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Huijuan You
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Year
Stability and Kinetics of c-MYC Promoter G-Quadruplexes Studied by Single-Molecule Manipulation
H You, J Wu, F Shao, J Yan
Journal of the American Chemical Society 137 (7), 2424-2427, 2015
962015
Dynamics and stability of polymorphic human telomeric G-quadruplex under tension
H You, X Zeng, Y Xu, CJ Lim, AK Efremov, AT Phan, J Yan
Nucleic acids research 42 (13), 8789-8795, 2014
822014
Folding/unfolding kinetics of G-quadruplexes upstream of the P1 promoter of the human BCL-2 oncogene
Y Cheng, Q Tang, Y Li, Y Zhang, C Zhao, J Yan, H You
Journal of Biological Chemistry 294 (15), 5890-5895, 2019
462019
Structural–elastic determination of the force-dependent transition rate of biomolecules
S Guo, Q Tang, M Yao, H You, S Le, H Chen, J Yan
Chemical science 9 (27), 5871-5882, 2018
452018
The mechanical properties of RNA-DNA hybrid duplex stretched by magnetic tweezers
C Zhang, H Fu, Y Yang, E Zhou, Z Tan, H You, X Zhang
Biophysical journal 116 (2), 196-204, 2019
442019
RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis
H You, S Lattmann, D Rhodes, J Yan
Nucleic acids research 45 (1), 206-214, 2017
442017
Single-molecule imaging and manipulation of biomolecular machines and systems
R Iino, T Iida, A Nakamura, E Saita, H You, Y Sako
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (2), 241-252, 2018
212018
Torque transmission mechanism via DELSEED loop of F1-ATPase
R Watanabe, K Koyasu, H You, M Tanigawara, H Noji
Biophysical journal 108 (5), 1144-1152, 2015
202015
Winding single-molecule double-stranded DNA on a nanometer-sized reel
H You, R Iino, R Watanabe, H Noji
Nucleic acids research 40 (19), e151-e151, 2012
192012
Characterization of G-quadruplexes folding/unfolding dynamics and interactions with proteins from single-molecule force spectroscopy
Y Cheng, Y Zhang, H You
Biomolecules 11 (11), 1579, 2021
172021
Two-state folding energy determination based on transition points in nonequilibrium single-molecule experiments
H You, S Guo, S Le, Q Tang, M Yao, X Zhao, J Yan
The journal of physical chemistry letters 9 (4), 811-816, 2018
132018
High mechanical stability and slow unfolding rates are prevalent in parallel-stranded DNA G-quadruplexes
Y Cheng, Y Zhang, Z Gong, X Zhang, Y Li, X Shi, Y Pei, H You
The Journal of Physical Chemistry Letters 11 (19), 7966-7971, 2020
122020
ZYH005, a novel DNA intercalator, overcomes all-trans retinoic acid resistance in acute promyelocytic leukemia
Q Tong, H You, X Chen, K Wang, W Sun, Y Pei, X Zhao, M Yuan, H Zhu, ...
Nucleic Acids Research 46 (7), 3284-3297, 2018
122018
A universal assay for making DNA, RNA, and RNA–DNA hybrid configurations for single-molecule manipulation in two or three steps without ligation
YJ Yang, L Song, XC Zhao, C Zhang, WQ Wu, HJ You, H Fu, EC Zhou, ...
ACS Synthetic Biology 8 (7), 1663-1672, 2019
112019
Mechanical diversity and folding intermediates of parallel-stranded G-quadruplexes with a bulge
Y Zhang, Y Cheng, J Chen, K Zheng, H You
Nucleic Acids Research 49 (12), 7179-7188, 2021
102021
Detecting the formation kinetics of doxorubicin-DNA interstrand cross-link at the single-molecule level and clinically relevant concentrations of doxorubicin
Y Pei, Y Liu, C Xie, X Zhang, H You
Analytical chemistry 92 (6), 4504-4511, 2020
102020
The holdase function of Escherichia coli Hsp70 (DnaK) chaperone
RS Winardhi, Q Tang, H You, M Sheetz, J Yan
bioRxiv, 305854, 2018
92018
Single-molecule manipulation of G-quadruplexes by magnetic tweezers
H You, S Le, H Chen, L Qin, J Yan
JoVE (Journal of Visualized Experiments), e56328, 2017
82017
Using magnetic tweezers to unravel the mechanism of the G-quadruplex binding and unwinding activities of DHX36 helicase
H You, Y Zhou, J Yan
RNA Remodeling Proteins: Methods and Protocols, 175-191, 2021
52021
Single-molecule mechanical unfolding of AT-rich chromosomal fragile site DNA hairpins: resolving the thermodynamic and kinetic effects of a single GT mismatch
X Li, Y Pei, Y Zhang, Y Liu, W Fu, J Li, H You, J Huang
The Journal of Physical Chemistry B 124 (42), 9365-9370, 2020
52020
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Articles 1–20