| Genetic regulation of the RUNX transcription factor family has antitumor effects K Morita, K Suzuki, S Maeda, A Matsuo, Y Mitsuda, C Tokushige, ... The Journal of clinical investigation 127 (7), 2815-2828, 2017 | 119 | 2017 |
| Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts GN Pandian, J Taniguchi, S Junetha, S Sato, L Han, A Saha, ... Scientific reports 4 (1), 3843, 2014 | 71 | 2014 |
| Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity A Saha, GN Pandian, S Sato, J Taniguchi, K Hashiya, T Bando, ... Bioorganic & medicinal chemistry 21 (14), 4201-4209, 2013 | 53 | 2013 |
| Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts GN Pandian, S Sato, C Anandhakumar, J Taniguchi, K Takashima, J Syed, ... ACS chemical biology 9 (12), 2729-2736, 2014 | 50 | 2014 |
| A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into mesoderm J Taniguchi, GN Pandian, T Hidaka, K Hashiya, T Bando, KK Kim, ... Nucleic acids research 45 (16), 9219-9228, 2017 | 49 | 2017 |
| A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell L Han, GN Pandian, S Junetha, S Sato, C Anandhakumar, J Taniguchi, ... Angew. Chem. Int. Ed 52, 13410-13413, 2013 | 44 | 2013 |
| Creation of a synthetic ligand for mitochondrial DNA sequence recognition and promoter-specific transcription suppression T Hidaka, GN Pandian, J Taniguchi, T Nobeyama, K Hashiya, T Bando, ... Journal of the American Chemical Society 139 (25), 8444-8447, 2017 | 41 | 2017 |
| A synthetic DNA‐binding domain guides distinct chromatin‐modifying small molecules to activate an identical gene network L Han, GN Pandian, A Chandran, S Sato, J Taniguchi, G Kashiwazaki, ... Angewandte Chemie 127 (30), 8824-8827, 2015 | 41 | 2015 |
| Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide J Syed, GN Pandian, S Sato, J Taniguchi, A Chandran, K Hashiya, ... Chemistry & biology 21 (10), 1370-1380, 2014 | 40 | 2014 |
| RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells Y Mitsuda, K Morita, G Kashiwazaki, J Taniguchi, T Bando, M Obara, ... Scientific reports 8 (1), 6423, 2018 | 36 | 2018 |
| Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells K Morita, M Noura, C Tokushige, S Maeda, H Kiyose, G Kashiwazaki, ... Scientific reports 7 (1), 16604, 2017 | 36 | 2017 |
| Biomimetic artificial epigenetic code for targeted acetylation of histones J Taniguchi, Y Feng, GN Pandian, F Hashiya, T Hidaka, K Hashiya, ... Journal of the American Chemical Society 140 (23), 7108-7115, 2018 | 31 | 2018 |
| Cellular reprogramming for pancreatic β-cell regeneration: clinical potential of small molecule control GN Pandian, J Taniguchi, H Sugiyama Clinical and Translational Medicine 3, 1-12, 2014 | 27 | 2014 |
| Antiproliferative and apoptotic activities of sequence-specific histone acetyltransferase inhibitors Z Yu, J Taniguchi, Y Wei, GN Pandian, K Hashiya, T Bando, H Sugiyama European Journal of Medicinal Chemistry 138, 320-327, 2017 | 23 | 2017 |
| RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice K Morita, C Tokushige, S Maeda, H Kiyose, M Noura, A Iwai, M Yamada, ... Blood Advances 2 (5), 509-515, 2018 | 21 | 2018 |
| A synthetic transcriptional activator of genes associated with the retina in human dermal fibroblasts J Syed, A Chandran, GN Pandian, J Taniguchi, S Sato, K Hashiya, ... ChemBioChem 16 (10), 1497-1501, 2015 | 21 | 2015 |
| Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions K Morita, S Maeda, K Suzuki, H Kiyose, J Taniguchi, PP Liu, H Sugiyama, ... Blood Advances 1 (18), 1440-1451, 2017 | 20 | 2017 |
| Predictive value of interim FDG-PET/CT findings in patients with diffuse large B-cell lymphoma treated with R-CHOP K Kitajima, M Okada, K Yoshihara, T Tokugawa, A Sawada, S Yoshihara, ... Oncotarget 10 (52), 5403, 2019 | 19 | 2019 |
| A Multi‐target Small Molecule for Targeted Transcriptional Activation of Therapeutically Significant Nervous System Genes Y Wei, GN Pandian, T Zou, J Taniguchi, S Sato, G Kashiwazaki, ... ChemistryOpen 5 (6), 517-521, 2016 | 17 | 2016 |
| A synthetic transcription factor pair mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus Z Yu, M Ai, SK Samanta, F Hashiya, J Taniguchi, S Asamitsu, S Ikeda, ... Chemical communications 56 (15), 2296-2299, 2020 | 16 | 2020 |
