graduate School of Life Sciences, Tohoku University
Verified email at - Homepage
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Structure–activity relationships of bisphenol A analogs at estrogen receptors (ERs): Discovery of an ERα-selective antagonist
K Maruyama, M Nakamura, S Tomoshige, K Sugita, M Makishima, ...
Bioorganic & medicinal chemistry letters 23 (14), 4031-4036, 2013
Degradation of HaloTag-fused nuclear proteins using bestatin-HaloTag ligand hybrid molecules
S Tomoshige, M Naito, Y Hashimoto, M Ishikawa
Organic & biomolecular chemistry 13 (38), 9746-9750, 2015
Discovery of small molecules that induce the degradation of huntingtin
S Tomoshige, S Nomura, K Ohgane, Y Hashimoto, M Ishikawa
Angewandte Chemie 129 (38), 11688-11691, 2017
Efficient protein knockdown of HaloTag-fused proteins using hybrid molecules consisting of IAP antagonist and HaloTag ligand
S Tomoshige, Y Hashimoto, M Ishikawa
Bioorganic & medicinal chemistry 24 (14), 3144-3148, 2016
Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa
M Lee, MT Batuecas, S Tomoshige, T Domínguez-Gil, KV Mahasenan, ...
Proceedings of the National Academy of Sciences 115 (17), 4393-4398, 2018
Total syntheses of bulgecins A, B, and C and their bactericidal potentiation of the β-Lactam antibiotics
S Tomoshige, DA Dik, M Akabane-Nakata, CS Madukoma, JF Fisher, ...
ACS infectious diseases 4 (6), 860-867, 2018
Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics
DA Dik, CS Madukoma, S Tomoshige, C Kim, E Lastochkin, WC Boggess, ...
ACS chemical biology 14 (2), 296-303, 2019
Degradation of huntingtin mediated by a hybrid molecule composed of IAP antagonist linked to phenyldiazenyl benzothiazole derivative
S Tomoshige, S Nomura, K Ohgane, Y Hashimoto, M Ishikawa
Bioorganic & Medicinal Chemistry Letters 28 (4), 707-710, 2018
Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives
Y Kusakabe, S Mizutani, S Kamo, T Yoshimoto, S Tomoshige, T Kawasaki, ...
Bioorganic & medicinal chemistry letters 29 (11), 1390-1394, 2019
Application of protein knockdown strategy targeting β-sheet structure to multiple disease-associated polyglutamine proteins
H Yamashita, S Tomoshige, S Nomura, K Ohgane, Y Hashimoto, ...
Bioorganic & Medicinal Chemistry 28 (1), 115175, 2020
Improvement in Aqueous Solubility of Retinoic Acid Receptor (RAR) Agonists by Bending the Molecular Structure
M Hiramatsu, Y Ichikawa, S Tomoshige, M Makishima, A Muranaka, ...
Chemistry–An Asian Journal 11 (15), 2210-2217, 2016
Total Syntheses of Pyocyanin, Lavanducyanin, and Marinocyanins A and B
H Kohatsu, S Kamo, S Tomoshige, K Kuramochi
Organic letters 21 (18), 7311-7314, 2019
Recent Progress in PROTACs and Other Chemical Protein Degradation Technologies for the Treatment of Neurodegenerative Disorders
S Tomoshige, M Ishikawa
Angewandte Chemie International Edition, 2020
Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs
M Ishikawa, S Tomoshige, Y Demizu, M Naito
Pharmaceuticals 13 (4), 74, 2020
Synthesis of nucleotide analogues, EFdA, EdA and EdAP, and the effect of EdAP on hepatitis B virus replication
M Kamata, T Takeuchi, E Hayashi, K Nishioka, M Oshima, M Iwamoto, ...
Bioscience, Biotechnology, and Biochemistry 84 (2), 217-227, 2020
Isolation, synthesis, and biological activities of a bibenzyl from Empetrum nigrum var. japonicum
S Oka, R Kuniba, N Tsuboi, S Tsuchida, K Ushida, S Tomoshige, ...
Bioscience, biotechnology, and biochemistry 84 (1), 31-36, 2020
Synthetic and biological studies of juglorubin and related naphthoquinones
S Kamo, T Saito, Y Kusakabe, S Tomoshige, M Uchiyama, K Tsubaki, ...
The Journal of Organic Chemistry 84 (21), 13957-13966, 2019
Synthesis and Cytotoxic Evaluation of N-Alkyl-2-halophenazin-1-ones
H Kohatsu, S Kamo, M Furuta, S Tomoshige, K Kuramochi
ACS omega 5 (42), 27667-27674, 2020
Synthesis and structural revision of an indanone isolated from Triphyophyllum peltatum
Y Ishii, M Ota, S Kamo, S Tomoshige, K Tsubaki, K Kuramochi
Tetrahedron Letters 61 (7), 151494, 2020
Dimerizations of 2-bromo-3-methyl-1, 4-naphthoquinone and 2-methyl-1, 4-naphthoquinone in tetra-n-butylammonium bromide
M Onuki, M Ota, S Otokozawa, S Kamo, S Tomoshige, K Tsubaki, ...
Tetrahedron 76 (6), 130899, 2020
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