| Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve N Uemura, H Yagi, MT Uemura, Y Hatanaka, H Yamakado, R Takahashi Molecular neurodegeneration 13, 1-11, 2018 | 259 | 2018 |
| A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats S Nuber, F Harmuth, Z Kohl, A Adame, M Trejo, K Schönig, ... Brain 136 (2), 412-432, 2013 | 154 | 2013 |
| Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation C Kim, B Spencer, E Rockenstein, H Yamakado, M Mante, A Adame, ... Molecular neurodegeneration 13, 1-18, 2018 | 133 | 2018 |
| Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type E Ihse, H Yamakado, XM van Wijk, R Lawrence, JD Esko, E Masliah Scientific reports 7 (1), 9008, 2017 | 123 | 2017 |
| α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson’s disease model T Taguchi, M Ikuno, M Hondo, LK Parajuli, K Taguchi, J Ueda, ... Brain 143 (1), 249-265, 2020 | 80 | 2020 |
| Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein N Uemura, M Koike, S Ansai, M Kinoshita, T Ishikawa-Fujiwara, H Matsui, ... PLoS genetics 11 (4), e1005065, 2015 | 74 | 2015 |
| α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion H Yamakado, Y Moriwaki, N Yamasaki, T Miyakawa, J Kurisu, K Uemura, ... Neuroscience research 73 (2), 173-177, 2012 | 61 | 2012 |
| PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates H Matsui, R Gavinio, T Asano, N Uemura, H Ito, Y Taniguchi, Y Kobayashi, ... Human molecular genetics 22 (12), 2423-2434, 2013 | 58 | 2013 |
| Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions S Kaji, T Maki, T Ishimoto, H Yamakado, R Takahashi Translational Neurodegeneration 9, 1-15, 2020 | 48 | 2020 |
| Animal model for prodromal Parkinson’s disease T Taguchi, M Ikuno, H Yamakado, R Takahashi International journal of molecular sciences 21 (6), 1961, 2020 | 46 | 2020 |
| GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson’s disease M Ikuno, H Yamakado, H Akiyama, LK Parajuli, K Taguchi, J Hara, ... Human molecular genetics 28 (11), 1894-1904, 2019 | 46 | 2019 |
| Idiopathic Parkinson's disease patient‐derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains T Kikuchi, A Morizane, D Doi, K Okita, M Nakagawa, H Yamakado, ... Journal of Neuroscience Research 95 (9), 1829-1837, 2017 | 41 | 2017 |
| α‐Synuclein Spread from Olfactory Bulb Causes Hyposmia, Anxiety, and Memory Loss in BAC‐SNCA Mice N Uemura, J Ueda, T Yoshihara, M Ikuno, MT Uemura, H Yamakado, ... Movement Disorders 36 (9), 2036-2047, 2021 | 39 | 2021 |
| Altered awareness of action in Parkinson’s disease: evaluations by explicit and implicit measures N Saito, K Takahata, H Yamakado, N Sawamoto, S Saito, R Takahashi, ... Scientific Reports 7 (1), 8019, 2017 | 33 | 2017 |
| Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson’s disease, causes behavioral alterations but not neurodegeneration in mice N Ageta-Ishihara, H Yamakado, T Morita, S Hattori, K Takao, T Miyakawa, ... Molecular brain 6, 1-14, 2013 | 33 | 2013 |
| Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity MT Uemura, T Asano, R Hikawa, H Yamakado, R Takahashi Neuroscience Research 124, 25-32, 2017 | 29 | 2017 |
| Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract N Uemura, H Yagi, MT Uemura, H Yamakado, R Takahashi Neuroscience letters 716, 134651, 2020 | 28 | 2020 |
| Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases H Kinoshita, H Yamakado, T Kitano, A Kitamura, H Yamashita, ... Journal of neurology 263, 1719-1726, 2016 | 25 | 2016 |
| Perampanel Inhibits α‐Synuclein Transmission in Parkinson's Disease Models J Ueda, N Uemura, M Sawamura, T Taguchi, M Ikuno, S Kaji, Y Taruno, ... Movement Disorders 36 (7), 1554-1564, 2021 | 24 | 2021 |
| Exploring the pathogenetic mechanisms underlying Parkinson's disease in medaka fish H Matsui, N Uemura, H Yamakado, S Takeda, R Takahashi Journal of Parkinson's Disease 4 (2), 301-310, 2014 | 24 | 2014 |
